|
Name |
Accession |
Description |
Interval |
E-value |
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
405-792 |
3.44e-35 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 145.96 E-value: 3.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 405 NRPPIAIVSPQFQEisLPTTSTVIDGSQSTD-DDKIVQYHWEELKGP---LreekISEDTAilKLSKLVP-----GNYTF 475
Cdd:NF038112 1185 NRRPVANAGPDQTV--LERTTVTLNGSGSFDpDGDPLTYAWTQVSGPavtL----TGADTA--TPSFTAPevtadTVLTF 1256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 476 SLTVvdSDGATNSTTANLTVNKA-VDYPPVANAGPNQVITlPQNSITLFGNQSTDDHGITSYEWSlspSSKGKVVEMQGV 554
Cdd:NF038112 1257 QLVV--SDGTKTSAPDTVTVLVRnVNRAPVAVAGAPATVD-ERSTVTLDGSGTDADGDALTYAWT---QTSGPAVTLTGA 1330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 555 RTPTLQLSAMQ---EGDYTYQLTVTDTIgQQATAQVTVIVQPENnKPPQADAGPDKElTLPVDSTTLDGSKSSDDQKIIS 631
Cdd:NF038112 1331 TTATATFTAPEvtaDTQLTFTLTVSDGT-ASATDTVTVTVRNVN-RAPVANAGADQT-VDERSTVTLSGSATDPDGDALT 1407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 632 YLWEKThfffcRGPDgVQLENANSSVATVTGLQVG---TYVFTLTVKDERNLQSQSSVNVIVKEeINKPPIAKiTGNVVI 708
Cdd:NF038112 1408 YAWTQT-----AGPT-VTLTGADTATASFTAPEVAadtELTFQLTVSADGQASADVTVTVTVRN-VNRAPVAH-AGESIT 1479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 709 TLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAgevLNHSDHHPILFLSNLVEG--TYTFHLKVTDAKGESDTDRTTVE 786
Cdd:NF038112 1480 VDEGSTVTLDASATDPDGDTLTYAWTQVAGPSVT---LTGADSAKLTFTAPEVSAdtTLTFSLTVTDGSGSSGPVVVTVT 1556
|
....*.
gi 2217270982 787 VKPDPR 792
Cdd:NF038112 1557 VKNVNR 1562
|
|
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
283-698 |
8.08e-27 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 118.99 E-value: 8.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 283 PSYSYATPTP---QASFQSTSAPYPVIkelvvSAGESVQItLPKNEVQLN--AYVlqePPKGETYTYDW-QLITHPRDYS 356
Cdd:NF038112 1164 LKFTGITNTPftsLVAEPGVCNRRPVA-----NAGPDQTV-LERTTVTLNgsGSF---DPDGDPLTYAWtQVSGPAVTLT 1234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 357 GEMEGKHS----QILKLSKLTpglyeFKVIV-EGQNAHGEGYVNVTVKpepRKNRPPIAivspqfqEISLPTT----STV 427
Cdd:NF038112 1235 GADTATPSftapEVTADTVLT-----FQLVVsDGTKTSAPDTVTVLVR---NVNRAPVA-------VAGAPATvderSTV 1299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 428 -IDGSQSTDDDKIVQYHWEELKGPLREEKiseDTAILKLSKLVP---GNYTFSLTVVDSDG-ATNSTTANLTVnKAVDYP 502
Cdd:NF038112 1300 tLDGSGTDADGDALTYAWTQTSGPAVTLT---GATTATATFTAPevtADTQLTFTLTVSDGtASATDTVTVTV-RNVNRA 1375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 503 PVANAGPNQVITlPQNSITLFGNQSTDDHGITSYEWSlspSSKGKVVEMQGVRTPTLQLSA---MQEGDYTYQLTVTDti 579
Cdd:NF038112 1376 PVANAGADQTVD-ERSTVTLSGSATDPDGDALTYAWT---QTAGPTVTLTGADTATASFTApevAADTELTFQLTVSA-- 1449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 580 GQQATAQVTVIVQPEN-NKPPQADAGPDKELTlPVDSTTLDGSKSSDDQKIISYLWEKThfffcRGPdGVQLENANSSVA 658
Cdd:NF038112 1450 DGQASADVTVTVTVRNvNRAPVAHAGESITVD-EGSTVTLDASATDPDGDTLTYAWTQV-----AGP-SVTLTGADSAKL 1522
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 2217270982 659 TVTGLQVG---TYVFTLTVKDERNLQSQSSVNVIVKEEINKPP 698
Cdd:NF038112 1523 TFTAPEVSadtTLTFSLTVTDGSGSSGPVVVTVTVKNVNRAPD 1565
|
|
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
273-600 |
2.57e-17 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 87.79 E-value: 2.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 273 TQIAVPqPVAPSySYATPTPqaSFQSTSAPYPVIK--ELVVSAGesVQITLPKN-EVQLN-------------------- 329
