|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
40-593 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1068.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 40 MAALTRDPQFQKLQQWYREHRsELNLRRLFDANKDRFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAA 119
Cdd:PRK00179 2 NINLTQTPAWQALQAHADEIK-DVHLRDLFAADPDRFERFSLTA----GGLLLDYSKNRITDETLALLLDLAREAGLEGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 120 RERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGS 199
Cdd:PRK00179 77 RDAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 200 DLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVA 279
Cdd:PRK00179 157 DLGPVMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 280 KHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLL 359
Cdd:PRK00179 237 KHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 360 ALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTK 439
Cdd:PRK00179 317 ALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 440 MIPCDFLIPVQTQHPIRKglHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFT 519
Cdd:PRK00179 397 LVPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLD 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 577019448 520 KLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQRE 593
Cdd:PRK00179 475 RLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
93-585 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 973.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 93 DYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFC 172
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 173 QRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTF 252
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 253 TTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNF 332
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 333 EQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDH 412
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 413 QTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPiRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAg 492
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNP-ENGDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 493 kspeDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSA 572
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 577019448 573 QVTSHDASTNGLI 585
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
75-590 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 768.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 75 RFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSrgvEAARERMFNGEKINYTEGRAVLHVALRNRSntpilvDG 154
Cdd:COG0166 12 RFERFSLEA----AGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEKINPTEGRAVLHGALRLPE------AG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 155 KDVMPEVNKVLDKMKSFCQRVRsgdwkgyTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKT 234
Cdd:COG0166 79 EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAEL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 235 LAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDpsAVAKHFVALSTNTTKVKEFGIDP-QNMFEFWDWVGGRY 313
Cdd:COG0166 152 LAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDWVGGRY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 314 SLWSAIGLSIALHVGFDnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQ 393
Cdd:COG0166 230 SVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 394 GDMESNGKYITKSGTRVDHQTGPIvwGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIrkglhHKILLANFlaQTE 473
Cdd:COG0166 309 LWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI-----PDLLLANL--QGL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 474 ALMRGKSTEEARK-ELQAAgkspedlerllPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQW 552
Cdd:COG0166 380 ALLAGKTLDEVLAlAAEAT-----------PHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQP 448
|
490 500 510
....*....|....*....|....*....|....*...
gi 577019448 553 GVELGKQLAKKIEPELDGSAQVTshDASTNGLINFIKQ 590
Cdd:COG0166 449 GVELGKKLAFALLGKLGGEEAAA--GDSTEALLKRLRA 484
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
373-564 |
1.81e-91 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 278.71 E-value: 1.81e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 373 ETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTrvDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 452
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGE--DYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 453 H----PIRKGLHHKILLANFLAQTEALMrgksteearkelqaagkspedlerllphkvFEGNRPTNSIVFTKLTPFMLGA 528
Cdd:cd05016 79 NdvldYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 577019448 529 LVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 564
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
40-593 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1068.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 40 MAALTRDPQFQKLQQWYREHRsELNLRRLFDANKDRFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAA 119
Cdd:PRK00179 2 NINLTQTPAWQALQAHADEIK-DVHLRDLFAADPDRFERFSLTA----GGLLLDYSKNRITDETLALLLDLAREAGLEGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 120 RERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGS 199
Cdd:PRK00179 77 RDAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 200 DLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVA 279
Cdd:PRK00179 157 DLGPVMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 280 KHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLL 359
Cdd:PRK00179 237 KHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 360 ALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTK 439
Cdd:PRK00179 317 ALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 440 MIPCDFLIPVQTQHPIRKglHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFT 519
Cdd:PRK00179 397 LVPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLD 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 577019448 520 KLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQRE 593
Cdd:PRK00179 475 RLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
93-585 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 973.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 93 DYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFC 172
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 173 QRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTF 252
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 253 TTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNF 332
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 333 EQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDH 412
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 413 QTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPiRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAg 492
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNP-ENGDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 493 kspeDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSA 572
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 577019448 573 QVTSHDASTNGLI 585
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
75-590 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 768.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 75 RFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSrgvEAARERMFNGEKINYTEGRAVLHVALRNRSntpilvDG 154
Cdd:COG0166 12 RFERFSLEA----AGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEKINPTEGRAVLHGALRLPE------AG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 155 KDVMPEVNKVLDKMKSFCQRVRsgdwkgyTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKT 234
Cdd:COG0166 79 EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAEL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 235 LAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDpsAVAKHFVALSTNTTKVKEFGIDP-QNMFEFWDWVGGRY 313
Cdd:COG0166 152 LAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDWVGGRY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 314 SLWSAIGLSIALHVGFDnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQ 393
Cdd:COG0166 230 SVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 394 GDMESNGKYITKSGTRVDHQTGPIvwGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIrkglhHKILLANFlaQTE 473
Cdd:COG0166 309 LWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI-----PDLLLANL--QGL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 474 ALMRGKSTEEARK-ELQAAgkspedlerllPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQW 552
Cdd:COG0166 380 ALLAGKTLDEVLAlAAEAT-----------PHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQP 448
|
490 500 510
....*....|....*....|....*....|....*...
