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Conserved domains on  [gi|733898471|ref|XP_010713297|]
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zinc finger MYM-type protein 3 isoform X2 [Meleagris gallopavo]

Protein Classification

eL24 family ribosomal protein( domain architecture ID 10534359)

eL24 family ribosomal protein such as archaea 50S ribosomal protein L24, and algae 60S ribosomal protein L24

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1131-1299 7.56e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 267.60  E-value: 7.56e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  1131 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTargvTKMVSIRYCAPAKQk 1210
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPR----EKSTYLRYYEPPDQ- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  1211 kgrdGSTGKRKREEEM--PMLEQRENKMNPLRCPVKFYEFYLSKCPESMRNRNDIFYLQPERSCIAESPLWYSVIPMDRS 1288
Cdd:pfam12012   76 ----VETGGRKKRDEGvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 733898471  1289 MLESMLNRILV 1299
Cdd:pfam12012  152 TLESMLTRILL 162
TRASH smart00746
metallochaperone-like domain;
521-560 2.55e-08

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 50.84  E-value: 2.55e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 733898471    521 CDYCGLYIYNKGMPVEYLFhEGQQKRFCNSSCLNSYKKKN 560
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVN-DGKVYYFCSSKCLSKFKKKR 39
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 124-350 9.85e-08

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 56.72  E-value: 9.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  124 AQPSQDGEGGMGDSSAVSKEALVPETQKEGEDAPKTNSGDLK----EDGAAAIPALSDENGPESPPQPAPDSGDLSSAPA 199
Cdd:PHA03307   98 ASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRpvgsPGPPPAASPPAAGASPAAVASDAASSRQAALPLS 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  200 IEETTAQPSSPPVAPPQLSlKQPKKTRLKAPRKSSPVQ-----REGLPGDAEGELRPDSSMAALPSEPAQEKKAEEwNDD 274
Cdd:PHA03307  178 SPEETARAPSSPPAEPPPS-TPPAAASPRPPRRSSPISasassPAPAPGRSAADDAGASSSDSSSSESSGCGWGPE-NEC 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  275 GNNSLRESTGPRAEEAALPAEGlsrKGSVPQTEKEKRSERARRSESAR---------PETVNSAESIPVSDEDSDAMVDD 345
Cdd:PHA03307  256 PLPRPAPITLPTRIWEASGWNG---PSSRPGPASSSSSPRERSPSPSPsspgsgpapSSPRASSSSSSSRESSSSSTSSS 332


                  ....*
gi 733898471  346 PNDED 350
Cdd:PHA03307  333 SESSR 337
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 654-691 2.22e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.44  E-value: 2.22e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   654 GIHLNCHYCHNLFTGKPE--ILDWQDKMYQFCCKDCCEDF 691
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 561-600 1.20e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.20e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   561 TRVYPCMWCKTLCKNFDMLPNVDRSGKMGLFCSICCTTSH 600
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 609-646 3.70e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 39.28  E-value: 3.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   609 GPPRPCSFCRKSLSEPCYYNKTDR--VVYQFCSPSCWTKF 646
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 423-459 4.47e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.89  E-value: 4.47e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 733898471   423 CTFCKKEIWNTRDsvVAQIGSGGSFHEFCTSVCLSLY 459
Cdd:pfam06467    6 CWFCKKLIKNKPT--VIVLQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1131-1299 7.56e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 267.60  E-value: 7.56e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  1131 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTargvTKMVSIRYCAPAKQk 1210
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPR----EKSTYLRYYEPPDQ- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  1211 kgrdGSTGKRKREEEM--PMLEQRENKMNPLRCPVKFYEFYLSKCPESMRNRNDIFYLQPERSCIAESPLWYSVIPMDRS 1288
Cdd:pfam12012   76 ----VETGGRKKRDEGvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 733898471  1289 MLESMLNRILV 1299
Cdd:pfam12012  152 TLESMLTRILL 162
TRASH smart00746
metallochaperone-like domain;
521-560 2.55e-08

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 50.84  E-value: 2.55e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 733898471    521 CDYCGLYIYNKGMPVEYLFhEGQQKRFCNSSCLNSYKKKN 560
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVN-DGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 516-556 3.91e-08