Cdd:NF038112 1224 TQVSGP-AVTLT-GADTATP--SFTAPEVTADTVLtfQLVVSDG--TKTSAPDTvTVLVRnvnrapvavagapatvders 1297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 330 AYVLQ---EPPKGETYTYDW-QLITHPRDYSGEMEGKHS----QILKLSKLTpglyeFKVIVEGQNAHGEGYVNVTVKPe 401
Cdd:NF038112 1298 TVTLDgsgTDADGDALTYAWtQTSGPAVTLTGATTATATftapEVTADTQLT-----FTLTVSDGTASATDTVTVTVRN- 1371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 402 prKNRPPIAIVSPQfQEISLPTTSTvIDGSQSTDDDKIVQYHWEELKGPlREEKISEDTAILKL---SKLVPGNYTFSLT 478
Cdd:NF038112 1372 --VNRAPVANAGAD-QTVDERSTVT-LSGSATDPDGDALTYAWTQTAGP-TVTLTGADTATASFtapEVAADTELTFQLT 1446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 479 VVDSDGATNSTTANLTVNKaVDYPPVANAGPNQVITlPQNSITLFGNQSTDDHGITSYEWSlspSSKGKVVEMQGVRTPT 558
Cdd:NF038112 1447 VSADGQASADVTVTVTVRN-VNRAPVAHAGESITVD-EGSTVTLDASATDPDGDTLTYAWT---QVAGPSVTLTGADSAK 1521
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2217270982 559 LQLSAMQEG---DYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQ 600
Cdd:NF038112 1522 LTFTAPEVSadtTLTFSLTVTDGSGSSGPVVVTVTVKNVNRAPDG 1566
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
695-785 |
1.15e-11 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 61.52 E-value: 1.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 695 NKPPIAKITGNVVITlPTSTAELDGSKSSD-DKGIVSYLWTRDEGSPAAGEVLNHSDHHPilflsnlveGTYTFHLKVTD 773
Cdd:pfam18911 1 NAAPVADAGGDRIVA-EGETVTFDASASDDpDGDILSYRWDFGDGTTATGANVSHTYAAP---------GTYTVTLTVTD 70
|
90
....*....|....*
gi 2217270982 774 AKG---ESDTDRTTV 785
Cdd:pfam18911 71 DSGasnSTATDTVTV 85
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
700-788 |
4.96e-07 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 48.22 E-value: 4.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 700 AKITGNVVITLPTSTAELDGSkSSDDKGIVSYLWTRDEGSPAAGEVLNHSdhhpilFLSnlvEGTYTFHLKVTDAKGeSD 779
Cdd:smart00089 2 ADVSASPTVGVAGESVTFTAT-SSDDGSIVSYTWDFGDGTSSTGPTVTHT------YTK---PGTYTVTLTVTNAVG-SA 70
|
....*....
gi 2217270982 780 TDRTTVEVK 788
Cdd:smart00089 71 SATVTVVVQ 79
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
698-787 |
1.11e-05 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 44.41 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 698 PIAKITGNVVITLPTStAELDGSKSSDDKgIVSYLWTRDEGSPAAGEvlnhsdhHPILFLSNLVEGTYTFHLKVTDAKGE 777
Cdd:cd00146 1 PTASVSAPPVAELGAS-VTFSASDSSGGS-IVSYKWDFGDGEVSSSG-------EPTVTHTYTKPGTYTVTLTVTNAVGS 71
|
90
....*....|
gi 2217270982 778 SDTDRTTVEV 787
Cdd:cd00146 72 SSTKTTTVVV 81
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
470-740 |
2.07e-04 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 44.66 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 470 PGNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANagPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVV 549
Cdd:COG3291 49 PGTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVT--TSTTVTTLANTANGGATTVVAGSTVGTGVATSTTTAAAPGG 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 550 EMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKI 629
Cdd:COG3291 127 GGGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSG 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 630 ISYLWEKTHFFFcrGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVIT 709
Cdd:COG3291 207 TAGVTTGATSGT--SGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNG 284
|
250 260 270
....*....|....*....|....*....|.