gi 577019448 553 GVELGKQLAKKIEPELDGSAQVTshDASTNGLINFIKQ 590
Cdd:COG0166 449 GVELGKKLAFALLGKLGGEEAAA--GDSTEALLKRLRA 484
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
38-586 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 733.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 38 PAMAALTRDPQFQKLQQWYrEHRSELNLRRLFdANKDRFNHFSLTLNTnhghILVDYSKNLVTEDVMRMLVDLAKSRGVE 117
Cdd:PLN02649 3 KKTLLISDTPAWKRLVAHV-YQIKKTHLRELL-NDAERCQSMIAEFDG----IYLDYSRQRVTDETMELLFPLAEAANLF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 118 AARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIG 197
Cdd:PLN02649 77 EKIEAMFSGEIINSTEDRAVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 198 GSDLGPLMVTEALKPY-----SSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAA 272
Cdd:PLN02649 157 GSFLGPLFVHEALATDpealkSAKGRKLRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRDAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 273 kDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIG-LSIALHVGFDNFEQLLSGAHWMDQHFRTTPL 351
Cdd:PLN02649 237 -GGLAVAKHMVAVSTNLLLVNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRTAPL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 352 EKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFY 431
Cdd:PLN02649 316 KENIPVLLGLLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQHSFY 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 432 QLIHQGtKMIPCDFLIPVQTQHPIRKGL-----HHKILLANFLAQTEALMRGKSTEEARKElqaagkspEDLERLLPHKV 506
Cdd:PLN02649 396 QLIHQG-RNIPCDFIGVVRSQQPVHLWLgegvsNHDELMSNFFAQPDALAYGKTPEQLRAE--------GVPEELIPHKV 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 507 FEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGS----AQVTSHDASTN 582
Cdd:PLN02649 467 FAGNRPSLSILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNEArtkgEPVEGFNSSTT 546
|
....
gi 577019448 583 GLIN 586
Cdd:PLN02649 547 ALLN 550
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
42-564 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 617.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 42 ALTRDPQFQKLQQwYREHRSELNLRRLFDaNKDRFNHfsltLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARE 121
Cdd:PTZ00430 2 DLESLKSYKNLLS-LAEKLKKVHLRDLLK-DEERNKS----LIKEFKGVTLDLSRQRLDEETLKLLIELAEEAKLKEKIK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 122 RMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDL 201
Cdd:PTZ00430 76 DMFNGEKINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLDRIKKFSDKIRSGEILGSTGKKLKNVICIGIGGSYL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 202 GPLMVTEALKPYSSG-----GPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPS 276
Cdd:PTZ00430 156 GTEFVYEALRTYGEAreaskGRKLRFLANVDPIDVRRATEGLDPEETLVVIISKTFTTAETMLNAKTVRQWLLDNIKSKE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 277 AVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIG-LSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNA 355
Cdd:PTZ00430 236 ALSKHLCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGiLPLSIQFGYDIVQQFLNGCHDMDEHFRTAPLEENL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 356 PVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIH 435
Cdd:PTZ00430 316 PVLLGLTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNGKSVTLDGNTLDYNTGEIYFGEPGTNGQHSFYQLLH 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 436 QGTkMIPCDFLIPVQTQHPIRKG----LHHKILLANFLAQTEALMRGKSTEEARKElqaaGKSPEdlerLLPHKVFEGNR 511
Cdd:PTZ00430 396 QGR-VVPSEFIGFAKSQNPIKLLgepvSNHDELMSNFFAQPDALAFGKTYEELEKE----GVPEE----LIPHKVFPGNR 466
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 577019448 512 PTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 564
Cdd:PTZ00430 467 PSLLLLFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVELGKVLAKDV 519
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
49-564 |
7.17e-143 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 424.43 E-value: 7.17e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 49 FQKLQQWyreHRSELNLRRLFDANKDRFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEK 128
Cdd:PRK14095 13 FKILQEL---APEPLDLTLPGVLSEERIKKYSLSG----EGFTYNYATERVDDRILAALQNLADEAELIEKMKAMQNGAV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 129 INYTEG-----RAVLHVALRNRSNTPILVDGKDVMPEVNKV-LDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLG 202