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 50.45  E-value: 3.91e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 733898471   516 LKTNCCDYCGLYIYNKGMpVEYLFHEGQQKRFCNSSCLNSY 556
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPT-VIVLQNDGSVGQFCSQSCLDSY 40
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 124-350 9.85e-08

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 56.72  E-value: 9.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  124 AQPSQDGEGGMGDSSAVSKEALVPETQKEGEDAPKTNSGDLK----EDGAAAIPALSDENGPESPPQPAPDSGDLSSAPA 199
Cdd:PHA03307   98 ASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRpvgsPGPPPAASPPAAGASPAAVASDAASSRQAALPLS 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  200 IEETTAQPSSPPVAPPQLSlKQPKKTRLKAPRKSSPVQ-----REGLPGDAEGELRPDSSMAALPSEPAQEKKAEEwNDD 274
Cdd:PHA03307  178 SPEETARAPSSPPAEPPPS-TPPAAASPRPPRRSSPISasassPAPAPGRSAADDAGASSSDSSSSESSGCGWGPE-NEC 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  275 GNNSLRESTGPRAEEAALPAEGlsrKGSVPQTEKEKRSERARRSESAR---------PETVNSAESIPVSDEDSDAMVDD 345
Cdd:PHA03307  256 PLPRPAPITLPTRIWEASGWNG---PSSRPGPASSSSSPRERSPSPSPsspgsgpapSSPRASSSSSSSRESSSSSTSSS 332


                  ....*
gi 733898471  346 PNDED 350
Cdd:PHA03307  333 SESSR 337
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 654-691 2.22e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.44  E-value: 2.22e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   654 GIHLNCHYCHNLFTGKPE--ILDWQDKMYQFCCKDCCEDF 691
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 561-600 1.20e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.20e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   561 TRVYPCMWCKTLCKNFDMLPNVDRSGKMGLFCSICCTTSH 600
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 2-349 1.75e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 49.24  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471    2 DSSEISGSLDPLSLPDKPLIGDLPADMEFGED-LLGSQTASTQEAAVLRPPDWDQSKQMTADGDLGLQEKGDSLSEQNKS 80
Cdd:COG5271   122 DDADSSGDAQGDPLATDTLGGGDLDLATKDGDeLLPSLADNDEAAADEGDELAADGDDTLAVADAIEATPGGTDAVELTA 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   81 SDLSLDKPGAVLDVLEKPDVLDDLDGTAGSVENKSEDLDELCKAQPSQDGEGGMGDSSAVSKEALVPETQKEGEDAPktN 160
Cdd:COG5271   202 TLGATVTTDPGDSVAADDDLAAEEGASAVVEEEDASEDAVAAADETLLADDDDTESAGATAEVGGTPDTDDEATDDA--D 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  161 SGDLKEDGAAAIPALSDENGPESPPQPAPDSGDLSSAPAIEETTAqpssppVAPPQLSLKQPKKTRLKAPRKSSPVQREG 240
Cdd:COG5271   280 GLEAAEDDALDAELTAAQAADPESDDDADDSTLAALEGAAEDTEI------ATADELAAADDEDDDDSAAEDAAEEAATA 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  241 LPGDAEGELRPDSsmaALPSEPAQEKKAEEWNDDGNNSLRESTGPRAEEAALPAEGLSRKGSVPQTEKEK-RSERARRSE 319
Cdd:COG5271   354 EDSAAEDTQDAED---EAAGEAADESEGADTDAAADEADAAADDSADDEEASADGGTSPTSDTDEEEEEAdEDASAGETE 430

                         330       340       350
                  ....*....|....*....|....*....|
gi 733898471  320 SARPETVNSAESIPvSDEDSDAMVDDPNDE 349
Cdd:COG5271   431 DESTDVTSAEDDIA-TDEEADSLADEEEEA 459
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 609-646 3.70e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 39.28  E-value: 3.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   609 GPPRPCSFCRKSLSEPCYYNKTDR--VVYQFCSPSCWTKF 646
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 423-459 4.47e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.89  E-value: 4.47e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 733898471   423 CTFCKKEIWNTRDsvVAQIGSGGSFHEFCTSVCLSLY 459
Cdd:pfam06467    6 CWFCKKLIKNKPT--VIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
659-695 7.69e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 7.69e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 733898471    659 CHYCHNLF--TGKPEILDWQDKMYQFCCKDCCEDFKRLR 695
Cdd:smart00746    1 CSFCGKDIynPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
SRP-alpha_N pfam04086
Signal recognition particle, alpha subunit, N-terminal; SRP is a complex of six distinct ...
 137-276 1.06e-03