gi 2217270982 710 LPTSTAELDGSKSSDDKGIVSYLWTRDEGSP 740
Cdd:COG3291 285 TGGLGTTTAITPGNVSTTADVTGGTATLAVS 315
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
405-792 |
3.44e-35 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 145.96 E-value: 3.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 405 NRPPIAIVSPQFQEisLPTTSTVIDGSQSTD-DDKIVQYHWEELKGP---LreekISEDTAilKLSKLVP-----GNYTF 475
Cdd:NF038112 1185 NRRPVANAGPDQTV--LERTTVTLNGSGSFDpDGDPLTYAWTQVSGPavtL----TGADTA--TPSFTAPevtadTVLTF 1256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 476 SLTVvdSDGATNSTTANLTVNKA-VDYPPVANAGPNQVITlPQNSITLFGNQSTDDHGITSYEWSlspSSKGKVVEMQGV 554
Cdd:NF038112 1257 QLVV--SDGTKTSAPDTVTVLVRnVNRAPVAVAGAPATVD-ERSTVTLDGSGTDADGDALTYAWT---QTSGPAVTLTGA 1330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 555 RTPTLQLSAMQ---EGDYTYQLTVTDTIgQQATAQVTVIVQPENnKPPQADAGPDKElTLPVDSTTLDGSKSSDDQKIIS 631
Cdd:NF038112 1331 TTATATFTAPEvtaDTQLTFTLTVSDGT-ASATDTVTVTVRNVN-RAPVANAGADQT-VDERSTVTLSGSATDPDGDALT 1407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 632 YLWEKThfffcRGPDgVQLENANSSVATVTGLQVG---TYVFTLTVKDERNLQSQSSVNVIVKEeINKPPIAKiTGNVVI 708
Cdd:NF038112 1408 YAWTQT-----AGPT-VTLTGADTATASFTAPEVAadtELTFQLTVSADGQASADVTVTVTVRN-VNRAPVAH-AGESIT 1479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 709 TLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAgevLNHSDHHPILFLSNLVEG--TYTFHLKVTDAKGESDTDRTTVE 786
Cdd:NF038112 1480 VDEGSTVTLDASATDPDGDTLTYAWTQVAGPSVT---LTGADSAKLTFTAPEVSAdtTLTFSLTVTDGSGSSGPVVVTVT 1556
|
....*.
gi 2217270982 787 VKPDPR 792
Cdd:NF038112 1557 VKNVNR 1562
|
|
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
283-698 |
8.08e-27 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 118.99 E-value: 8.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 283 PSYSYATPTP---QASFQSTSAPYPVIkelvvSAGESVQItLPKNEVQLN--AYVlqePPKGETYTYDW-QLITHPRDYS 356
Cdd:NF038112 1164 LKFTGITNTPftsLVAEPGVCNRRPVA-----NAGPDQTV-LERTTVTLNgsGSF---DPDGDPLTYAWtQVSGPAVTLT 1234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 357 GEMEGKHS----QILKLSKLTpglyeFKVIV-EGQNAHGEGYVNVTVKpepRKNRPPIAivspqfqEISLPTT----STV 427
Cdd:NF038112 1235 GADTATPSftapEVTADTVLT-----FQLVVsDGTKTSAPDTVTVLVR---NVNRAPVA-------VAGAPATvderSTV 1299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 428 -IDGSQSTDDDKIVQYHWEELKGPLREEKiseDTAILKLSKLVP---GNYTFSLTVVDSDG-ATNSTTANLTVnKAVDYP 502
Cdd:NF038112 1300 tLDGSGTDADGDALTYAWTQTSGPAVTLT---GATTATATFTAPevtADTQLTFTLTVSDGtASATDTVTVTV-RNVNRA 1375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 503 PVANAGPNQVITlPQNSITLFGNQSTDDHGITSYEWSlspSSKGKVVEMQGVRTPTLQLSA---MQEGDYTYQLTVTDti 579
Cdd:NF038112 1376 PVANAGADQTVD-ERSTVTLSGSATDPDGDALTYAWT---QTAGPTVTLTGADTATASFTApevAADTELTFQLTVSA-- 1449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 580 GQQATAQVTVIVQPEN-NKPPQADAGPDKELTlPVDSTTLDGSKSSDDQKIISYLWEKThfffcRGPdGVQLENANSSVA 658
Cdd:NF038112 1450 DGQASADVTVTVTVRNvNRAPVAHAGESITVD-EGSTVTLDASATDPDGDTLTYAWTQV-----AGP-SVTLTGADSAKL 1522
