U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127830358 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78110270-78110904 [ Homo sapiens (human) ]

Gene ID: 127830358, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Gene symbol
LOC127830358
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78110270-78110904
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LOC127830358 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (77817928..77818562)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (75680144..75680778)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (78110270..78110904)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene leucine rich repeat and Ig domain containing 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:77937918-77938418 Neighboring gene LINGO1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:77942484-77942984 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:77952267-77953188 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:77959162-77959662 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:77959663-77960163 Neighboring gene LINGO1 antisense RNA 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:77963681-77964597 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:77969616-77970141 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78004126-78004664 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:78005958-78006458 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78029912-78030425 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78031453-78031964 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78031965-78032478 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78032479-78032990 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78033504-78034015 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr15:78039893-78040461 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78040462-78041029 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr15:78041067-78041828 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:78044539-78044736 Neighboring gene MPRA-validated peak2394 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78076600-78077183 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78077259-78077760 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78090197-78090896 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78092471-78092970 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78096516-78097110 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78100953-78101820 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78103235-78103736 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:78110905-78111539 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9899 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78156801-78157306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78157307-78157812 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78161208-78161708 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78163573-78164411 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78171267-78171767 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78180036-78180778 Neighboring gene chondroitin sulfate proteoglycan 4 pseudogene 13 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78196402-78196966 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:78196967-78197531 Neighboring gene dynamin 1 pseudogene 9

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_131840.1 

    Range
    101..735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    77817928..77818562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    75680144..75680778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases