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Conserved domains on  [gi|313104149|sp|Q8N130|]
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RecName: Full=Sodium-dependent phosphate transport protein 2C; Short=Sodium-phosphate transport protein 2C; AltName: Full=Na(+)-dependent phosphate cotransporter 2C; AltName: Full=Sodium/inorganic phosphate cotransporter IIC; AltName: Full=Sodium/phosphate cotransporter 2C; Short=Na(+)/Pi cotransporter 2C; Short=NaPi-2c; AltName: Full=Solute carrier family 34 member 3

Protein Classification

sodium-dependent phosphate transport protein 2( domain architecture ID 11490082)

sodium-dependent phosphate transport protein 2 may be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
 80-563 1.25e-102

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


:

Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 318.34  E-value: 1.25e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149   80 LGSLYFFICSLDVLSSAFQLLGSKVAGDIFKDNVVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPI 159
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  160 IMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLESATALLERLSELALGAASLTPRAQAPDIL 239
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  240 KVLTKPLTHLIVQLDSDMImsSATGNATNSSLIKHWCGTTGqptqensscgafgpcteKNSTAPADRLPCRHLFagtelt 319
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLII--RLIGSLLILPLIDILASTLS-----------------SLPVPESNLPIEAHIF------ 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  320 dLAVGCILLAGSLLVLCGCLVLIVKLLNSVLRGRVAQVVRTVINADFPFPLGWLGGYLAVLAGAGLTFALQSSSVFTAAV 399
Cdd:TIGR01013 216 -VNVGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTFIIQSSSVFTSAL 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  400 VPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADRMLSALQVALIHFFFNLAGILLWYLVPALRLPIPLARHFGV 479
Cdd:TIGR01013 295 TPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCTRKPIAAARGFGD 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  480 VTARYRWVAGVYLLLGFLLLPLAAFGLSLAGGMELAAVGGPLVGLVLLVILVTVLQRRRPAwlPVRLRSWAWLPVWLHSL 559
Cdd:TIGR01013 375 DGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQTWSFLPDWLRSL 452


                  ....
gi 313104149  560 EPWD 563
Cdd:TIGR01013 453 KRLD 456
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
 80-563 1.25e-102

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 318.34  E-value: 1.25e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149   80 LGSLYFFICSLDVLSSAFQLLGSKVAGDIFKDNVVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPI 159
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  160 IMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLESATALLERLSELALGAASLTPRAQAPDIL 239
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  240 KVLTKPLTHLIVQLDSDMImsSATGNATNSSLIKHWCGTTGqptqensscgafgpcteKNSTAPADRLPCRHLFagtelt 319
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLII--RLIGSLLILPLIDILASTLS-----------------SLPVPESNLPIEAHIF------ 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  320 dLAVGCILLAGSLLVLCGCLVLIVKLLNSVLRGRVAQVVRTVINADFPFPLGWLGGYLAVLAGAGLTFALQSSSVFTAAV 399
Cdd:TIGR01013 216 -VNVGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTFIIQSSSVFTSAL 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  400 VPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADRMLSALQVALIHFFFNLAGILLWYLVPALRLPIPLARHFGV 479
Cdd:TIGR01013 295 TPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCTRKPIAAARGFGD 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  480 VTARYRWVAGVYLLLGFLLLPLAAFGLSLAGGMELAAVGGPLVGLVLLVILVTVLQRRRPAwlPVRLRSWAWLPVWLHSL 559
Cdd:TIGR01013 375 DGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQTWSFLPDWLRSL 452


                  ....
gi 313104149  560 EPWD 563
Cdd:TIGR01013 453 KRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
377-464 5.98e-12

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 68.28  E-value: 5.98e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149 377 LAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADrmlsALQVALIHFFFNLA 456
Cdd:COG1283  176 LGVLVGALLTALVQSSSATVGLLLALAAQGLIPLEAALALVLGANIGTTITALLASIGANVA----ARRAALAHLLFNLI 251


                 ....*...
gi 313104149 457 GILLWYLV 464
Cdd:COG1283  252 GVLIFLPL 259
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
 85-176 6.46e-10

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 57.41  E-value: 6.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149   85 FFICSLDVLSSAFQllgsKVAGDIFKD--NVVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPIIMG 162
Cdd:pfam02690   1 LFLFGMKLMSDGLQ----KLAGGRLRRilEKLTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMG 76

                          90
                  ....*....|....
gi 313104149  163 VNVGTSITSTLVSM 176
Cdd:pfam02690  77 ANIGTTVTAQLIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
 376-462 5.88e-04

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 42.20  E-value: 5.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149 376 YLAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADrmlsALQVALIHFFFNL 455
Cdd:NF037997 165 LLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSGKE----AKLTAYAHIWLNV 240


                 ....*..
gi 313104149 456 AGILLWY 462
Cdd:NF037997 241 LGVLLFL 247
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
 97-175 7.74e-04

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 41.82  E-value: 7.74e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 313104149  97 FQLLGSKVAGDIFKdnvVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPIIMGVNVGTSITSTLVS 175
Cdd:NF037997  20 FNLSGHKLKTWLLK---FTDTPLKGFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFIT 95
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
 80-563 1.25e-102

