|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
134-339 |
1.43e-106 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 321.83 E-value: 1.43e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 134 FSKVCVNEEGIQKLQRAIQE-HPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMkMVGELLRMSGAFFMRRT 212
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 213 FGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETL 292
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 7657134 293 YVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLAA 339
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
75-644 |
9.22e-105 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 334.20 E-value: 9.22e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 75 VLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNeeGIQKLQRAIQEH 154
Cdd:COG2937 126 LLRSPAVRKAIEEEAKSKGISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD--NLERLRELAKGH 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 155 PVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAG--MDFLGmkmVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLR 232
Cdd:COG2937 204 EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAGinLNFWP---LGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFE 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 233 NGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLK 312
Cdd:COG2937 281 RGY-SVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLR 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 313 ARKILSENFGSIHVYFGDPVSLRSLAAgrmsrsSYNLVPRYIPQKQSEDMHAFVTEVAYK-MEllQIEN-MVLSPWTLIV 390
Cdd:COG2937 360 ALRKLRRRFGRVYVNFGEPISLSEYLD------QHVPDWRESEDLRPEWLRPAVDKLAFEiMV--RINRaAAVNPVNLVA 431
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 391 AVLLQNRP-SMDFDALVEKTLWLKGLTQAFGGfliwPDNKPAEEVVPASILLHsniasLVKDQVILKVDSGDSEVVdglM 469
Cdd:COG2937 432 LALLASPKrALTEAELLAQLDLYLDLLRNVPY----SLSVTLPELTPEELLEH-----LLSLGLIEVEKDGLGDVI---S 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 470 L---QHITLlmcSAYRNQLLNIFVRPSLVAVALQMTPGFRKEDVYSCFRFLRDVFADEFIFLPGNTLKD-FEEGCYLLCK 545
Cdd:COG2937 500 IddeQAVLL---TYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVR 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 546 SEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSS 625
Cdd:COG2937 577 QGLLEREGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLGSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDK 656
|
570
....*....|....*....
gi 7657134 626 DVQKNALAACVRLGVVEKK 644
Cdd:COG2937 657 ALFRNFIQTLREQGYLDDD 675
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
62-608 |
5.26e-74 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 258.65 E-value: 5.26e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 62 GITPckpiDIKCSVLNSEEIHYVIKQLS-KESLQSVDVLREEVSeILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVN 140
Cdd:PTZ00374 539 GLTP----ESLTSILAQPSIQRLMTALAkKEGASEKDVEARAKA-ILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLN 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 141 EEGIQKLQRAIQEhP---VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNK 217
Cdd:PTZ00374 614 SGAFERLHRYVAM-PrvaVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMGPIATLMRGSGAFFMRRSFRDDP 692
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 218 LYWAVFSEYVKTMLRnGYAPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFF--KREVFDTYLVPISISYDKILEETLYVY 295
Cdd:PTZ00374 693 LYAALFKEYVRHLVL-RRRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELDDVLIIPVSLSYDELLETTLYAK 771
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 296 ELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLA-------------AGRMSRSSYNL--------VPRYI 354
Cdd:PTZ00374 772 EQLGVSKPKENPGNLLRARSLLKRRHGKIHVHIGEPVSLRSFKdhplqcplpfepkGEATTSVCKTLdttpsiarKSSIT 851
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 355 PQKqsedmhaFVTEVAYK-MELLQiENMVLSPWTLIVAVLLQNRPS---MDFDALVEKTLWLKGLTQAFGGFL-IWPDNK 429
Cdd:PTZ00374 852 PPR-------VLTNIAWHlTHKLQ-RNTIITPTALVAAVLECLGPTagaMPLAEVQQGMTWLRTNIRRRGAALsDDCANL 923
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 430 PAEEVVPASIllhSNIASLVKdqvILKVDSGDSEVVDGLMlQHITLLMCSayrNQLLNIFVRPSLVAVALQM-----TPG 504
Cdd:PTZ00374 924 NPETMVRKAL---THLQEFVE---ITDEMSEVIYVRQDVV-TRLGVNICS---NQLIHVFMDEAVVAVVARAfgevtAPH 993
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 505 FR---KEDVYS--CfRFLRDVFADEFiflpgntlKDFEEGC------YLLCKSEAIQVTTKDIL-VTEKGNTVLEFLVGL 572
Cdd:PTZ00374 994 RVrrvEADVLKeqC-QLLRQLLSAEF--------QDYLPACpytfasWHGLELKPVAKEAAYTIpATADRTVLLERLQQL 1064
|
570 580 590
....*....|....*....|....*....|....*....