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 2217270982 659 TVTGLQVG---TYVFTLTVKDERNLQSQSSVNVIVKEEINKPP 698
Cdd:NF038112 1523 TFTAPEVSadtTLTFSLTVTDGSGSSGPVVVTVTVKNVNRAPD 1565
|
|
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
273-600 |
2.57e-17 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 87.79 E-value: 2.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 273 TQIAVPqPVAPSySYATPTPqaSFQSTSAPYPVIK--ELVVSAGesVQITLPKN-EVQLN-------------------- 329
Cdd:NF038112 1224 TQVSGP-AVTLT-GADTATP--SFTAPEVTADTVLtfQLVVSDG--TKTSAPDTvTVLVRnvnrapvavagapatvders 1297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 330 AYVLQ---EPPKGETYTYDW-QLITHPRDYSGEMEGKHS----QILKLSKLTpglyeFKVIVEGQNAHGEGYVNVTVKPe 401
Cdd:NF038112 1298 TVTLDgsgTDADGDALTYAWtQTSGPAVTLTGATTATATftapEVTADTQLT-----FTLTVSDGTASATDTVTVTVRN- 1371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 402 prKNRPPIAIVSPQfQEISLPTTSTvIDGSQSTDDDKIVQYHWEELKGPlREEKISEDTAILKL---SKLVPGNYTFSLT 478
Cdd:NF038112 1372 --VNRAPVANAGAD-QTVDERSTVT-LSGSATDPDGDALTYAWTQTAGP-TVTLTGADTATASFtapEVAADTELTFQLT 1446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 479 VVDSDGATNSTTANLTVNKaVDYPPVANAGPNQVITlPQNSITLFGNQSTDDHGITSYEWSlspSSKGKVVEMQGVRTPT 558
Cdd:NF038112 1447 VSADGQASADVTVTVTVRN-VNRAPVAHAGESITVD-EGSTVTLDASATDPDGDTLTYAWT---QVAGPSVTLTGADSAK 1521
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2217270982 559 LQLSAMQEG---DYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQ 600
Cdd:NF038112 1522 LTFTAPEVSadtTLTFSLTVTDGSGSSGPVVVTVTVKNVNRAPDG 1566
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
695-785 |
1.15e-11 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 61.52 E-value: 1.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 695 NKPPIAKITGNVVITlPTSTAELDGSKSSD-DKGIVSYLWTRDEGSPAAGEVLNHSDHHPilflsnlveGTYTFHLKVTD 773
Cdd:pfam18911 1 NAAPVADAGGDRIVA-EGETVTFDASASDDpDGDILSYRWDFGDGTTATGANVSHTYAAP---------GTYTVTLTVTD 70
|
90
....*....|....*
gi 2217270982 774 AKG---ESDTDRTTV 785
Cdd:pfam18911 71 DSGasnSTATDTVTV 85
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
700-788 |
4.96e-07 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 48.22 E-value: 4.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 700 AKITGNVVITLPTSTAELDGSkSSDDKGIVSYLWTRDEGSPAAGEVLNHSdhhpilFLSnlvEGTYTFHLKVTDAKGeSD 779
Cdd:smart00089 2 ADVSASPTVGVAGESVTFTAT-SSDDGSIVSYTWDFGDGTSSTGPTVTHT------YTK---PGTYTVTLTVTNAVG-SA 70
|
....*....
gi 2217270982 780 TDRTTVEVK 788
Cdd:smart00089 71 SATVTVVVQ 79
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
502-589 |
1.39e-06 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 47.27 E-value: 1.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 502 PPVANAGPNQVITLPQnSITLFGNQSTD-DHGITSYEWSLS--PSSKGKVVemqgVRTptlqlsAMQEGDYTYQLTVTDT 578
Cdd:pfam18911 3 APVADAGGDRIVAEGE-TVTFDASASDDpDGDILSYRWDFGdgTTATGANV----SHT------YAAPGTYTVTLTVTDD 71
|
90
....*....|....
