6R6I: Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue

PDB ID: 6R6IDownload
MMDB ID: 179396
PDB Deposition Date: 2019/3/27
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 1.467  Å
Source Organism:
Similar Structures:
Biological Unit for 6R6I: tetrameric; determined by author
Molecular Components in 6R6I
Label Count Molecule
Proteins (4 molecules)
4
Transthyretin
(Gene symbol: TTR)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid
2
4
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303