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    Rab27 RAS oncogene family member Rab27 [ Ixodes scapularis (black-legged tick) ]

    Gene ID: 8033539, updated on 31-Jul-2024

    Summary

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    Gene symbol
    Rab27
    Gene description
    RAS oncogene family member Rab27
    See related
    VectorBase:ISCP_023343; EnsemblRapid:LOC8033539
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ixodes scapularis
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes
    Orthologs
    fruit fly all
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    Genomic context

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    See Rab27 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current ASM1692078v2 (GCF_016920785.2) Unplaced Scaffold NW_024609835.1 (127423298..127620343, complement)
    102 previous assembly Ixodes_scapularus_ComboLowHiFi (GCF_016920785.1) Unplaced Scaffold NW_024388004.1 (111674..237198, complement)

    NW_024609835.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain-containing protein 6 Neighboring gene uncharacterized LOC121833224 Neighboring gene uncharacterized LOC121837368 Neighboring gene uncharacterized LOC120850551 Neighboring gene Glycerol-3-phosphate dehydrogenase 1 Neighboring gene Apoptosis inducing factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of Rab27 in tick extracellular vesicle biogenesis and pathogen infection. Butler LR, et al. Parasit Vectors, 2024 Feb 9. PMID 38336752, Free PMC Article
    2. Transcriptome of the female synganglion of the black-legged tick Ixodes scapularis (Acari: Ixodidae) with comparison between Illumina and 454 systems. Egekwu N, et al. PLoS One, 2014. PMID 25075967, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The role of Rab27 in tick extracellular vesicle biogenesis and pathogen infection.
      Title: The role of Rab27 in tick extracellular vesicle biogenesis and pathogen infection.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in melanosome transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in melanosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in secretory granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras-related protein Rab-27A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ixodes scapularis Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1692078v2

    Genomic

    1. NW_024609835.1 Reference ASM1692078v2

      Range
      127423298..127620343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042289797.1 → XP_042145731.1  ras-related protein Rab-27A

      Related
      XP_042145731.1, XM_042289797.1
      Conserved Domains (1) summary
      cl38936
      Location:18 → 194
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_040211328.2 → XP_040067262.1  ras-related protein Rab-27A

      Related
      XP_040067262.1, XM_040211328.2
      Conserved Domains (1) summary
      cl38936
      Location:18 → 194
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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