Cdd:PRK14095 86 INRIEGfpsenRPVLHTATRGQVGDSVLTDEAEDMAEFSKReLERLAEFLKKVRSGEIKNSNGKKFTTVVQIGIGGSDLG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 203 PLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPsavAKHF 282
Cdd:PRK14095 166 PKALYLALKNYAKKDKRVHFISNVDPDDAAEVLSEIDLAKTLFIVVSKSGTTLETAANEEFVRDALKKAGLDY---KKHF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 283 VALSTNTTKVKefgiDPQN---MFEFWDWVGGRYSLWSAIGLS-IALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVL 358
Cdd:PRK14095 243 IAVTSEGSPMD----DESGyleVFHMWDSIGGRFSSTSMVGGVvLGFAFGFEVFKEFLKGAAAMDKAALNPNIRENLPLL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 359 LALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGT 438
Cdd:PRK14095 319 AALIGIWNRNFLGYPTTAVIPYSQALERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGTNGQHSFFQLLHQGT 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 439 KMIPCDFLIPVQTQH----PIRKGLHHKILLANFLAQTEALMRGKSTEEarkelqaagkspedlerllPHKVFEGNRPTN 514
Cdd:PRK14095 399 DIVPVEFIGFKESQLgqdiVIQGSTSQQKLFANLIAQIIALACGKENTN-------------------PNKNFKGNRPSS 459
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 577019448 515 SIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 564
Cdd:PRK14095 460 LLVAKQLTPYTLGALLAHYENKVMFQGFCWNINSFDQEGVQLGKVLANQI 509
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
373-564 |
1.81e-91 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 278.71 E-value: 1.81e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 373 ETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTrvDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 452
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGE--DYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 453 H----PIRKGLHHKILLANFLAQTEALMrgksteearkelqaagkspedlerllphkvFEGNRPTNSIVFTKLTPFMLGA 528
Cdd:cd05016 79 NdvldYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 577019448 529 LVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 564
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
162-325 |
1.78e-82 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 255.14 E-value: 1.78e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 162 NKVLDKMKSFCQRVRSGdwkgytgKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPE 241
Cdd:cd05015 1 RAELERIKEFAEKVRSG-------KKITDVVVIGIGGSDLGPRAVYEALKPYFKGGLRLHFVSNVDPDDLAELLKKLDPE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 242 SSLFIIASKTFTTQETITNAETAKEWFLQAAKDpsAVAKHFVALSTNTTKVKE-FGIDPQNMFEFWDWVGGRYS-LWSAI 319
Cdd:cd05015 74 TTLFIVISKSGTTLETLANARLAREWLEEAGGD--DLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWVGGRFSvLSSVG 151
|
....*.
gi 577019448 320 GLSIAL 325
Cdd:cd05015 152 GLPLAL 157
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
102-564 |
2.23e-50 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 182.01 E-value: 2.23e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 102 DVMRMLVDLAKSRGVEAARERMF-------NGEKINYTEGRAVLHVALRNrsntPILVDGKDVMPEVNKVLDKMKSFCQR 174
Cdd:PRK14096 25 DISRMNFDDAFLESLEPKFQKAFaamaaleAGAIANPDEGRMVGHYWLRN----PELAPTPEIRAEITETLAQIEAFAAK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 175 VRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPySSGGPRVWYVSNIDGTHIAKTLAQLNPE--SSLFIIASKTF 252
Cdd:PRK14096 101 VHSGTIKPPNGEKFTDVLWIGIGGSALGPQFVAEALQP-NSDGLNIHFIDNTDPDGIDRVLAELGDRlaTTLVVVISKSG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 253 TTQETITNAETAKEWFLQAAKDpsaVAKHFVALSTNTTKVKEFGIDPQ--NMFEFWDWVGGRYSLWSAIGLSIALHVGFD 330
Cdd:PRK14096 180 GTPETRNGMLEAKAAYEAAGLD---FASHAVAITMKGSKLDQLAQSEGwlARFPMWDWVGGRTSETSAVGLLPAALQGID 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 331 NFEqLLSGAHWMDQHFRTTPLEKNAPVLLALLgiWYINCFGCETHAM--LPYDQYLHRFAAYFQQGDMESNGKYITKSGT 408
Cdd:PRK14096 257 IRA-FLAGAKQMDEATRVPDLKNNPAALLALA--WYYAGDGKGKKDMvvLPYKDRLLLFSRYLQQLVMESLGKELDLDGN 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 409 RVdHQtGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFL----IPVQTQHPIRKGLHHKILLANFLAQT-EALmrgkstee 483
Cdd:PRK14096 334 VV-HQ-GIAVYGNKGSTDQHAYVQQLRDGVDNFFVTFIevleDRQGSSIEVEPGVTSGDYLSGFLQGTrQAL-------- 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 484 arkelqaagkspedlerllphkvFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKK 563
Cdd:PRK14096 404 -----------------------YENGRQSITITIPEVNPRTLGALIALFERAVGLYASLVNINAYHQPGVEAGKKAAAA 460
|
.