Signal recognition particle, alpha subunit, N-terminal; SRP is a complex of six distinct polypeptides and a 7S RNA that is essential for transferring nascent polypeptide chains that are destined for export from the cell to the translocation apparatus of the endoplasmic reticulum (ER) membrane. SRP binds hydrophobic signal sequences as they emerge from the ribosome, and arrests translation.


Pssm-ID: 461165  Cd Length: 281  Bit Score: 42.40  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   137 SSAVSKEALVPETQKEGEDAPKTNSgDLKEDGAAAIPALSDENGPESPPQPAPDSGDlSSAPAIEETTAQPSSPPVAPPQ 216
Cdd:pfam04086   98 AAAQAKAPKAMKTFEESKKSQKTVK-SMIEDRPPPPPGKKKKGAKKEAPAAGDAGSD-DSTPSATPDTSRPSTPLLTAKG 175

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   217 LSLKQPKKTRLKapRKSspvQREGLPGDAEGELRPDSSMAALPSEPAQEKKAEEWNDDGN 276
Cdd:pfam04086  176 AGPGAGDVSRRN--RKA---LNKKRSGAGASSGDESSKSPKPPKKKKKGKKARVWDADGS 230
TRASH smart00746
metallochaperone-like domain;
614-647 5.35e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 5.35e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 733898471    614 CSFCRKSLSEPCYYNKT--DRVVYQFCSPSCWTKFQ 647
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1131-1299 7.56e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 267.60  E-value: 7.56e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  1131 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTargvTKMVSIRYCAPAKQk 1210
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPR----EKSTYLRYYEPPDQ- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  1211 kgrdGSTGKRKREEEM--PMLEQRENKMNPLRCPVKFYEFYLSKCPESMRNRNDIFYLQPERSCIAESPLWYSVIPMDRS 1288
Cdd:pfam12012   76 ----VETGGRKKRDEGvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 733898471  1289 MLESMLNRILV 1299
Cdd:pfam12012  152 TLESMLTRILL 162
TRASH smart00746
metallochaperone-like domain;
521-560 2.55e-08

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 50.84  E-value: 2.55e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 733898471    521 CDYCGLYIYNKGMPVEYLFhEGQQKRFCNSSCLNSYKKKN 560
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVN-DGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 516-556 3.91e-08

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 50.45  E-value: 3.91e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 733898471   516 LKTNCCDYCGLYIYNKGMpVEYLFHEGQQKRFCNSSCLNSY 556
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPT-VIVLQNDGSVGQFCSQSCLDSY 40
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 124-350 9.85e-08

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 56.72  E-value: 9.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  124 AQPSQDGEGGMGDSSAVSKEALVPETQKEGEDAPKTNSGDLK----EDGAAAIPALSDENGPESPPQPAPDSGDLSSAPA 199
Cdd:PHA03307   98 ASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRpvgsPGPPPAASPPAAGASPAAVASDAASSRQAALPLS 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  200 IEETTAQPSSPPVAPPQLSlKQPKKTRLKAPRKSSPVQ-----REGLPGDAEGELRPDSSMAALPSEPAQEKKAEEwNDD 274
Cdd:PHA03307  178 SPEETARAPSSPPAEPPPS-TPPAAASPRPPRRSSPISasassPAPAPGRSAADDAGASSSDSSSSESSGCGWGPE-NEC 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  275 GNNSLRESTGPRAEEAALPAEGlsrKGSVPQTEKEKRSERARRSESAR---------PETVNSAESIPVSDEDSDAMVDD 345
Cdd:PHA03307  256 PLPRPAPITLPTRIWEASGWNG---PSSRPGPASSSSSPRERSPSPSPsspgsgpapSSPRASSSSSSSRESSSSSTSSS 332