gi 7657134 573 FKPFVESYQIICKYLLSEEEDHFSE---EQYLAAVRKFT 608
Cdd:PTZ00374 1065 MRHVCEMRSSSPHLLRAEEQKKAREdilKEYVKVLRRMK 1103
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
74-496 |
8.62e-60 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 215.10 E-value: 8.62e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 74 SVLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCV-NEEGIQKLqrAIQ 152
Cdd:PRK04974 223 KLLASPAIKKAIEDEAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQD 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 153 EHPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDfLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLR 232
Cdd:PRK04974 301 GHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFA 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 233 NGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLK 312
Cdd:PRK04974 380 RGY-SVEYFVEGGRSRTGRLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLR 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 313 ARKILSeNFGSIHVYFGDPVSLRSLAAGRM--SRSSYNLVPRYIPQKqsedMHAFVTEVAYKMeLLQIEN-MVLSPWTLI 389
Cdd:PRK04974 459 GIRKLR-NFGQGYVNFGEPIPLNDYLNQHVpeWRESIDPIEEQRPAW----LTPAVNNLANQV-MVRINNaAAANPVNLC 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 390 VAVLLQNRP-SMDFDALVEK-TLWLKGLTQA-FGGFLIWPDNKPAEevvpasILLHS---NIASLVKDQV--ILKVDsgD 461
Cdd:PRK04974 533 ALALLASRQrALDREQLIEQlDLYLQLLRNVpYSSDTTVPEGSGEE------LIDHAlslNKFEVEKDTLgdIISLD--R 604
|
410 420 430
....*....|....*....|....*....|....*
gi 7657134 462 SEVVdgLMlqhitllmcSAYRNQLLNIFVRPSLVA 496
Cdd:PRK04974 605 EQAV--LM---------TYYRNNILHLFVLPSLIA 628
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
138-283 |
1.16e-30 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 116.61 E-value: 1.16e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 138 CVNEEGIQKLQRaiqEHPVVLLPSHRSYIDFLMLSFLLYNYDLPvPVIAAGMDFLGMKMVGELLRMSGAFFMRRtfgGNK 217
Cdd:pfam01553 1 RIEVHGLENLPR---GGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7657134 218 LYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISIS 283
Cdd:pfam01553 74 KDAAGTLEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
156-285 |
1.26e-22 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 93.57 E-value: 1.26e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 156 VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLgMKMVGELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRNGY 235
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 7657134 236 aPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPffkrevfDTYLVPISISYD 285
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
293-582 |
4.72e-17 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 83.34 E-value: 4.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 293 YVYELLGVPKPKESTTGLLK-ARKILSENFGSIHVYFGDPVSLRSLAAGRMSRSSYnlvpryipqkQSEDMHAFVTEVAY 371
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLREFLDEQGDRPAT----------DAARRRLALQKLAF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 372 KMeLLQI-ENMVLSPWTLIVAVLLQNRP-SMDFDALVEKTLWL------KGLTQAFGGFLiwpdnkPAEEVVPASillhs 443
Cdd:pfam19277 71 EV-LSRInRVTPVMPTALVGTVLLTLRGrALTLSELIRRVEWLldyiraRGGPVAHFGDL------RTEEVVDRA----- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 444 nIASLVKDQVILKVDSGDSEV-----VDGLMLqhitllmcSAYRNQLLNIFVRPSLVAVALQMTP-----GFRKEDVYSC 513
Cdd:pfam19277 139 -LDVLGNAGLVTRVDGGPEPVyyiapEDHFQA--------SFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALWDQ 209
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 514 FRFLRDVFADEFIFLPGNTLK-DFEEGCYLLCKSEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQI 582
Cdd:pfam19277 210 VLRLRDLLKFEFFFPPKEGFReNLRAELDLLDPWEDRVITGERDIERLLGRENPDFACFLLWPFIEAYWL 279
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
152-338 |
3.06e-10 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 60.41 E-value: 3.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 152 QEHPVVLLPSHRSYIDFLMLSFLlynydLPVPV-IAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLywAVFsEYVKTM 230
Cdd:COG0204 41 ADGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 231 LRNGYAPVeFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISISYdkileeTLYVYELLGVPKPkesttgl 310
Cdd:COG0204 113 LKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE-------AGVPIVPVAIDG------TERALPKGFLPRP------- 171
|
170 180
....*....|....*....|....*...
