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Brain glioblastoma

MedGen UID:
138100
•Concept ID:
C0349543
•
Neoplastic Process
Synonyms: Brain Glioblastoma; brain glioblastoma; brain glioblastoma (disease); brain glioblastoma multiforme; brain glioblastoma multiforme (disease); glioblastoma (disease) of brain; Glioblastoma multiforme of brain; glioblastoma multiforme of brain; glioblastoma multiforme of the brain; grade IV astrocytic neoplasm of brain; grade IV astrocytic neoplasm of the brain; grade IV astrocytic tumor of brain; grade IV astrocytic tumor of the brain; grade IV astrocytic tumour of brain; grade IV astrocytic tumour of the brain; grade IV brain astrocytic neoplasm; grade IV brain astrocytic tumor; grade IV brain astrocytic tumour
SNOMED CT: Glioblastoma multiforme of brain (276828006)
 
Monarch Initiative: MONDO:0002501

Definition

A glioblastoma that arises from the brain, usually the cerebral hemispheres. [from NCI]

Professional guidelines

PubMed

Live-Cell Synchrotron-Based FTIR Evaluation of Metabolic Compounds in Brain Glioblastoma Cell Lines after Riluzole Treatment.
Dučić T, Ninkovic M, Martínez-Rovira I, Sperling S, Rohde V, Dimitrijević D, Jover Mañas GV, Vaccari L, Birarda G, Yousef I
Anal Chem 2022 Feb 1;94(4):1932-1940. Epub 2021 Dec 29 doi: 10.1021/acs.analchem.1c02076. PMID: 34965097
Prospect of rindopepimut in the treatment of glioblastoma.
Elsamadicy AA, Chongsathidkiet P, Desai R, Woroniecka K, Farber SH, Fecci PE, Sampson JH
Expert Opin Biol Ther 2017 Apr;17(4):507-513. Epub 2017 Mar 5 doi: 10.1080/14712598.2017.1299705. PMID: 28274144Free PMC Article
Out of Warburg effect: An effective cancer treatment targeting the tumor specific metabolism and dysregulated pH.
Schwartz L, Seyfried T, Alfarouk KO, Da Veiga Moreira J, Fais S
Semin Cancer Biol 2017 Apr;43:134-138. Epub 2017 Jan 22 doi: 10.1016/j.semcancer.2017.01.005. PMID: 28122260

Recent clinical studies

Etiology

An exploration of causal relationships between nine neurological diseases and the risk of breast cancer: a Mendelian randomization study.
Ren F, Yang C, Feng K, Shang Q, Liu J, Kang X, Wang X, Wang X
Aging (Albany NY) 2024 Apr 24;16(8):7101-7118. doi: 10.18632/aging.205745. PMID: 38663930Free PMC Article
Extracranial metastasis of brain glioblastoma outside CNS: Pathogenesis revisited.
Kurdi M, Baeesa S, Okal F, Bamaga AK, Faizo E, Fathaddin AA, Alkhotani A, Karami MM, Bahakeem B
Cancer Rep (Hoboken) 2023 Dec;6(12):e1905. Epub 2023 Oct 9 doi: 10.1002/cnr2.1905. PMID: 37814403Free PMC Article
Prospect of rindopepimut in the treatment of glioblastoma.
Elsamadicy AA, Chongsathidkiet P, Desai R, Woroniecka K, Farber SH, Fecci PE, Sampson JH
Expert Opin Biol Ther 2017 Apr;17(4):507-513. Epub 2017 Mar 5 doi: 10.1080/14712598.2017.1299705. PMID: 28274144Free PMC Article
Brain cancer stem cells.
Piccirillo SG, Binda E, Fiocco R, Vescovi AL, Shah K
J Mol Med (Berl) 2009 Nov;87(11):1087-95. Epub 2009 Sep 29 doi: 10.1007/s00109-009-0535-3. PMID: 19784875
Biotherapy with the pineal immunomodulating hormone melatonin versus melatonin plus aloe vera in untreatable advanced solid neoplasms.
Lissoni P, Giani L, Zerbini S, Trabattoni P, Rovelli F
Nat Immun 1998;16(1):27-33. doi: 10.1159/000069427. PMID: 9789122