                  ....*
gi 733898471  346 PNDED 350
Cdd:PHA03307  333 SESSR 337
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 654-691 2.22e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.44  E-value: 2.22e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   654 GIHLNCHYCHNLFTGKPE--ILDWQDKMYQFCCKDCCEDF 691
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 127-378 1.13e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 50.07  E-value: 1.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  127 SQDGEGGMGDSSAVSKEALVPETQKEGEDAPKtnSGDLKEDGAAAIPALSDE-------------------------NGP 181
Cdd:PTZ00449  529 GEEGEHEDSKESDEPKEGGKPGETKEGEVGKK--PGPAKEHKPSKIPTLSKKpefpkdpkhpkdpeepkkpkrprsaQRP 606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  182 ESPPQPA-PDSGDLSSAPAIEETTAQPSSPPvaPPQ--LSLKQPKKTrlKAPRKSSPVQREGLPGDA--EGELRPDSSMA 256
Cdd:PTZ00449  607 TRPKSPKlPELLDIPKSPKRPESPKSPKRPP--PPQrpSSPERPEGP--KIIKSPKPPKSPKPPFDPkfKEKFYDDYLDA 682

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  257 ALPSepaQEKKAEEWNDDGNNSLRESTG------------------PRAEEAAL--PAEGLSRKGSVPQTEKEKRSERAR 316
Cdd:PTZ00449  683 AAKS---KETKTTVVLDESFESILKETLpetpgtpfttprplppklPRDEEFPFepIGDPDAEQPDDIEFFTPPEEERTF 759

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  317 ------------------RSESARPETVNSAESIPVSDEDSDAMVDDPNDEDFVPFRTRRSTRMSLRTQVAQRAARSVAK 378
Cdd:PTZ00449  760 fhetpadtplpdilaeefKEEDIHAETGEPDEAMKRPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDLESDAGRIAK 839
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 561-600 1.20e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.20e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   561 TRVYPCMWCKTLCKNFDMLPNVDRSGKMGLFCSICCTTSH 600
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 2-349 1.75e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 49.24  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471    2 DSSEISGSLDPLSLPDKPLIGDLPADMEFGED-LLGSQTASTQEAAVLRPPDWDQSKQMTADGDLGLQEKGDSLSEQNKS 80
Cdd:COG5271   122 DDADSSGDAQGDPLATDTLGGGDLDLATKDGDeLLPSLADNDEAAADEGDELAADGDDTLAVADAIEATPGGTDAVELTA 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   81 SDLSLDKPGAVLDVLEKPDVLDDLDGTAGSVENKSEDLDELCKAQPSQDGEGGMGDSSAVSKEALVPETQKEGEDAPktN 160
Cdd:COG5271   202 TLGATVTTDPGDSVAADDDLAAEEGASAVVEEEDASEDAVAAADETLLADDDDTESAGATAEVGGTPDTDDEATDDA--D 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  161 SGDLKEDGAAAIPALSDENGPESPPQPAPDSGDLSSAPAIEETTAqpssppVAPPQLSLKQPKKTRLKAPRKSSPVQREG 240
Cdd:COG5271   280 GLEAAEDDALDAELTAAQAADPESDDDADDSTLAALEGAAEDTEI------ATADELAAADDEDDDDSAAEDAAEEAATA 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  241 LPGDAEGELRPDSsmaALPSEPAQEKKAEEWNDDGNNSLRESTGPRAEEAALPAEGLSRKGSVPQTEKEK-RSERARRSE 319
Cdd:COG5271   354 EDSAAEDTQDAED---EAAGEAADESEGADTDAAADEADAAADDSADDEEASADGGTSPTSDTDEEEEEAdEDASAGETE 430

                         330       340       350
                  ....*....|....*....|....*....|
gi 733898471  320 SARPETVNSAESIPvSDEDSDAMVDDPNDE 349
Cdd:COG5271   431 DESTDVTSAEDDIA-TDEEADSLADEEEEA 459
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
153-341 3.24e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 48.31  E-value: 3.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  153 GEDAPKTNSGDLKEDGAAAIPALSDENGPESPPQPAPdsgdLSSAPAIEETTAQPSSPPVAPPQLSLKQPKKTRLKAPR- 231
Cdd:PRK07003  369 GGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGA----AGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAAd 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  232 KSSPVQreglpGDAEGELRPDSSMAALPSEPAQ--EKKAEEWNDdgnnslreSTGPRAEEAALPAEGLSRKGSVPQTEKE 309
Cdd:PRK07003  445 GDAPVP-----AKANARASADSRCDERDAQPPAdsGSASAPASD--------APPDAAFEPAPRAAAPSAATPAAVPDAR 511

