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Items: 1 to 20 of 1558

1.

Impact of pehR transcriptional regulator on Ralstonia solanacearum F1C1 gene expression patterns

(Submitter supplied) Ralstonia solanacearum, recognized as a pervasive plant pathogen causing lethal wilt disease in over 450 plant species worldwide, represents a substantial threat to economically vital crops including tomato, chili, and eggplant. Within R. solanacearum, pehR serves as a transcriptional regulator, forming part of the pehSR two-component regulatory system. This system governs the production of polygalacturonase (PG), a crucial extracellular enzyme involved in plant cell wall degradation and bacterial wilt development. more...
Organism:
Ralstonia solanacearum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29295
2 Samples
Download data: TXT
Series
Accession:
GSE269108
ID:
200269108
2.

Holliday junction resolvase RuvC targets biofilm eDNA to facilitate pathogen spread in plants

(Submitter supplied) Biofilm lifestyle is critical for bacterial pathogens to colonize and protect themselves from host immunity and antimicrobial chemicals in plants and animals. The formation and regulation mechanism of phytobacterial biofilm are still obscure. Here, we found that Ralstonia solanacearum Resistance to ultraviolet C (RuvC) is highly abundant in biofilm and positively regulates pathogenicity by governing systemic movement in tomato xylem. more...
Organism:
Ralstonia solanacearum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34644
6 Samples
Download data: TXT
Series
Accession:
GSE270737
ID:
200270737
3.

In vitro and transcriptomic variation in Neisseria musculi morphotypes correlate with colonization variability and persistence in vivo

(Submitter supplied) Asymptomatic colonization of the upper respiratory tract is a common trait of the two exclusive human pathogens, Neisseria gonorrhoeae and Neisseria meningitidis. In vivo models of pathogenic neisserial infections are heterologous systems that permit short-term persistence but do not fully recapitulate infections in humans. Studying Neisseria musculi (Nmus), an oral commensal, in laboratory mice allows investigation of Neisseria-host interactions that avoids host restriction barriers. more...
Organism:
Neisseria musculi
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30638
6 Samples
Download data: XLSX
Series
Accession:
GSE184230
ID:
200184230
4.

Genomic and transcriptomic analyses reveal insights into cadmium resistance mechanisms of Cupriavidus nantongensis E324

(Submitter supplied) The cadmium-resistant Cupriavidus sp. E324 strain has been previously shown to have a high potential for use in cadmium (Cd) remediation, due to its high capacity for cadmium bioaccumulation. According to the comparative genomic analysis, the E324 strain was most closely related to C. nantongensis X1 T , indicating that the E324 strain should be re-identified as C. nantongensis. To unravel the Cd tolerance mechanisms of C. more...
Organism:
Cupriavidus nantongensis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34734
6 Samples
Download data: TXT
Series
Accession:
GSE272856
ID:
200272856
5.

RNA-seq analyses of pathogenic Burkholderia glumae under in vivo rice panicle condition

(Submitter supplied) RNA-seq based transcriptome analysis was employed to understand the genome-wide expression patterns of B. glumae BGR1 under infected rice panicle tissue.
Organism:
Burkholderia glumae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL27527
3 Samples
Download data: TXT
Series
Accession:
GSE137969
ID:
200137969
6.

Transcriptional analysis of transposon mutants disrupted in glutathione or ergothioneine biosynthesis in Burkholderia thailandensis

(Submitter supplied) In this study we compare logarithmically grown Burkholderia thailadensis wildtype to a transposon mutant that is disrupted in gshA1, or gshA2, which are involved in glutathione biosynthesis or egtB, involved in ergothioneine biosynthesis using RNASeq to identify novel pathways where glutathione or ergothioneine may be involved.
Organism:
Burkholderia thailandensis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33677
8 Samples
Download data: CSV, XLSX
Series
Accession:
GSE240826
ID:
200240826
7.