Diagnosis

An exploration of causal relationships between nine neurological diseases and the risk of breast cancer: a Mendelian randomization study.
Ren F, Yang C, Feng K, Shang Q, Liu J, Kang X, Wang X, Wang X
Aging (Albany NY) 2024 Apr 24;16(8):7101-7118. doi: 10.18632/aging.205745. PMID: 38663930Free PMC Article
Segmenting brain glioblastoma using dense-attentive 3D DAF(2).
Domadia SG, Thakkar FN, Ardeshana MA
Phys Med 2024 Mar;119:103304. Epub 2024 Feb 10 doi: 10.1016/j.ejmp.2024.103304. PMID: 38340694
Wasserstein HOG: Local Directionality Extraction via Optimal Transport.
Zhu J, Veeraraghavan H, Jiang J, Oh JH, Norton L, Deasy JO, Tannenbaum A
IEEE Trans Med Imaging 2024 Mar;43(3):916-927. Epub 2024 Mar 5 doi: 10.1109/TMI.2023.3325295. PMID: 37874704Free PMC Article
Extracranial metastasis of brain glioblastoma outside CNS: Pathogenesis revisited.
Kurdi M, Baeesa S, Okal F, Bamaga AK, Faizo E, Fathaddin AA, Alkhotani A, Karami MM, Bahakeem B
Cancer Rep (Hoboken) 2023 Dec;6(12):e1905. Epub 2023 Oct 9 doi: 10.1002/cnr2.1905. PMID: 37814403Free PMC Article
Prospect of rindopepimut in the treatment of glioblastoma.
Elsamadicy AA, Chongsathidkiet P, Desai R, Woroniecka K, Farber SH, Fecci PE, Sampson JH
Expert Opin Biol Ther 2017 Apr;17(4):507-513. Epub 2017 Mar 5 doi: 10.1080/14712598.2017.1299705. PMID: 28274144Free PMC Article

Therapy

Biopolymer immune implants co-loaded with TMZ, R848 and IOX1 for perioperative therapy of glioblastoma.
Lv P, Wang Z, Si X, Su J, Yu Z, Yu H, Ji G, Song W
Acta Biomater 2024 Nov;189:143-154. Epub 2024 Oct 4 doi: 10.1016/j.actbio.2024.09.053. PMID: 39368721
Fiber Optic-Mediated Type I Photodynamic Therapy of Brain Glioblastoma Based on an Aggregation-Induced Emission Photosensitizer.
Zhang W, Kang M, Li X, Pan Y, Li Z, Zhang Y, Liao C, Xu G, Zhang Z, Tang BZ, Xu Z, Wang D
Adv Mater 2024 Nov;36(47):e2410142. Epub 2024 Sep 30 doi: 10.1002/adma.202410142. PMID: 39344926
An exploration of causal relationships between nine neurological diseases and the risk of breast cancer: a Mendelian randomization study.
Ren F, Yang C, Feng K, Shang Q, Liu J, Kang X, Wang X, Wang X
Aging (Albany NY) 2024 Apr 24;16(8):7101-7118. doi: 10.18632/aging.205745. PMID: 38663930Free PMC Article
Prospect of rindopepimut in the treatment of glioblastoma.
Elsamadicy AA, Chongsathidkiet P, Desai R, Woroniecka K, Farber SH, Fecci PE, Sampson JH
Expert Opin Biol Ther 2017 Apr;17(4):507-513. Epub 2017 Mar 5 doi: 10.1080/14712598.2017.1299705. PMID: 28274144Free PMC Article
Delivering siRNA and Chemotherapeutic Molecules Across BBB and BTB for Intracranial Glioblastoma Therapy.
Yang ZZ, Gao W, Liu YJ, Pang N, Qi XR
Mol Pharm 2017 Apr 3;14(4):1012-1022. Epub 2017 Mar 2 doi: 10.1021/acs.molpharmaceut.6b00819. PMID: 28252970