gi 577019448 564 I 564
Cdd:PRK14096 461 I 461
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
186-561 |
1.79e-37 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 144.37 E-value: 1.79e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 186 KTITDVINIGIGGSDLGPLMVTEALKPYSS--------GGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQET 257
Cdd:PRK00973 69 KNFDNVVVLGIGGSALGNLALHYALNPLNWnelskeerNGPRVFVLDNVDPEKTASILDVIDLEKTLFNVISKSGNTAET 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 258 ITNAETAKEWFLQAAKDPSavaKHFVALsTNTTK------VKEFGID----PQNmfefwdwVGGRYSLWSAIGLSIALHV 327
Cdd:PRK00973 149 LANYLIIRGILEKLGLDPK---KHLVFT-TDPEKgklkkiAEKEGYRtleiPEN-------VGGRFSVLTPVGLAPAAAL 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 328 GFDnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINcFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKyitksg 407
Cdd:PRK00973 218 GID-IEELLEGAKEMDKICEKEDIFKNPALLNALIHYLYYN-RGKNISVMMPYSERLKYFGDWYRQLWAESLGK------ 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 408 tRVDHQTgPIvwGEPGTNGQHAFYQLIHQG--TKMI--------PCDFLIPvqTQHPIRKGLHH---KILlaNFLAQTEA 474
Cdd:PRK00973 290 -KGVGQT-PV--KALGATDQHSQLQLYMEGpkDKIItflkvekyRRDVEIP--YEYEDIEELSYlggHKL--SELINSEQ 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 475 lmrgKSTEEARKelqaagkspedlerllphkvfEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGV 554
Cdd:PRK00973 362 ----KGTEIALT---------------------ENGRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGV 416
|
....*..
gi 577019448 555 ELGKQLA 561
Cdd:PRK00973 417 ELGKKIT 423
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
186-564 |
9.36e-28 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 115.80 E-value: 9.36e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 186 KTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAK 265
Cdd:PRK03868 56 ESIKNIVVIGIGGSSLGVKAIYSFLKNEKNNKKELHFLENTDPISINKTLSKINLENTLFIVISKSGTTIETISIFKYLL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 266 EWF--LQAAK-------DPSAVAKHFvalsTNTTKVKEFGIdPQNmfefwdwVGGRYSLWSAIG---LSIAlhvGFDnFE 333
Cdd:PRK03868 136 SHFklDQELKknflfitDPDSKLEQF----AKENNIKCFNI-PKN-------VGGRFSVLSAVGivpLALC---GYD-IK 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 334 QLLSGAHWMDQHFrttpLEKNAPVLL--ALLGIWYINCFgcETHAMLPYDQYLHRFAAYFQQGDMESNGKyITKSGTRVd 411
Cdd:PRK03868 200 ALLEGAKACKDSF----FEQKEDHILkkAYFYATHKNAY--NINVLFSYSDALKGFNDWYVQLWGESLGK-KQGYKTRV- 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 412 hqtGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIR------KGLhHKILLANFLAQTEAL-MRGKSTEEA 484
Cdd:PRK03868 272 ---GLTPIGLIGSRDQHSFLQLIMEGPRDKTVTFIKIKDFQNAPKipnislKGL-ESLDFVNGVSFNELInAQCDATMEA 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 485 RKElqaagkspEDLerllphkvfegnrPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 564
Cdd:PRK03868 348 LIA--------EDI-------------PVDVITLEKLDEFSIGYLIYYYELLTSAVGKMLGINTYDQPGVEVGKRILKEK 406
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
189-559 |
4.68e-11 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 65.25 E-value: 4.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 189 TDVINIGIGGSDLGPLMVTEAL--------KPYSSGGPRVWYVSN-IDGTHIAKTLAQL-NPESSLFIIaSKTFTTQET- 257