RNA-seq based transcriptome analysis of plant pathogens under salt stress condition

(Submitter supplied) Plant pathogens require lethal virulence factors, susceptible hosts, and optimal environmental conditions for disease establishment. High soil salinity, exacerbated by climate change, significantly impacts agro-biological ecosystems. However, the overall interactions between plant pathogens and salt stress are not fully characterized or understood. This study examines the effects of salt stress on representative plant pathogens: Burkholderia gladioli, Pectobacterium carotovorum subsp. more...
Organism:
Ralstonia solanacearum; Pectobacterium carotovorum subsp. carotovorum; Burkholderia gladioli
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL29295 GPL34740 GPL34741
18 Samples
Download data: TXT
Series
Accession:
GSE272984
ID:
200272984
8.

TetR-like regulator BP1026B_II1561 controls aromatic amino acid biosynthesis and intracellular pathogenesis in Burkholderia pseudomallei [RNA-seq]

(Submitter supplied) We identified BP1026b_II1561 to be an important transcriptional regulator controling late stages of intracellular infection. RNA-seq analysis was performed to further investigate the regulatory network of II1561 regulation. ChIP-seq was also performed under the same conditions.
Organism:
Burkholderia pseudomallei
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32930
2 Samples
Download data: XLSX
Series
Accession:
GSE273460
ID:
200273460
9.

TetR-like regulator BP1026B_II1561 controls aromatic amino acid biosynthesis and intracellular pathogenesis in Burkholderia pseudomallei [ChIP-seq]

(Submitter supplied) We identified BP1026b_II1561 to be an important transcriptional regulator controling late stages of intracellular infection. RNA-seq analysis was performed to further investigate the regulatory network of II1561 regulation. ChIP-seq was also performed under the same conditions.
Organism:
Burkholderia pseudomallei
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL32930
2 Samples
Download data: XLSX
Series
Accession:
GSE273459
ID:
200273459
10.

Effect of oxygen and carbon dioxide on gene expression in Bordetella bronchiseptica strain RB50

(Submitter supplied) The classical bordetellae (Bordetella pertussis, B. parapertussis, and B. bronchiseptica) are obligate aerobes that use only oxygen as their terminal electron acceptor for electron transport-coupled oxidative phosphorylation. Therefore, access to oxygen is critical for these bacteria to survive. To better understand how B. bronchiseptica changes its gene regulation when faced with different levels of oxygen, we grew liquid cultures of B. more...
Organism:
Bordetella bronchiseptica
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34533
12 Samples
Download data: TSV
Series
Accession:
GSE268598
ID:
200268598
11.

RNA-seq analysis in simulated microgravity unveils down-regulation of the beta-rhizobial siderophore phymabactin

(Submitter supplied) Exploiting the symbiotic interaction between crops and nitrogen-fixing bacteria is a simple and ecological solution to promote plants growth in prospective extraterrestrial human outposts. In this study, we investigated the adaptation of the legume symbiont Paraburkholderia phymatum to simulated microgravity (s0-g) at the transcriptome level by performing an RNA-Seq analysis. The results revealed a drastic effect on gene expression, with roughly 23 % of P. more...
Organism:
Paraburkholderia phymatum STM815
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22728
6 Samples
Download data: TXT
Series
Accession:
GSE255155
ID:
200255155
12.

Pathogenesis of Achromobacter xylosoxidans respiratory infections: colonization and persistence in vivo and differential gene expression in cystic fibrosis sputum

(Submitter supplied) The goals of this study were to determine differential gene expression between Achromobacter xylosoxidans clinical isolate Ax 7 in a synthetic artificial sputum media compared to a rich media control (LB).
Organism:
Achromobacter xylosoxidans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33525
6 Samples
Download data: CSV, TXT
Series
Accession:
GSE235679
ID:
200235679
13.

Gene expression profiling of Ralstonia solanacearum in unexplored environmental niches reveals essential genes to complete its life cycle

(Submitter supplied) Bacterial pathogens exhibit a remarkable ability to persist and thrive in diverse ecological niches. Understanding the mechanisms enabling their transition between environments is crucial to control dissemination and potential disease outbreaks. Here, we use Ralstonia solanacearum, the causing agent of the bacterial wilt disease, as a model to investigate the bacterial transcriptomic adaptation to two environments, water and soil, and compare it with the well-studied in planta gene expression. more...
Organism:
Ralstonia solanacearum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33632
6 Samples
Download data: CSV, XLSX
Series
Accession:
GSE239723
ID:
200239723
14.

