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Conserved domains on  [gi|1159611144|gb|AQY77029|]
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POU5F1, partial [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pou super family cl22952
Pou domain - N-terminal to homeobox domain;
138-191 2.25e-29

Pou domain - N-terminal to homeobox domain;


The actual alignment was detected with superfamily member smart00352:

Pssm-ID: 473999  Cd Length: 75  Bit Score: 103.67  E-value: 2.25e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1159611144  138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQ 191
Cdd:smart00352   1 DDDTDPRELEAFAKQFKQRRIKLGFTQADVGLALGALYGPAFSQTTICRFEALQ 54
 
Name Accession Description Interval E-value
POU smart00352
Found in Pit-Oct-Unc transcription factors;
138-191 2.25e-29

Found in Pit-Oct-Unc transcription factors;


Pssm-ID: 197673  Cd Length: 75  Bit Score: 103.67  E-value: 2.25e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1159611144  138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQ 191
Cdd:smart00352   1 DDDTDPRELEAFAKQFKQRRIKLGFTQADVGLALGALYGPAFSQTTICRFEALQ 54
Pou pfam00157
Pou domain - N-terminal to homeobox domain;
143-191 5.44e-28

Pou domain - N-terminal to homeobox domain;


Pssm-ID: 459692  Cd Length: 72  Bit Score: 100.04  E-value: 5.44e-28
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1159611144 143 QKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQ 191
Cdd:pfam00157   3 LEELEEFAKEFKQRRIKLGYTQADVGSALGALYGPVFSQSTICRFEKLD 51
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
147-188 2.37e-03

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 35.21  E-value: 2.37e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1159611144 147 EQFAKLLKQKRITLGYTQADVGLTLGVlfgkvfSQTTICRFE 188
Cdd:COG1476     3 KKLGNRLKELRKERGLTQEELAELLGV------SRQTISAIE 38
 
Name Accession Description Interval E-value
POU smart00352
Found in Pit-Oct-Unc transcription factors;
138-191 2.25e-29

Found in Pit-Oct-Unc transcription factors;


Pssm-ID: 197673  Cd Length: 75  Bit Score: 103.67  E-value: 2.25e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1159611144  138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQ 191
Cdd:smart00352   1 DDDTDPRELEAFAKQFKQRRIKLGFTQADVGLALGALYGPAFSQTTICRFEALQ 54
Pou pfam00157
Pou domain - N-terminal to homeobox domain;
143-191 5.44e-28

Pou domain - N-terminal to homeobox domain;


Pssm-ID: 459692  Cd Length: 72  Bit Score: 100.04  E-value: 5.44e-28
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1159611144 143 QKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQ 191
Cdd:pfam00157   3 LEELEEFAKEFKQRRIKLGYTQADVGSALGALYGPVFSQSTICRFEKLD 51
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
147-188 2.37e-03

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 35.21  E-value: 2.37e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1159611144 147 EQFAKLLKQKRITLGYTQADVGLTLGVlfgkvfSQTTICRFE 188
Cdd:COG1476     3 KKLGNRLKELRKERGLTQEELAELLGV------SRQTISAIE 38
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
144-188 2.55e-03

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 35.36  E-value: 2.55e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1159611144 144 KELEQFAKLLKQKRITLGYTQADVGLTLGVlfgkvfSQTTICRFE 188
Cdd:COG1396     3 TLKKALGERLRELRKARGLTQEELAERLGV------SRSTISRIE 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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