Cdd:PRK14097 74 DVLVVIGIGGSYLGARAAIEFLnhsfynllPKEQRKAPQIIFAGNsISSTYLADLLEYLkDKDFSINVI-SKSGTTTEPa 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 258 ----ITNAETAKEWFLQAAKdpsavaKHFVAlSTNTTK--VKEFGiDPQN--MFEFWDWVGGRYSLWSAIGLSIALHVGF 329
Cdd:PRK14097 153 iafrIFKELLEKKYGKEEAK------KRIYA-TTDKAKgaLKTLA-DAEGyeTFVIPDDVGGRFSVLTAVGLLPIAVAGI 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 330 DnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINcFGCETHAMLPYDQYLHRFAAYFQQGDMESNGK-----YIT 404
Cdd:PRK14097 225 D-IDALMKGAADARKDYSSSDLSENPAYQYAAVRNILYR-KGYTTEILVNYEPSLQYFSEWWKQLFGESEGKdqkgiFPA 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 405 KSGTRVD-HQTGpivwgepgtngqhafyQLIHQGTKMIpcdFLIPVQTQHPirkglHHKILLA---------NFLAqtea 474
Cdd:PRK14097 303 SANFSTDlHSLG----------------QYIQEGRRNL---FETVIKVEKP-----RKDLTIPedeedldglNYLA---- 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 475 lmrGKSTEEA-RKELQAAgkspedlerLLPHkvFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWG 553
Cdd:PRK14097 355 ---GKTVDFVnKKAFEGT---------LLAH--TDGGVPNIVVNIPELDEYTFGYLVYFFEKACAISGYLLGVNPFDQPG 420
|
....*.
gi 577019448 554 VELGKQ 559
Cdd:PRK14097 421 VEAYKK 426
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
165-342 |
1.73e-10 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 64.22 E-value: 1.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 165 LDKMKSFCQRVRSGDwkgytgktITDVINIGIGGSDLGPlmvtEALK---PYSSGGPRVwYVsnIDGTHIAKTLA---QL 238
Cdd:PRK09533 440 LAEYEAFAEEVRAEG--------FTDAVVLGMGGSSLGP----EVLAetfGQRDGFPKL-HV--LDSTDPAQVRAleaAV 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 239 NPESSLFIIASKTFTTQEtiTNAetAKEWFLQAAKDP--SAVAKHFVALS---TNTTKVKE-------FGIDPQnmfefw 306
Cdd:PRK09533 505 DLARTLFIVSSKSGGTLE--PNI--FKDYFFARVKEVlgAKAGRHFVAVTdpgSSLEKVAKedgfrkiFHGDPD------ 574
|
170 180 190
....*....|....*....|....*....|....*.
gi 577019448 307 dwVGGRYSLWSAIGLSIALHVGFDnFEQLLSGAHWM 342
Cdd:PRK09533 575 --IGGRYSVLSPFGLVPAAAAGID-VRALLDSALAM 607
|
|
| SIS |
cd04795 |
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
383-475 |
1.15e-03 |
|
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240112 [Multi-domain] Cd Length: 87 Bit Score: 38.12 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577019448 383 YLHRFAAYFQQGDMESngkyitksgtrvdhqTGPIVWGEPGTNGQHAFyqLIHQGTKMIPCDFLIPVQTQhpirkglhhk 462
Cdd:cd04795 8 GSGAIAAYFALELLEL---------------TGIEVVALIATELEHAS--LLSLLRKGDVVIALSYSGRT---------- 60
|
90
....*....|...
gi 577019448 463 ILLANFLAQTEAL 475
Cdd:cd04795 61 EELLAALEIAKEL 73
|
|
| SIS_1 |
cd05710 |
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar ... |
194-266 |
7.93e-03 |
|
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240214 [Multi-domain] Cd Length: 120 Bit Score: 36.79 E-value: 7.93e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 577019448 194 IGIGGSdLGPLM-VTEALKPYSSggpRVWYVSNidgthiAKTLAQLNP----ESSLFIIASKTFTTQETITNAETAKE 266
Cdd:cd05710 5 VGCGGS-LADMYpAKYFLKKESK---LPVFVYN------AAEFLHTGPkrltEKSVVILASHSGNTKETVAAAKFAKE 72
|
|
| |