gi 7657134 311 lkarkilsenfGSIHVYFGDPVSLRSLA 338
Cdd:COG0204 172 -----------GKVTVRIGPPIDPSDLE 188
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
134-339 |
1.43e-106 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 321.83 E-value: 1.43e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 134 FSKVCVNEEGIQKLQRAIQE-HPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMkMVGELLRMSGAFFMRRT 212
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 213 FGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETL 292
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 7657134 293 YVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLAA 339
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
75-644 |
9.22e-105 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 334.20 E-value: 9.22e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 75 VLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNeeGIQKLQRAIQEH 154
Cdd:COG2937 126 LLRSPAVRKAIEEEAKSKGISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD--NLERLRELAKGH 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 155 PVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAG--MDFLGmkmVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLR 232
Cdd:COG2937 204 EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAGinLNFWP---LGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFE 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 233 NGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLK 312
Cdd:COG2937 281 RGY-SVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLR 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 313 ARKILSENFGSIHVYFGDPVSLRSLAAgrmsrsSYNLVPRYIPQKQSEDMHAFVTEVAYK-MEllQIEN-MVLSPWTLIV 390
Cdd:COG2937 360 ALRKLRRRFGRVYVNFGEPISLSEYLD------QHVPDWRESEDLRPEWLRPAVDKLAFEiMV--RINRaAAVNPVNLVA 431
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 391 AVLLQNRP-SMDFDALVEKTLWLKGLTQAFGGfliwPDNKPAEEVVPASILLHsniasLVKDQVILKVDSGDSEVVdglM 469
Cdd:COG2937 432 LALLASPKrALTEAELLAQLDLYLDLLRNVPY----SLSVTLPELTPEELLEH-----LLSLGLIEVEKDGLGDVI---S 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 470 L---QHITLlmcSAYRNQLLNIFVRPSLVAVALQMTPGFRKEDVYSCFRFLRDVFADEFIFLPGNTLKD-FEEGCYLLCK 545
Cdd:COG2937 500 IddeQAVLL---TYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVR 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 546 SEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSS 625
Cdd:COG2937 577 QGLLEREGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLGSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDK 656
|
570
....*....|....*....
gi 7657134 626 DVQKNALAACVRLGVVEKK 644
Cdd:COG2937 657 ALFRNFIQTLREQGYLDDD 675
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
62-608 |
5.26e-74 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 258.65 E-value: 5.26e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 62 GITPckpiDIKCSVLNSEEIHYVIKQLS-KESLQSVDVLREEVSeILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVN 140
Cdd:PTZ00374 539 GLTP----ESLTSILAQPSIQRLMTALAkKEGASEKDVEARAKA-ILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLN 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 141 EEGIQKLQRAIQEhP---VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNK 217
Cdd:PTZ00374 614 SGAFERLHRYVAM-PrvaVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMGPIATLMRGSGAFFMRRSFRDDP 692
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 218 LYWAVFSEYVKTMLRnGYAPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFF--KREVFDTYLVPISISYDKILEETLYVY 295
Cdd:PTZ00374 693 LYAALFKEYVRHLVL-RRRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELDDVLIIPVSLSYDELLETTLYAK 771
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 296 ELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLA-------------AGRMSRSSYNL--------VPRYI 354
Cdd:PTZ00374 772 EQLGVSKPKENPGNLLRARSLLKRRHGKIHVHIGEPVSLRSFKdhplqcplpfepkGEATTSVCKTLdttpsiarKSSIT 851
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 355 PQKqsedmhaFVTEVAYK-MELLQiENMVLSPWTLIVAVLLQNRPS---MDFDALVEKTLWLKGLTQAFGGFL-IWPDNK 429
Cdd:PTZ00374 852 PPR-------VLTNIAWHlTHKLQ-RNTIITPTALVAAVLECLGPTagaMPLAEVQQGMTWLRTNIRRRGAALsDDCANL 923
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 430 PAEEVVPASIllhSNIASLVKdqvILKVDSGDSEVVDGLMlQHITLLMCSayrNQLLNIFVRPSLVAVALQM-----TPG 504
Cdd:PTZ00374 924 NPETMVRKAL---THLQEFVE---ITDEMSEVIYVRQDVV-TRLGVNICS---NQLIHVFMDEAVVAVVARAfgevtAPH 993
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 505 FR---KEDVYS--CfRFLRDVFADEFiflpgntlKDFEEGC------YLLCKSEAIQVTTKDIL-VTEKGNTVLEFLVGL 572
Cdd:PTZ00374 994 RVrrvEADVLKeqC-QLLRQLLSAEF--------QDYLPACpytfasWHGLELKPVAKEAAYTIpATADRTVLLERLQQL 1064
|
570 580 590
....*....|....*....|....*....|....*....
