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Conserved domains on  [gi|263190680|ref|NP_001161081|]
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zinc finger protein GLI1 isoform 3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 521-1040 4.03e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  521 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 597
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  598 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 677
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  678 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 756
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  757 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 836
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  837 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 916
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  917 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 996
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 263190680  997 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1040
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC super family cl24666
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 196-224 2.49e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


The actual alignment was detected with superfamily member pfam16159:

Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.49e-06
                           10        20
                   ....*....|....*....|....*....
gi 263190680   196 CRWDGCSQEFDSQEQLVHHINSEHIHGER 224
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 256-346 4.39e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.49  E-value: 4.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  256 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 335
Cdd:COG5189   346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                          90
                  ....*....|.
gi 263190680  336 SSLRKHVKTVH 346
Cdd:COG5189   412 NGLKYHRKHSH 422
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 521-1040 4.03e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  521 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 597
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  598 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 677
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  678 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 756
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  757 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 836
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  837 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 916
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  917 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 996
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 263190680  997 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1040
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 196-224 2.49e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.49e-06
                           10        20
                   ....*....|....*....|....*....
gi 263190680   196 CRWDGCSQEFDSQEQLVHHINSEHIHGER 224
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 256-346 4.39e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.49  E-value: 4.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  256 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 335
Cdd:COG5189   346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                          90
                  ....*....|.
gi 263190680  336 SSLRKHVKTVH 346
Cdd:COG5189   412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
276-303 2.30e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.30e-05
                           10        20
                   ....*....|....*....|....*...
gi 263190680   276 NLKTHLRSHTGEKPYMCEHegCSKAFSN 303
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
155-392 1.96e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  155 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 227
Cdd:COG5236   117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  228 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 298
Cdd:COG5236   193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  299 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 357
Cdd:COG5236   258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 263190680  358 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 392
Cdd:COG5236   333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 521-1040 4.03e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  521 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 597
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  598 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 677
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  678 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 756
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  757 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 836
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  837 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 916
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  917 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 996
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 263190680  997 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1040
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 196-224 2.49e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.49e-06
                           10        20
                   ....*....|....*....|....*....
gi 263190680   196 CRWDGCSQEFDSQEQLVHHINSEHIHGER 224
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 256-346 4.39e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.49  E-value: 4.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  256 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 335
Cdd:COG5189   346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                          90
                  ....*....|.
gi 263190680  336 SSLRKHVKTVH 346
Cdd:COG5189   412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
276-303 2.30e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.30e-05
                           10        20
                   ....*....|....*....|....*...
gi 263190680   276 NLKTHLRSHTGEKPYMCEHegCSKAFSN 303
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
246-273 2.77e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.77e-05
                           10        20
                   ....*....|....*....|....*...
gi 263190680   246 MLVVHMRRHTGEKPHKCTFegCRKSYSR 273
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 684-836 2.94e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 48.54  E-value: 2.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  684 PPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGP---PTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKAlgGTYS 760
Cdd:PRK10263  339 PVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPviaPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAA--EQPA 416

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 263190680  761 QCPRLEHYGQVQVKPEQGCPVGSDSTGLAPcLNAHPSEGPPHPQPLF---SHYPQPSPPQYLQSGPYTQPPPDYLPSEP 836
Cdd:PRK10263  417 QQPYYAPAPEQPAQQPYYAPAPEQPVAGNA-WQAEEQQSTFAPQSTYqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEP 494
PHA03247 PHA03247
large tegument protein UL36; Provisional
 470-829 9.12e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 9.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  470 PIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPglmpaqhyllr 549
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP----------- 2819

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  550 aryASARGGGTSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPTVA 629
Cdd:PHA03247 2820 ---PAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTE 2896

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  630 GGGQNFD-PYLPTSVYSPQPPSITENAAMDARGLQEEPEvgtsmvgSGLNPYMDFPPTDTLGYGGPEGAAAEPY-GARGP 707
Cdd:PHA03247 2897 SFALPPDqPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-------PPRPQPPLAPTTDPAGAGEPSGAVPQPWlGALVP 2969

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  708 GSLPL------GPGPPTNYGPNPCPQQASYPDPTQETWGE-FPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQgcP 780
Cdd:PHA03247 2970 GRVAVprfrvpQPAPSREAPASSTPPLTGHSLSRVSSWASsLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSD--S 3047

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 263190680  781 VGSDSTGLAPclnahpseGPPHPQPLFSHYPQPSPPQY-LQSGPYTQ--PPP 829
Cdd:PHA03247 3048 ERSDLEALDP--------LPPEPHDPFAHEPDPATPEAgARESPSSQfgPPP 3091
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
258-338 2.31e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.07  E-value: 2.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  258 KPHKCtfEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNaSDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSS 337
Cdd:COG5048    32 RPDSC--PNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSR-PLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108


