6HLE: X-ray structure of furin in complex with the P6-P2-cyclized peptide H-Lys-Arg-Arg-Tle-Lys-4-Amba

PDB ID: 6HLEDownload
MMDB ID: 172093
PDB Deposition Date: 2018/9/11
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.994  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6HLE: dimeric; determined by author and by software (PISA)
Molecular Components in 6HLE
Label Count Molecule
Proteins (2 molecules)
1
Furin
Molecule annotation
1
Lys-arg-arg-tbg-lys-00s
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
3
CALCIUM IONCALCIUM ION
2
3
SODIUM IONSODIUM ION
3
1
CHLORIDE IONCHLORIDE ION
4
2
PHOSPHATE IONPHOSPHATE ION
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
1
3-[4-(3-oxidanylidenepropyl)piperazin-1-yl]propanal3-[4-(3-oxidanylidenepropyl)piperazin-1-yl]propanal
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303