gi 7657134 573 FKPFVESYQIICKYLLSEEEDHFSE---EQYLAAVRKFT 608
Cdd:PTZ00374 1065 MRHVCEMRSSSPHLLRAEEQKKAREdilKEYVKVLRRMK 1103
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
74-496 |
8.62e-60 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 215.10 E-value: 8.62e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 74 SVLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCV-NEEGIQKLqrAIQ 152
Cdd:PRK04974 223 KLLASPAIKKAIEDEAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQD 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 153 EHPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDfLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLR 232
Cdd:PRK04974 301 GHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFA 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 233 NGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLK 312
Cdd:PRK04974 380 RGY-SVEYFVEGGRSRTGRLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLR 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 313 ARKILSeNFGSIHVYFGDPVSLRSLAAGRM--SRSSYNLVPRYIPQKqsedMHAFVTEVAYKMeLLQIEN-MVLSPWTLI 389
Cdd:PRK04974 459 GIRKLR-NFGQGYVNFGEPIPLNDYLNQHVpeWRESIDPIEEQRPAW----LTPAVNNLANQV-MVRINNaAAANPVNLC 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 390 VAVLLQNRP-SMDFDALVEK-TLWLKGLTQA-FGGFLIWPDNKPAEevvpasILLHS---NIASLVKDQV--ILKVDsgD 461
Cdd:PRK04974 533 ALALLASRQrALDREQLIEQlDLYLQLLRNVpYSSDTTVPEGSGEE------LIDHAlslNKFEVEKDTLgdIISLD--R 604
|
410 420 430
....*....|....*....|....*....|....*
gi 7657134 462 SEVVdgLMlqhitllmcSAYRNQLLNIFVRPSLVA 496
Cdd:PRK04974 605 EQAV--LM---------TYYRNNILHLFVLPSLIA 628
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
71-642 |
8.26e-46 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 174.51 E-value: 8.26e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 71 IKCSVLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMShklrLGAIRFcAFTLSKVFKQIFS-----KVCVNEEGIQ 145
Cdd:PRK03355 184 VKPEILASARFRAGLAKIAAKLGRPPGATVREAGKMLDELV----AGWSRV-SVDLVSVLGRLFSrgfdpEIDYDEYELA 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 146 KLQRAIQEHPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDfLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSE 225
Cdd:PRK03355 259 ALRALLEEHPAVLLFSHRSYIDGLVVPVAMQENRLPPVHVFGGIN-LSFGPMGPIMRRSGMIFIRRNIGDDPLYKYVLRE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 226 YVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKE 305
Cdd:PRK03355 338 YVGYLVEKRF-NLSWYIEGTRSRTGKLLPPKLGLLSYVADAYLDGRSDDVLLQPVSISFDQLHEIGEYAAEARGGEKTPE 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 306 STTGLLKARKILSE-NFGSIHVYFGDPVSLRS-LAAGRMSRSSYNLVPRYIPQKQsedmhAFvtEVAYkmELLQIENMVL 383
Cdd:PRK03355 417 GLRWLYNYIKAQGErNYGKIYVRFGEPVSMRQyLGAPHGPLTQDPDAKRLALQKM-----AF--EVAW--RINQVTPVTA 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 384 SpwTLIVAVLLQNRPsmdfdalveKTLWLKGLTQAFGGFLIW------PDNKPA-----EEVVPASILLHSNiaslvkDQ 452
Cdd:PRK03355 488 T--SLVSLLLLGTRG---------RALTLDELHHTLQDSLDYlerrqlPVSTSAlrlrdPEGVRAALDALSN------GG 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 453 VILKVDSGDSEVVDGLMLQHitlLMCSAYRNQLLNIFVRPSLVAVALQMTPGFRKEDVYSCF-----RfLRDVFADEFIF 527
Cdd:PRK03355 551 PVTRVDSGREPVWYIAPDDH---LVAAFYRNSVIHAFLERAIVELALAAAAHVDEGDRLAAFwdqamR-LRDLLKFEFFF 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 528 LPGNTLK------------DFEEgcyllckSEAIQVTTKDILVTEKGntvleFLVG--LFKPFVESYQIICKYLLSEEED 593