                         170       180       190
                  ....*....|....*....|....*....|..
gi 733898471  310 KRSERARRSESARPETVNSAESIPVSDEDSDA 341
Cdd:PRK07003  512 APAAASREDAPAAAAPPAPEARPPTPAAAAPA 543
PHA03247 PHA03247
large tegument protein UL36; Provisional
 137-350 4.28e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 4.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  137 SSAVSKEALVPETQKEGEDAPktnSGDLKEDGAAAIPALSdengPESPPQPAPDSgdlSSAPAIEETT---AQPSSPPVA 213
Cdd:PHA03247 2838 APPPPPGPPPPSLPLGGSVAP---GGDVRRRPPSRSPAAK----PAAPARPPVRR---LARPAVSRSTesfALPPDQPER 2907

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  214 PPQLSLKQPKKTRLKAPRKSSPVQREGLPGDAEGELRPDSSMAALPSepAQEKKAEEWNddGNNSLRESTGPRAEeaaLP 293
Cdd:PHA03247 2908 PPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGE--PSGAVPQPWL--GALVPGRVAVPRFR---VP 2980

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 733898471  294 AEGLSRKGSVPQTEKEKRSERARRS---------ESARPETVNSAESIPVSDEDSDAMVDDPNDED 350
Cdd:PHA03247 2981 QPAPSREAPASSTPPLTGHSLSRVSswasslalhEETDPPPVSLKQTLWPPDDTEDSDADSLFDSD 3046
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 145-337 7.34e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 47.54  E-value: 7.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  145 LVPETQKEGEDAPKTNSGDLKEDGAAAIPA--LSDENGPE---SPPQPAPDSGDLSSAPAI--EETTAQPSSPPVAPPQ- 216
Cdd:PHA03309  115 FTPPVPDCGRDVGEEAEGAVAPSWRAPLPApqWRPVHGPSwwlSSSSPSGSSRGSVTSPQYsgEETSDAASGAPTPPPQs 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  217 ----------LSLKQPKKTRLKAP-------RKSSPVQREGLPGDAEGE---LRPDSSMAALPSEPAqekKAEEWNDDGN 276
Cdd:PHA03309  195 sgssyvygqaLADLMAMIQEIPAPprsvpdcRRGEPVSEDGMADRCETDascYTTDEPMEAEPSEPA---GGVSWLGERA 271

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 733898471  277 NSLRESTGPRA-------EEAALPAE--GLSRKGSVPQTEKEKRSERARRSESA-RPETVNSAESIPVSDE 337
Cdd:PHA03309  272 DRMRADQSPRGlgaephvAEAGRPSScvGEERADVVAIAAVEERKEAARRSPDAeRNDDEEEYESLPCAQE 342
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 45-375 8.77e-05

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 46.98  E-value: 8.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   45 AAVLRPPDWDQSKQ----MTADGDLGLQEKGDSLSEQNKSSDLSldKPGAVLDVLEKPDvlddlDGTAGSVENKSEDLDE 120
Cdd:COG5180   159 DPILAKDPDGDSAStlppPAEKLDKVLTEPRDALKDSPEKLDRP--KVEVKDEAQEEPP-----DLTGGADHPRPEAASS 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  121 LCKAQPSqdgeggmgDSSAVSKEALVPETQKEGEDAPKTNSGD--LKEDGAAAIPALSDENGPESPPQPAPDSGDLSSAP 198
Cdd:COG5180   232 PKVDPPS--------TSEARSRPATVDAQPEMRPPADAKERRRaaIGDTPAAEPPGLPVLEAGSEPQSDAPEAETARPID 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  199 AIEETTAQPSSPPVAPPQLSLKQpkktrlKAPRKSSPVQR-EGLPGDAEGELRPDSsmAALPSEPAQEKKAEEWNDDGNN 277
Cdd:COG5180   304 VKGVASAPPATRPVRPPGGARDP------GTPRPGQPTERpAGVPEAASDAGQPPS--AYPPAEEAVPGKPLEQGAPRPG 375