                  .
gi 263190680  338 L 338
Cdd:COG5048   109 S 109
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
250-306 3.15e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.69  E-value: 3.15e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 263190680  250 HMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 306
Cdd:COG5048    52 HIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108
dnaA PRK14086
chromosomal replication initiator protein DnaA;
722-942 4.69e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 44.05  E-value: 4.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  722 PNPCPQQASYPDPTQETWGEFPSHSglYPGPKALggtysqcPRLEHYGQVQVKPEqgcpvgsdSTGLAPCLNAHPSEGPp 801
Cdd:PRK14086   96 APPPPHARRTSEPELPRPGRRPYEG--YGGPRAD-------DRPPGLPRQDQLPT--------ARPAYPAYQQRPEPGA- 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  802 HPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEP-RPCLDFDSPTHSTGQLKaqlvcnyvQSQQELLWEGGGREDAPAQ 880
Cdd:PRK14086  158 WPRAADDYGWQQQRLGFPPRAPYASPASYAPEQERdREPYDAGRPEYDQRRRD--------YDHPRPDWDRPRRDRTDRP 229

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 263190680  881 EPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSgSYPTPSPCH---------ENFVVGA-NRASH 942
Cdd:PRK14086  230 EPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPA-PAPGPGEPTarlnpkytfDTFVIGAsNRFAH 300
PHA03247 PHA03247
large tegument protein UL36; Provisional
 521-998 9.42e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 9.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  521 ASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASsldrigglPMPPWRSRAEYPGYNPNAgvtrrASD 600
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSAR--------PRAPVDDRGDPRGPAPPS-----PLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  601 PAQAA-DRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSgLNP 679
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS-LTS 2697

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  680 YMDFPPtdtlgyggPEGAAAEPYGARGPGsLPLGPGPPTNYGPNPCPQQASYPDPTQETwGEFPSHSGLYPGPKALGGTY 759
Cdd:PHA03247 2698 LADPPP--------PPPTPEPAPHALVSA-TPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPARPPTTAGPP 2767

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  760 SQCPrlehyGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPC 839
Cdd:PHA03247 2768 APAP-----PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  840 LDFDSPTHSTgqlkaqlvCNYVQSQQELLWEGGGREDAPA-QEPSYQSPKFLGGSQVSPSRAKAPVNTYGPgfgPNLPNH 918
Cdd:PHA03247 2843 PGPPPPSLPL--------GGSVAPGGDVRRRPPSRSPAAKpAAPARPPVRRLARPAVSRSTESFALPPDQP---ERPPQP 2911

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  919 KSGSYPTPSPCHENfvvgANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLggGPALYPPPEGQVCNPLDS 998
Cdd:PHA03247 2912 QAPPPPQPQPQPPP----PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL--VPGRVAVPRFRVPQPAPS 2985
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
234-341 1.53e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  234 CSRELRPFKAQYMLVVHMR--RHTGE--KPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAK 309
Cdd:COG5048   292 SKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNEP 371

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 263190680  310 HQ----NRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 341
Cdd:COG5048   372 PQslqqYKDLKNDKKSETLSNSCIRNFKRDSNLSLH 407
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
479-611 1.83e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  479 PSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGG 558
Cdd:PRK12323  365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 263190680  559 GTSPTAASSLdriggLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPA 611
Cdd:PRK12323  445 GGAPAPAPAP-----AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPA 492
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
155-392 1.96e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  155 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 227
Cdd:COG5236   117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  228 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 298
Cdd:COG5236   193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  299 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 357
Cdd:COG5236   258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 263190680  358 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 392
Cdd:COG5236   333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
187-323 8.46e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.06  E-value: 8.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  187 EPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGE-RKEFVCHWGGCSRelrPFKAQYMLVVHMRRHTGEKPHKCTFE 265
Cdd:COG5048   281 SSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEsLKPFSCPYSLCGK---LFSRNDALKRHILLHTSISPAKEKLL 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 263190680  266 GCRKSYSRLEN-----------------------------------LKTHLRSHTGEKPYMCEHEGCSKAFSNASDrAKH 310
Cdd:COG5048   358 NSSSKFSPLLNneppqslqqykdlkndkksetlsnscirnfkrdsnLSLHIITHLSFRPYNCKNPPCSKSFNRHYN-LIP 436

                         170
                  ....*....|...
gi 263190680  311 QNRTHSNEKPYVC 323
Cdd:COG5048   437 HKKIHTNHAPLLC 449
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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