Cdd:PRK03355 627 ADSDAFRanlraemawidpDWED-------RLAAGGDEIDALLRAKR-----PLMAhaMLRPFFEAYEVVADVLRDAPPD 694
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 7657134 594 HFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSSDVQKNALAACVRLGVVE 642
Cdd:PRK03355 695 TIDEKELTALALGLGRQYVLQGRVRSSESVSTLLFATARQLARDQGLLE 743
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
138-283 |
1.16e-30 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 116.61 E-value: 1.16e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 138 CVNEEGIQKLQRaiqEHPVVLLPSHRSYIDFLMLSFLLYNYDLPvPVIAAGMDFLGMKMVGELLRMSGAFFMRRtfgGNK 217
Cdd:pfam01553 1 RIEVHGLENLPR---GGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7657134 218 LYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISIS 283
Cdd:pfam01553 74 KDAAGTLEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
134-340 |
2.95e-26 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 106.34 E-value: 2.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 134 FSKVCVNEEGIQKLQRAIQEH-----PVVLLPSHRSYIDFLMLSFLLYNYdLPVPVIAAGMDFLGMKmvGELLRMSGAFF 208
Cdd:cd06551 1 FRYLLLNFFGFVRLEVKGPPPppgggPVLFVSNHSSWWDGLILFLLLERG-LRRDVYGLMDEELLER--YPFFTRLGAFS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 209 MRRTFGGnklYWAVFSEYVKTMLRNGYAPVEFFLEGTRSR-SAKTLTPKFGLLNIvmepffkREVFDTYLVPISISYDKI 287
Cdd:cd06551 78 VDRDSPR---SAAKSLKYVARLLSKPGSVVWIFPEGTRTRrDKRPLQFKPGVAHL-------AEKAGVPIVPVALRYTFE 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 7657134 288 LEetlyvyellgvpkpkesttgllkarkilsENFGSIHVYFGDPVSLRSLAAG 340
Cdd:cd06551 148 LF-----------------------------EQFPEIFVRIGPPIPYAETALG 171
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
156-285 |
1.26e-22 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 93.57 E-value: 1.26e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 156 VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLgMKMVGELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRNGY 235
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 7657134 236 aPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPffkrevfDTYLVPISISYD 285
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
85-602 |
2.52e-20 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 95.40 E-value: 2.52e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 85 IKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIR-FCAFtlSKVFKQIFSkVCVNEEGIQKLQRAIQEHPVVLLPSHR 163
Cdd:PRK11915 48 LRALADELGRDPDSVRAEAAGYLREMAASLDERAVQaWRGF--SRWLMRAYD-VLVDEDQITQLRKLDRKATLAFAFSHR 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 164 SYID-FLMLSFLLYNYDLPVPVIA-AGMDFLGMkmvGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNgYAPVEFF 241
Cdd:PRK11915 125 SYLDgMLLPEVILANRLSPALTFGgANLNFFPM---GAWAKRTGAIFIRRQTKDIPVYRFVLRAYAAQLVQN-HVNLTWS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 242 LEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSENF 321
Cdd:PRK11915 201 IEGGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEVEAMTTEAYGAVKRPEDLRFLVRLARQQGERL 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 322 GSIHVYFGDPVSLRS-LAAGRMSRSSynlvpryipqKQSEdmhafVTEVAYKMELLQIENMVLSPWTLIVAVLLQNRPSM 400
Cdd:PRK11915 281 GRAYLDFGEPLPLRKrLQELRADKSG----------TGSE-----IERIALDVEHRINRATPVTPTAVVSLALLGADRSL 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 401 DFDALVEKTLWLKGLTQAFGgfliWPDNKPAEEVVPASI--LLHSNIASlvkdQVILKVDSGdSEVVDGLML-QHitlLM 477