Prognosis

An exploration of causal relationships between nine neurological diseases and the risk of breast cancer: a Mendelian randomization study.
Ren F, Yang C, Feng K, Shang Q, Liu J, Kang X, Wang X, Wang X
Aging (Albany NY) 2024 Apr 24;16(8):7101-7118. doi: 10.18632/aging.205745. PMID: 38663930Free PMC Article
Wasserstein HOG: Local Directionality Extraction via Optimal Transport.
Zhu J, Veeraraghavan H, Jiang J, Oh JH, Norton L, Deasy JO, Tannenbaum A
IEEE Trans Med Imaging 2024 Mar;43(3):916-927. Epub 2024 Mar 5 doi: 10.1109/TMI.2023.3325295. PMID: 37874704Free PMC Article
The effect of fitting the reference photon dose-response on the clonogenic survival predicted with the Mayo Clinic Florida microdosimetric kinetic model in case of accelerated ions.
Parisi A, Beltran CJ, Furutani KM
Radiat Prot Dosimetry 2023 Oct 11;199(15-16):1953-1957. doi: 10.1093/rpd/ncac235. PMID: 37819314
Extracranial metastasis of brain glioblastoma outside CNS: Pathogenesis revisited.
Kurdi M, Baeesa S, Okal F, Bamaga AK, Faizo E, Fathaddin AA, Alkhotani A, Karami MM, Bahakeem B
Cancer Rep (Hoboken) 2023 Dec;6(12):e1905. Epub 2023 Oct 9 doi: 10.1002/cnr2.1905. PMID: 37814403Free PMC Article
Natural history of spinal cord metastasis from brain glioblastomas.
Amelot A, Terrier LM, Cognacq G, Jecko V, Marlier B, Seizeur R, Emery E, Bauchet L, Roualdes V, Voirin J, Joubert C, Mandonnet E, Lemnos L, Mathon B, Le Reste PJ, Coca A, Petit A, Rigau V, Mokhtari K, Rousseau A, Metellus P, Figarella-Branger D, Gauchotte G, Farah K, Pallud J, Zemmoura I
J Neurooncol 2023 Apr;162(2):373-382. Epub 2023 Mar 29 doi: 10.1007/s11060-023-04298-3. PMID: 36991306

Clinical prediction guides

An exploration of causal relationships between nine neurological diseases and the risk of breast cancer: a Mendelian randomization study.
Ren F, Yang C, Feng K, Shang Q, Liu J, Kang X, Wang X, Wang X
Aging (Albany NY) 2024 Apr 24;16(8):7101-7118. doi: 10.18632/aging.205745. PMID: 38663930Free PMC Article
Segmenting brain glioblastoma using dense-attentive 3D DAF(2).
Domadia SG, Thakkar FN, Ardeshana MA
Phys Med 2024 Mar;119:103304. Epub 2024 Feb 10 doi: 10.1016/j.ejmp.2024.103304. PMID: 38340694
Wasserstein HOG: Local Directionality Extraction via Optimal Transport.
Zhu J, Veeraraghavan H, Jiang J, Oh JH, Norton L, Deasy JO, Tannenbaum A
IEEE Trans Med Imaging 2024 Mar;43(3):916-927. Epub 2024 Mar 5 doi: 10.1109/TMI.2023.3325295. PMID: 37874704Free PMC Article
The effect of fitting the reference photon dose-response on the clonogenic survival predicted with the Mayo Clinic Florida microdosimetric kinetic model in case of accelerated ions.
Parisi A, Beltran CJ, Furutani KM
Radiat Prot Dosimetry 2023 Oct 11;199(15-16):1953-1957. doi: 10.1093/rpd/ncac235. PMID: 37819314
In-Depth Matrisome and Glycoproteomic Analysis of Human Brain Glioblastoma Versus Control Tissue.
Sethi MK, Downs M, Shao C, Hackett WE, Phillips JJ, Zaia J
Mol Cell Proteomics 2022 Apr;21(4):100216. Epub 2022 Feb 23 doi: 10.1016/j.mcpro.2022.100216. PMID: 35202840Free PMC Article

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