3SGJ: Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgIII and antibodies lacking core fucose

PDB ID: 3SGJDownload
MMDB ID: 92385
PDB Deposition Date: 2011/6/15
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 3SGJ: trimeric; determined by author and by software (PISA)
Molecular Components in 3SGJ
Label Count Molecule
Proteins (3 molecules)
2
Human FC Fragment
(Gene symbol: IGHG1)
Molecule annotation
1
Human Fcg3a Receptor
(Gene symbol: FCGR3A)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
12
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
beta-D-mannopyranosebeta-D-mannopyranose
3
6
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
alpha-L-fucopyranosealpha-L-fucopyranose
5
1
MALONATE IONMALONATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303