Cdd:PRK11915 346 SISEVLATVRPLASYIAARN----WAVAGAADLTNRSTIrwTLHQMVAS----GVVSVYDAG-TEAVWGIGEdQH---LV 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 478 CSAYRNQLLNIFVRPSLVAVALQMTPGFRKE------DVYSCFRFLRDVFADEFIFlPGNTL--KDFEEGCYLLCKSEAI 549
Cdd:PRK11915 414 AAFYRNTAIHILVDRAIAELALLAAAETTTNgsvspaTVRDEALSLRELLKFEFLF-SGRAQfeKDLANEVRLIGSVVDT 492
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 7657134 550 Q--VTTKDIL-VTEKGNTVLEFLVglFKPFVESYQIICKYLLSEEEDHFSEEQYLA 602
Cdd:PRK11915 493 SkaAAAADVWrLLESADLLLAHLV--LRPFLDAYHIVADRLAAHEDDSFDEEGFLA 546
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
293-582 |
4.72e-17 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 83.34 E-value: 4.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 293 YVYELLGVPKPKESTTGLLK-ARKILSENFGSIHVYFGDPVSLRSLAAGRMSRSSYnlvpryipqkQSEDMHAFVTEVAY 371
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLREFLDEQGDRPAT----------DAARRRLALQKLAF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 372 KMeLLQI-ENMVLSPWTLIVAVLLQNRP-SMDFDALVEKTLWL------KGLTQAFGGFLiwpdnkPAEEVVPASillhs 443
Cdd:pfam19277 71 EV-LSRInRVTPVMPTALVGTVLLTLRGrALTLSELIRRVEWLldyiraRGGPVAHFGDL------RTEEVVDRA----- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 444 nIASLVKDQVILKVDSGDSEV-----VDGLMLqhitllmcSAYRNQLLNIFVRPSLVAVALQMTP-----GFRKEDVYSC 513
Cdd:pfam19277 139 -LDVLGNAGLVTRVDGGPEPVyyiapEDHFQA--------SFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALWDQ 209
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 514 FRFLRDVFADEFIFLPGNTLK-DFEEGCYLLCKSEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQI 582
Cdd:pfam19277 210 VLRLRDLLKFEFFFPPKEGFReNLRAELDLLDPWEDRVITGERDIERLLGRENPDFACFLLWPFIEAYWL 279
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
152-338 |
3.06e-10 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 60.41 E-value: 3.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 152 QEHPVVLLPSHRSYIDFLMLSFLlynydLPVPV-IAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLywAVFsEYVKTM 230
Cdd:COG0204 41 ADGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 231 LRNGYAPVeFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISISYdkileeTLYVYELLGVPKPkesttgl 310
Cdd:COG0204 113 LKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE-------AGVPIVPVAIDG------TERALPKGFLPRP------- 171
|
170 180
....*....|....*....|....*...
gi 7657134 311 lkarkilsenfGSIHVYFGDPVSLRSLA 338
Cdd:COG0204 172 -----------GKVTVRIGPPIDPSDLE 188
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
155-344 |
4.30e-10 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 59.59 E-value: 4.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 155 PVVLLPSHRSYIDFLMLSFLLYNYdlPVPVIAAgmDFLGMKMVGELLRMSGAFFMRRtfGGNKLYWAVFsEYVKTMLRNG 234
Cdd:cd07989 25 PVIIVANHQSYLDPLVLGAALPRP--IRFVAKK--ELFKIPFLGWLLRLLGAIPIDR--GNGRSAREAL-REAIEALKEG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657134 235 YAPVeFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISISYdkileeTLYVYELLGVPKPkesttgllkar 314
Cdd:cd07989 98 ESVV-IFPEGTRSRDGELLPFKSGAFRLAKE-------AGVPIVPVAISG------TWGSLPKGKKLPR----------- 152
|
170 180 190
....*....|....*....|....*....|
gi 7657134 315 kilsenFGSIHVYFGDPVSLRSLAAGRMSR 344
Cdd:cd07989 153 ------PGRVTVRIGEPIPPEGLELAEEDR 176
|
|
| |
