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    trmt2a.S tRNA methyltransferase 2 homolog A S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100101284, updated on 4-Jan-2025

    Summary

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    Official Symbol
    trmt2a.S
    Official Full Name
    tRNA methyltransferase 2 homolog A S homeolog
    Primary source
    Xenbase:XB-GENE-980824
    Locus tag
    XELAEV_18010554mg
    See related
    EnsemblRapid:ENSXLAG00005007985 AllianceGenome:Xenbase:XB-GENE-980824
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    htf9c; trmt2a
    Summary
    Predicted to enable RNA binding activity; RNA methyltransferase activity; and S-adenosylmethionine-dependent methyltransferase activity. Predicted to act upstream of or within RNA modification; RNA processing; and methylation. Orthologous to human TRMT2A (tRNA methyltransferase 2 homolog A). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See trmt2a.S in Genome Data Viewer
    Location:
    chromosome: 1S
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (144114160..144126021, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (128361633..128373687, complement)

    Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene catechol-O-methyltransferase S homeolog Neighboring gene ARVCF, delta catenin family member S homeolog Neighboring gene small nucleolar RNA SNORA77 Neighboring gene uncharacterized LOC121399488 Neighboring gene RAN binding protein 1 S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA methyltransferase 2 homolog A S homeolog
    Names
    TRM2 tRNA methyltransferase 2 homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099875.1 → NP_001093345.2  tRNA methyltransferase 2 homolog A S homeolog

      Status: PROVISIONAL

      Source sequence(s)
      BC142550
      UniProtKB/TrEMBL
      A0A1L8HQG2, A0A974DUR2, A5PKN1
      Related
      ENSXLAP00005022922.1, ENSXLAT00005023624.1
      Conserved Domains (4) summary
      COG0724
      Location:67 → 165
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      COG2265
      Location:189 → 594
      TrmA; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]
      cd12439
      Location:65 → 143
      RRM_TRMT2A; RNA recognition motif in tRNA (uracil-5-)-methyltransferase homolog A (TRMT2A) and similar proteins
      cl17173
      Location:391 → 601
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      144114160..144126021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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