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  278 SLRESTGPRAEEAALPAEGLSRKGSVPQTEKEKRSERARRSESARPETVNSAESIPVSDEDSDAMVDDPNDEDFVPFRTR 357
Cdd:COG5180   376 SSGGDGAPFQPPNGAPQPGLGRRGAPGPPMGAGDLVQAALDGGGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAGLA 455

                         330
                  ....*....|....*...
gi 733898471  358 RSTRMSLRTQVAQRAARS 375
Cdd:COG5180   456 DQAGAAASTAMADFVAPV 473
PHA03169 PHA03169
hypothetical protein; Provisional
 87-333 1.11e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 46.12  E-value: 1.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   87 KPGAVLDVLEKPDVLDDLDGTAGSVENKSEDLDELCKAQPSQDGEGGMGDSSAVSKEAlvpETQKEGEDAPKTNSG-DLK 165
Cdd:PHA03169   45 KPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGS---PTPSPSGSAEELASGlSPE 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  166 EDGAAAIPALSDENGPESPP------QPAPDSGDLSSAPAIEETTAQPS---SPPVAPPQLSLKQPKKTRLKAPRKSSPV 236
Cdd:PHA03169  122 NTSGSSPESPASHSPPPSPPshpgphEPAPPESHNPSPNQQPSSFLQPShedSPEEPEPPTSEPEPDSPGPPQSETPTSS 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  237 QREGLPGDAEGElrpdssmaalPSEPAQEKKAEEWNDDGNNSLRESTGPRAEEAALPAEGL-----------SRKGSVPQ 305
Cdd:PHA03169  202 PPPQSPPDEPGE----------PQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRShsytvvgwkpsTRPGGVPK 271

                         250       260
                  ....*....|....*....|....*...
gi 733898471  306 TEKEKRSERARRSESarPETVNSAESIP 333
Cdd:PHA03169  272 LCLRCTSHPSHRSRL--PEGQQSEDKVP 297
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 124-296 2.50e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.36  E-value: 2.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  124 AQPSQDGEGGMGDSSAVSKEAlVPETQKEGEDAPKTNSGDlkeDGAAAIPALSDENGPESPPQPAPDSGDLSSAPAIEET 203
Cdd:PRK07764  628 APAGAAAAPAEASAAPAPGVA-APEHHPKHVAVPDASDGG---DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAP 703

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  204 TAQPSSPPVAPPQLSLKQPKKTRLKAPRKSSPVQREGLPGDAEGELRPDSSMAALPSEPAQEkKAEEWNDdgnnSLREST 283
Cdd:PRK07764  704 APAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPA-PAAAPAA----APPPSP 778

                         170
                  ....*....|...
gi 733898471  284 GPRAEEAALPAEG 296
Cdd:PRK07764  779 PSEEEEMAEDDAP 791
Arc_trans_TRASH pfam08394
Archaeal TRASH domain; This region is found in the C-terminus of a number of archaeal ...
 659-695 2.68e-04

Archaeal TRASH domain; This region is found in the C-terminus of a number of archaeal transcriptional regulators. It is thought to function as a metal-sensing regulatory module.


Pssm-ID: 285580  Cd Length: 37  Bit Score: 39.38  E-value: 2.68e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 733898471   659 CHYCHNLFTGKPEILDWQDKMYQFCCKDCCEDFKRLR 695
Cdd:pfam08394    1 CDYCGKEIVGEPITYKLKNKVYYFCCPTCLSQLKKKL 37
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 609-646 3.70e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 39.28  E-value: 3.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 733898471   609 GPPRPCSFCRKSLSEPCYYNKTDR--VVYQFCSPSCWTKF 646
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 423-459 4.47e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.89  E-value: 4.47e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 733898471   423 CTFCKKEIWNTRDsvVAQIGSGGSFHEFCTSVCLSLY 459
Cdd:pfam06467    6 CWFCKKLIKNKPT--VIVLQNDGSVGQFCSQSCLDSY 40
PHA03247 PHA03247
large tegument protein UL36; Provisional
 162-294 4.75e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 4.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  162 GDLKEDGAAAIPALSDENGPESPPQPAPDSGDLSSAPAIEETTAQPSSPPV----APPQLSLKQPKKTRLKAPRKSSPVQ 237
Cdd:PHA03247 2602 VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPrddpAPGRVSRPRRARRLGRAAQASSPPQ 2681