Black Carbon Impacts on Paraburkholderia xenovorans Strain LB400 Cell Enrichment and Activity: Implications toward Lower-Chlorinated Polychlorinated Biphenyls Biodegradation

(Submitter supplied) Volatilization of lower-chlorinated polychlorinated biphenyls (LC-PCBs) from sediment poses health threats to nearby communities and ecosystems. Biodegradation combined with black carbon (BC) materials is an emerging approach to remove PCBs from sediment, but development of aerobic biofilms on BC for long-term, sustained LC-PCBs remediation is poorly understood. This work aimed to characterize cell enrichment and activity of biphenyl- and benzoate-grown Paraburkholderia xenovorans strain LB400 on various BCs. more...
Organism:
Paraburkholderia xenovorans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33884
12 Samples
Download data: XLSX
Series
Accession:
GSE246487
ID:
200246487
15.

Effects of metals on the gene expression of Cupriavidus basilensis SRS

(Submitter supplied) To investigate the molecular mechanisms of how Cupriavidus basilensis SRS may aid bioextraction of metals from ores, we exposed C. basilensis SRS to different metals, as well as natural ores
Organism:
Cupriavidus basilensis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32789
10 Samples
Download data: TXT
Series
Accession:
GSE216827
ID:
200216827
16.

Longitudinal multi-omics analysis of Bordetella pertussis Tohama I fermentation

(Submitter supplied) A longitudinal multi-omics analysis was carried out over a 26-hour small-scale fermentation of B. pertussis. Fermentations were performed in batch mode and under culture conditions intended to mimic industrial processes.
Organism:
Bordetella pertussis Tohama I
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32624
21 Samples
Download data: XLSX
Series
Accession:
GSE212531
ID:
200212531
17.

Transcriptome profiling of Burkholderia pseudomallei wildtype strain1026b and BP1026b_II1046::T4 insertion mutant

(Submitter supplied) We identified BP1026b_II1046 (SapR) to be an important transcriptional regulator controling surface attachment factor 1 (sap1). RNA-seq analysis was performed to further investigate the regulatory network of SapR regulation.
Organism:
Burkholderia pseudomallei
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32930
6 Samples
Download data: XLSX
Series
Accession:
GSE220579
ID:
200220579
18.

Transcriptional responses of Neisseria gonorrhoeae to glucose and lactate: implications for resistance to oxidative damage and biofilm formation

(Submitter supplied) Carbon catabolite repression (CCR) is a gene regulation process that allows bacteria to use carbon-energy sources in a hierarchical manner. Thus, the presence of a preferred sugar, usually D-glucose, results in downregulation of genes participating in the transport and catabolic pathways of secondary carbon sources. Further, CCR controls the expression of global regulators that control expression of many genes involved in multiple aspects of bacterial physiology such as stress response proteins and virulence factors. more...
Organism:
Neisseria gonorrhoeae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22011
8 Samples
Download data: XLSX
Series
Accession:
GSE148774
ID:
200148774
19.

RNA-seq of suspension-grown vs. adherent Neisseria gonorrhoeae under conditions of zinc sequestration or zinc excess

(Submitter supplied) Deep sequencing of cDNA of Neisseria gonorrhoeae bacteria that were grown in suspension or adherent to acid-washed glass coverslips, in media where zinc was sequestered or available in excess.
Organism:
Neisseria gonorrhoeae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28673
18 Samples
Download data: RESULTS
Series
Accession:
GSE191020
ID:
200191020
20.

Genome wide identification of BysR binding sites in Burkholderia sp. JP2-270

(Submitter supplied) To verify genes that are directly regulated by BysR, we used DNA affinity purification sequencing analysis (DAP-seq) for genome-wide recognition of BysR binding sites in vitro. The HALO-fusion BysR protein was successfully expressed and purified. After affinity purification and sequencing, at least 22 million double-end reads per sample were generated and with > 99 % of reads uniquely mapped to the JP2-270 genome. more...
Organism:
Burkholderia sp. JP2-270
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL31243
3 Samples
Download data: FA, TXT, WIG
Series
Accession:
GSE193916
ID:
200193916
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