gi 2217270982 579 IGQQ---ATAQVTV 589
Cdd:pfam18911 72 SGASnstATDTVTV 85
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
596-690 |
1.80e-06 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 46.88 E-value: 1.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 596 NKPPQADAGPDKELTlPVDSTTLDGSKSSD-DQKIISYLWEkthFffcrgPDGvqlenanssvATVTGLQV-------GT 667
Cdd:pfam18911 1 NAAPVADAGGDRIVA-EGETVTFDASASDDpDGDILSYRWD---F-----GDG----------TTATGANVshtyaapGT 61
|
90 100
....*....|....*....|...
gi 2217270982 668 YVFTLTVKDERNLQSQSSVNVIV 690
Cdd:pfam18911 62 YTVTLTVTDDSGASNSTATDTVT 84
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
504-592 |
6.38e-06 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 45.13 E-value: 6.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 504 VANAGPNQVITLPQNSITlFGNQSTDDHGITSYEWSLS--PSSKGKVVEMQGVRtptlqlsamqEGDYTYQLTVTDTIGq 581
Cdd:smart00089 1 VADVSASPTVGVAGESVT-FTATSSDDGSIVSYTWDFGdgTSSTGPTVTHTYTK----------PGTYTVTLTVTNAVG- 68
|
90
....*....|.
gi 2217270982 582 QATAQVTVIVQ 592
Cdd:smart00089 69 SASATVTVVVQ 79
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
698-787 |
1.11e-05 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 44.41 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 698 PIAKITGNVVITLPTStAELDGSKSSDDKgIVSYLWTRDEGSPAAGEvlnhsdhHPILFLSNLVEGTYTFHLKVTDAKGE 777
Cdd:cd00146 1 PTASVSAPPVAELGAS-VTFSASDSSGGS-IVSYKWDFGDGEVSSSG-------EPTVTHTYTKPGTYTVTLTVTNAVGS 71
|
90
....*....|
gi 2217270982 778 SDTDRTTVEV 787
Cdd:cd00146 72 SSTKTTTVVV 81
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
503-591 |
4.35e-05 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 42.87 E-value: 4.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 503 PVANAGPNQVITLPQnSITLFGNqSTDDHGITSYEWSLSpsskGKVVEMQGVRTPTLqlSAMQEGDYTYQLTVTDTIGQQ 582
Cdd:cd00146 1 PTASVSAPPVAELGA-SVTFSAS-DSSGGSIVSYKWDFG----DGEVSSSGEPTVTH--TYTKPGTYTVTLTVTNAVGSS 72
|
....*....
gi 2217270982 583 ATAQVTVIV 591
Cdd:cd00146 73 STKTTTVVV 81
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
410-495 |
2.06e-04 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 40.90 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 410 AIVSPQFQEISLPTTSTVIDgsQSTDDDKIVQYHWEELKGPLREEKisedTAILKLSKlvPGNYTFSLTVVDSDGaTNST 489
Cdd:smart00089 2 ADVSASPTVGVAGESVTFTA--TSSDDGSIVSYTWDFGDGTSSTGP----TVTHTYTK--PGTYTVTLTVTNAVG-SASA 72
|
....*.
gi 2217270982 490 TANLTV 495
Cdd:smart00089 73 TVTVVV 78
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
470-740 |
2.07e-04 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 44.66 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 470 PGNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANagPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVV 549
Cdd:COG3291 49 PGTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVT--TSTTVTTLANTANGGATTVVAGSTVGTGVATSTTTAAAPGG 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 550 EMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKI 629
Cdd:COG3291 127 GGGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSG 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 630 ISYLWEKTHFFFcrGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVIT 709
Cdd:COG3291 207 TAGVTTGATSGT--SGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNG 284
|
250 260 270
....*....|....*....|....*....|.
gi 2217270982 710 LPTSTAELDGSKSSDDKGIVSYLWTRDEGSP 740
Cdd:COG3291 285 TGGLGTTTAITPGNVSTTADVTGGTATLAVS 315
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
601-691 |
2.64e-04 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 40.51 E-value: 2.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 601 ADAGPDKELTLPVDSTTLDGSkSSDDQKIISYLWEkthffFCrgpDGVQLENANssvATVTGLQVGTYVFTLTVKDErNL 680
Cdd:smart00089 2 ADVSASPTVGVAGESVTFTAT-SSDDGSIVSYTWD-----FG---DGTSSTGPT---VTHTYTKPGTYTVTLTVTNA-VG 68
|
90
....*....|.
gi 2217270982 681 QSQSSVNVIVK 691
Cdd:smart00089 69 SASATVTVVVQ 79
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
623-690 |
3.90e-04 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 40.17 E-value: 3.90e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217270982 623 SSDDQKIISYLWekthfffCRGPDGVQLENAnsSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIV 690
Cdd:cd00146 23 DSSGGSIVSYKW-------DFGDGEVSSSGE--PTVTHTYTKPGTYTVTLTVTNAVGSSSTKTTTVVV 81
|
|
| REJ |
pfam02010 |
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor ... |
460-698 |
4.42e-04 |
|
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly Swiss:Q26627. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains.
Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 44.03 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 460 TAILKLSKLVPGNYTFSLTVVDSDGATNSTTANLTVN-KAVDYPPVANAGPNQVITLpQNSITLFGNQSTD------DHG 532
Cdd:pfam02010 42 QLTIPSGTLPYGTYVFTLTVSLSSTPSLAGTDIITVTvQPSPLVAVIDGGSSRVVGY-NQDLTLDGSESYDpdvdpgSSS 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 533 ITSYEWS---------LSPSSKGKVVE------MQGVRTPTLQLSA-MQEGDYTYQ--LTVTDTIGQQATAQVTVIVQPE 594
Cdd:pfam02010 121 GLTYLWScrrsssgdnPLLNNDPVCFSdqnegtLLQSTSSSLTIPAsTLQANVTYTfkLTVSKGSRNSASTTQTILVVDG 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 595 NnkPPQAD---AGPDKELTLPVDSTTLDGSKSSDDQKIIS---YLWEKTHFFFcrgpDGVQLENANSSVATVTG------ 662
Cdd:pfam02010 201 N--PPIIIlscISNCNRKNNPVDRLVLLASTCLNCSSDLSdvtYRWLSLGSEN----TSLVLDQLNSQTSTGRSgpylvi 274
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2217270982 663 ----LQVGT-YVFTLTVKDeRNLQSQSSVNVIVKeeINKPP 698
Cdd:pfam02010 275 kagvLQSGVsYRFTLIVTV-YPGLVSGLASISFI--TNAPP 312
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
405-495 |
2.93e-03 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 37.64 E-value: 2.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 405 NRPPIAIVSPQfqEISLPTTSTVIDGSQSTDDD-KIVQYHWEelkgplreekiSEDTAILKLSKLV-----PGNYTFSLT 478
Cdd:pfam18911 1 NAAPVADAGGD--RIVAEGETVTFDASASDDPDgDILSYRWD-----------FGDGTTATGANVShtyaaPGTYTVTLT 67
|
90
....*....|....*...
gi 2217270982 479 VVDSDGATNST-TANLTV 495
Cdd:pfam18911 68 VTDDSGASNSTaTDTVTV 85
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
473-785 |
4.74e-03 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 40.76 E-value: 4.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 473 YTFSLTVVDSDGatNSTTANLTVNKAVDYPPVANAGPNQVITLPqNSITLfgN-QSTDDHGITSYEWSLSPSSKGKVVEM 551
Cdd:COG3401 205 YYYRVAATDTGG--ESAPSNEVSVTTPTTPPSAPTGLTATADTP-GSVTL--SwDPVTESDATGYRVYRSNSGDGPFTKV 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 552 QGVRTPTLQLSAMQEG-DYTYQLTVTDTIGQQATAQVTVIVQPENNkPPQADAGPDKELTLPvDSTTLDGSKSSDDqKII 630
Cdd:COG3401 280 ATVTTTSYTDTGLTNGtTYYYRVTAVDAAGNESAPSNVVSVTTDLT-PPAAPSGLTATAVGS-SSITLSWTASSDA-DVT 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217270982 631 SY-LWEKTHFFfcrGPDGVQLENANSSVATVTGLQVG-TYVFTLTVKDERNLQSQSSvNVIVKEEINKPPIAKITGNVVI 708
Cdd:COG3401 357 GYnVYRSTSGG---GTYTKIAETVTTTSYTDTGLTPGtTYYYKVTAVDAAGNESAPS-EEVSATTASAASGESLTASVDA 432
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217270982 709 TLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTV 785
Cdd:COG3401 433 VPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSV 509
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
431-495 |
5.34e-03 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 37.09 E-value: 5.34e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217270982 431 SQSTDDDKIVQYHWEELKGPLreekISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTANLTV 495
Cdd:cd00146 21 ASDSSGGSIVSYKWDFGDGEV----SSSGEPTVTHTYTKPGTYTVTLTVTNAVGSSSTKTTTVVV 81
|
|
| |