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 733898471  238 REGLPGdaegeLRPD-SSMAALPSEPAQEKKAEEWNDDGNNSLRESTGPRAEEAALPA 294
Cdd:PHA03247 2682 RPRRRA-----ARPTvGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPA 2734
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 99-331 5.97e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 5.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   99 DVLDDLDGTAGSVENKSEDLDELCKAQPSQDGEGGMGDSSAVSKEALVPETQKEGED-APKTNSGDLKEDGAAAIPALSD 177
Cdd:PHA03307  174 LPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADdAGASSSDSSSSESSGCGWGPEN 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  178 ENG-PESPPQPAPDSGDLSSAPAIEETTAQPSSP--------PVAPPQLSLKQPKKTRLKAPRKSSPVQREGLPGDAEGE 248
Cdd:PHA03307  254 ECPlPRPAPITLPTRIWEASGWNGPSSRPGPASSsssprersPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSS 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  249 LRPDSSMA---ALPSEPAQEKKAEEWNDDGNNSLRESTGPRAE-EAALPAEGLSRKGSVPQTEKEKRSERARRSESARPE 324
Cdd:PHA03307  334 ESSRGAAVspgPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSsPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPR 413


                  ....*..
gi 733898471  325 TVNSAES 331
Cdd:PHA03307  414 PSPLDAG 420
TRASH smart00746
metallochaperone-like domain;
659-695 7.69e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 7.69e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 733898471    659 CHYCHNLF--TGKPEILDWQDKMYQFCCKDCCEDFKRLR 695
Cdd:smart00746    1 CSFCGKDIynPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 168-300 8.36e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 8.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  168 GAAAIPALSDENGPESPPQPAPDSGdlSSAPAIEETTAQPSSPPVAPPQLSLKQPKKTRLKAPRKSSPVQREGLPGDAEG 247
Cdd:PRK07764  389 GGAGAPAAAAPSAAAAAPAAAPAPA--AAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 733898471  248 ELRPDSSMAALPSEPAQEKKAEEwnddGNNSLRESTGPRAEEAALPAEGLSRK 300
Cdd:PRK07764  467 APAPAAAPEPTAAPAPAPPAAPA----PAAAPAAPAAPAAPAGADDAATLRER 515
SRP-alpha_N pfam04086
Signal recognition particle, alpha subunit, N-terminal; SRP is a complex of six distinct ...
 137-276 1.06e-03

Signal recognition particle, alpha subunit, N-terminal; SRP is a complex of six distinct polypeptides and a 7S RNA that is essential for transferring nascent polypeptide chains that are destined for export from the cell to the translocation apparatus of the endoplasmic reticulum (ER) membrane. SRP binds hydrophobic signal sequences as they emerge from the ribosome, and arrests translation.


Pssm-ID: 461165  Cd Length: 281  Bit Score: 42.40  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   137 SSAVSKEALVPETQKEGEDAPKTNSgDLKEDGAAAIPALSDENGPESPPQPAPDSGDlSSAPAIEETTAQPSSPPVAPPQ 216
Cdd:pfam04086   98 AAAQAKAPKAMKTFEESKKSQKTVK-SMIEDRPPPPPGKKKKGAKKEAPAAGDAGSD-DSTPSATPDTSRPSTPLLTAKG 175

