6V6K: EGFR(T790M/V948R) in complex with LN2057

PDB ID: 6V6KDownload
MMDB ID: 186810
PDB Deposition Date: 2019/12/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6V6K: dimeric; determined by author and by software (PISA)
Molecular Components in 6V6K
Label Count Molecule
Proteins (2 molecules)
2
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
N-[3-({4-[4-(4-fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]pyridin-2-yl}amino)-4-methoxyphenyl]propanamideN-[3-({4-[4-(4-fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]pyridin-2-yl}amino)-4-methoxyphenyl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303