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 318.34  E-value: 1.25e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149   80 LGSLYFFICSLDVLSSAFQLLGSKVAGDIFKDNVVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPI 159
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  160 IMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLESATALLERLSELALGAASLTPRAQAPDIL 239
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  240 KVLTKPLTHLIVQLDSDMImsSATGNATNSSLIKHWCGTTGqptqensscgafgpcteKNSTAPADRLPCRHLFagtelt 319
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLII--RLIGSLLILPLIDILASTLS-----------------SLPVPESNLPIEAHIF------ 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  320 dLAVGCILLAGSLLVLCGCLVLIVKLLNSVLRGRVAQVVRTVINADFPFPLGWLGGYLAVLAGAGLTFALQSSSVFTAAV 399
Cdd:TIGR01013 216 -VNVGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTFIIQSSSVFTSAL 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  400 VPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADRMLSALQVALIHFFFNLAGILLWYLVPALRLPIPLARHFGV 479
Cdd:TIGR01013 295 TPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCTRKPIAAARGFGD 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  480 VTARYRWVAGVYLLLGFLLLPLAAFGLSLAGGMELAAVGGPLVGLVLLVILVTVLQRRRPAwlPVRLRSWAWLPVWLHSL 559
Cdd:TIGR01013 375 DGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQTWSFLPDWLRSL 452


                  ....
gi 313104149  560 EPWD 563
Cdd:TIGR01013 453 KRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
377-464 5.98e-12

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 68.28  E-value: 5.98e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149 377 LAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADrmlsALQVALIHFFFNLA 456
Cdd:COG1283  176 LGVLVGALLTALVQSSSATVGLLLALAAQGLIPLEAALALVLGANIGTTITALLASIGANVA----ARRAALAHLLFNLI 251


                 ....*...
gi 313104149 457 GILLWYLV 464
Cdd:COG1283  252 GVLIFLPL 259
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
 85-176 6.46e-10

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 57.41  E-value: 6.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149   85 FFICSLDVLSSAFQllgsKVAGDIFKD--NVVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPIIMG 162
Cdd:pfam02690   1 LFLFGMKLMSDGLQ----KLAGGRLRRilEKLTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMG 76

                          90
                  ....*....|....
gi 313104149  163 VNVGTSITSTLVSM 176
Cdd:pfam02690  77 ANIGTTVTAQLIAF 90
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
 376-423 5.21e-08

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 52.02  E-value: 5.21e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 313104149  376 YLAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIG 423
Cdd:pfam02690  33 LKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIG 80
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
377-423 4.76e-05

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 46.33  E-value: 4.76e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 313104149 377 LAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIG 423
Cdd:COG1283   49 KGVLAGALVTALLQSSSATTVMVVGFVNAGLMTLAQALGVILGANIG 95
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
 376-462 5.88e-04

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 42.20  E-value: 5.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149 376 YLAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADrmlsALQVALIHFFFNL 455
Cdd:NF037997 165 LLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSGKE----AKLTAYAHIWLNV 240


                 ....*..
gi 313104149 456 AGILLWY 462
Cdd:NF037997 241 LGVLLFL 247
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
 97-175 7.74e-04

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 41.82  E-value: 7.74e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 313104149  97 FQLLGSKVAGDIFKdnvVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPIIMGVNVGTSITSTLVS 175
Cdd:NF037997  20 FNLSGHKLKTWLLK---FTDTPLKGFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFIT 95
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
65-209 8.36e-04

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 42.09  E-value: 8.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  65 RLRRVaGSVLKACGLLgslyFFicSLDVLSSAFQ-LLGSKVAGDIFkdnVVLS-NPVAGLVIGVLVTALVQSSSTSSSIV 142
Cdd:COG1283  129 RLRQI-GRILIGFGLL----FL--GLDLMSEAMEpLRDSPAFRALL---ASLSgNPLLGVLVGALLTALVQSSSATVGLL 198

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 313104149 143 VSMVAAKLLTVRVSVPIIMGVNVGTSITSTLVSMAQSGDRdefQRAfsgSAVHGIFNWLTVLVLLPL 209
Cdd:COG1283  199 LALAAQGLIPLEAALALVLGANIGTTITALLASIGANVAA---RRA---ALAHLLFNLIGVLIFLPL 259
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
 376-460 4.29e-03

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 39.52  E-value: 4.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104149  376 YLAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPAdrmlSALQVALIHFFFNL 455
Cdd:TIGR00704 172 LLAALIGAMFAAIIHSSLAAIGILASFMAAGIIGFPQALCLVIGANIGSCILAMLAASAAGA----AAKQTALAHLLFKL 247


                  ....*
gi 313104149  456 AGILL 460
Cdd:TIGR00704 248 LGSAI 252
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
 377-423 9.48e-03

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 38.36  E-value: 9.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 313104149  377 LAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIG 423
Cdd:TIGR00704  46 KAFCAGIGFTAILQSSNAFMMIVIGFVAADLLAFAPAIPIILGADVG 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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