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   217 LSLKQPKKTRLKapRKSspvQREGLPGDAEGELRPDSSMAALPSEPAQEKKAEEWNDDGN 276
Cdd:pfam04086  176 AGPGAGDVSRRN--RKA---LNKKRSGAGASSGDESSKSPKPPKKKKKGKKARVWDADGS 230
PHA03169 PHA03169
hypothetical protein; Provisional
 100-335 1.17e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.04  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  100 VLDDLDGTAGSVENKSEDLDELCKAQPSQDGEGGMGDSSAVSKEAlvpetqKEGEDAPKTNSGDLKEDGAAAIPALSDEN 179
Cdd:PHA03169   61 VAEQGHRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTP------SPSGSAEELASGLSPENTSGSSPESPASH 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  180 GPesPPQPAPDSGDLSSAPaieettaqpssppvappqlslkqpkktrlkaprkssPVQREGLPGDA-EGELRPDSSMAAL 258
Cdd:PHA03169  135 SP--PPSPPSHPGPHEPAP------------------------------------PESHNPSPNQQpSSFLQPSHEDSPE 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 733898471  259 PSEPAQEKKAEEWNDDGNNSLRESTGPRAEEAALPAEGLSrkgsvPQTEKEKRSERARRSESARPETVNSAESIPVS 335
Cdd:PHA03169  177 EPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQS-----PTPQQAPSPNTQQAVEHEDEPTEPEREGPPFP 248
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 92-350 2.17e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.73  E-value: 2.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471   92 LDVLEKpdVLDDLDGTAGSVENKSEDL--DELCKAQPSQDGEGGMGDSSAVSKEALVPETQKEGEDAPKTNSGDLKEDGA 169
Cdd:PTZ00108 1134 LDKFEE--ALEEQEEVEEKEIAKEQRLksKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDD 1211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  170 AaiPALSDENGPESPPQ---PAPDSGDLSSAPAIEETTAQPSSPPVAPPQLSLKQPKKTR--LKAPRKSSPVQRegLPGD 244
Cdd:PTZ00108 1212 K--PDNKKSNSSGSDQEddeEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGkpKNAPKRVSAVQY--SPPP 1287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  245 AEGELRPDSSMAALPSEPAQEKKaeewNDDGNNSLRESTGPRAEEAALpaeglSRKGSVPQTEKEKRSERARRSESARPE 324
Cdd:PTZ00108 1288 PSKRPDGESNGGSKPSSPTKKKV----KKRLEGSLAALKKKKKSEKKT-----ARKKKSKTRVKQASASQSSRLLRRPRK 1358

                         250       260
                  ....*....|....*....|....*.
gi 733898471  325 TvnSAESIPVSDEDSDAMVDDPNDED 350
Cdd:PTZ00108 1359 K--KSDSSSEDDDDSEVDDSEDEDDE 1382
PRK12495 PRK12495
hypothetical protein; Provisional
 147-257 2.69e-03

hypothetical protein; Provisional


Pssm-ID: 183558 [Multi-domain]  Cd Length: 226  Bit Score: 41.01  E-value: 2.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  147 PETQKEG--EDAPKTNSGDLKEDGAAAIPALS----DENGPESPPQPAPDSgDLSSAPAIEETTAQPSSPPVAPPQLSLK 220
Cdd:PRK12495   62 PTCQQPVteDGAAGDDAGDGAEATAPSDAGSQaspdDDAQPAAEAEAADQS-APPEASSTSATDEAATDPPATAAARDGP 140

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 733898471  221 QPKKTRLKA--PRKSSPVQREGLPGDAEGELRPDSSMAA 257
Cdd:PRK12495  141 TPDPTAQPAtpDERRSPRQRPPVSGEPPTPSTPDAHVAG 179
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 130-347 3.79e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.70  E-value: 3.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  130 GEGGM-GDSSA-----VSKEALVPETQKEGEDAPKTNSGDLKEDGAAAIPALSDENG--PESPPQPAPDSGDLSSAPAIE 201
Cdd:PHA03307   38 GSQGQlVSDSAelaavTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTlaPASPAREGSPTPPGPSSPDPP 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733898471  202 ETTAQPSSPPVAPPqlslkqpkktrlkaPRKSSPVQREGLPGDaegelRPDSSMAALPSEPAQEkkaeewnddgnnslrE 281
Cdd:PHA03307  118 PPTPPPASPPPSPA--------------PDLSEMLRPVGSPGP-----PPAASPPAAGASPAAV---------------A 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 733898471  282 STGPRAEEAALPA---EGLSRKGSVPQTEKEKRSERARRSESARPETVNSAESIPVSDEDSDAMVDDPN 347
Cdd:PHA03307  164 SDAASSRQAALPLsspEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDA 232
TRASH smart00746
metallochaperone-like domain;
614-647 5.35e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 5.35e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 733898471    614 CSFCRKSLSEPCYYNKT--DRVVYQFCSPSCWTKFQ 647
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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