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Bilateral Malignant Neoplasm

MedGen UID:: 146769
•Concept ID:: C0677861
•: Neoplastic Process

Synonym:

bilateral cancer

Definition

A malignant neoplasm that affects both sides of an organ in a simultaneous or non-simultaneous manner. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBilateral Malignant Neoplasm

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Malignant neoplastic disease
        Bilateral Malignant Neoplasm
        Bilateral Carcinoma
        Bilateral breast carcinoma
        Contralateral Breast Carcinoma
        Synchronous bilateral breast carcinoma
        Bilateral Synchronous Sporadic Renal Cell Carcinoma
        bilateral retinoblastoma

Professional guidelines

PubMed

European Society of Endocrinology clinical practice guidelines on the management of adrenal incidentalomas, in collaboration with the European Network for the Study of Adrenal Tumors.

Fassnacht M, Tsagarakis S, Terzolo M, Tabarin A, Sahdev A, Newell-Price J, Pelsma I, Marina L, Lorenz K, Bancos I, Arlt W, Dekkers OM
Eur J Endocrinol 2023 Jul 20;189(1):G1-G42. doi: 10.1093/ejendo/lvad066. PMID: 37318239

Diagnosis and treatment of primary aldosteronism.

Reincke M, Bancos I, Mulatero P, Scholl UI, Stowasser M, Williams TA
Lancet Diabetes Endocrinol 2021 Dec;9(12):876-892. doi: 10.1016/S2213-8587(21)00210-2. PMID: 34798068

Diagnosis and Management of Endometrial Cancer.

Braun MM, Overbeek-Wager EA, Grumbo RJ
Am Fam Physician 2016 Mar 15;93(6):468-74. PMID: 26977831

See all (1881)

Recent clinical studies

Etiology

Management of Central and Peripheral Nervous System Tumors in Patients with Neurofibromatosis.

Brown R
Curr Oncol Rep 2023 Dec;25(12):1409-1417. Epub 2023 Oct 31 doi: 10.1007/s11912-023-01451-z. PMID: 37906356

Phyllodes Tumor as a Secondary Neoplasm in Survivors of Childhood Cancer: A Tertiary Care Cancer Centre Experience.

Agrawal R, Sahay A, Patil A, Ramadwar M, Prasad M, Popat P, Joshi S, Shet T, Desai S
J Pediatr Hematol Oncol 2022 Jul 1;44(5):264-267. Epub 2022 Feb 4 doi: 10.1097/MPH.0000000000002415. PMID: 35129147

Impact of retroperitoneal lymph node dissection in ovarian cancer - time for paradigm shift?

Tato-Varela S, Kuhn W
Horm Mol Biol Clin Investig 2019 Aug 9;41(3) doi: 10.1515/hmbci-2019-0020. PMID: 31398143

Rosai-Dorfman disease with extranodal involvement.

Hashimoto K, Kariya S, Onoda T, Ooue T, Yamashita Y, Naka K, Okano M, Nishizaki K
Laryngoscope 2014 Mar;124(3):701-4. Epub 2013 Jul 29 doi: 10.1002/lary.24290. PMID: 23818241

Recommendations for women with lobular carcinoma in situ (LCIS).

Oppong BA, King TA
Oncology (Williston Park) 2011 Oct;25(11):1051-6, 1058. PMID: 22106556

See all (16667)

Diagnosis

Bilaterally Asymmetrical Becker's Nevus.

Zainab Z, Malik NA, Obaid S, Mumtaz M, Aftab K, Malik S, Pervaiz A, Syed Z
J Ayub Med Coll Abbottabad 2021 Apr-Jun;33(2):347-348. PMID: 34137561

Metastatic Bilateral Strumal Carcinoid: A Case Report and Review of the Literature.

Borghese M, Razzore P, Ferrero A, Daniele L, Mariani LL, Sgro LG, DE Rosa G, Biglia N
Anticancer Res 2019 Sep;39(9):5053-5056. doi: 10.21873/anticanres.13697. PMID: 31519614

Clinical Presentation, Natural History, and Prognosis of Diffuse Low-Grade Gliomas.

Smits A, Jakola AS
Neurosurg Clin N Am 2019 Jan;30(1):35-42. Epub 2018 Nov 1 doi: 10.1016/j.nec.2018.08.002. PMID: 30470403

A giant pelvic malignant schwannoma: a case report and literature review.

Xu H, Sha N, Li HW, Bai M, Chen X, Hu HL, Wu CL
Int J Clin Exp Pathol 2015;8(11):15363-8. Epub 2015 Nov 1 PMID: 26823895 Free PMC Article

Retinoblastoma.

Rodriguez-Galindo C, Orbach DB, VanderVeen D
Pediatr Clin North Am 2015 Feb;62(1):201-23. doi: 10.1016/j.pcl.2014.09.014. PMID: 25435120

See all (20470)

Therapy

Management of Central and Peripheral Nervous System Tumors in Patients with Neurofibromatosis.

Brown R
Curr Oncol Rep 2023 Dec;25(12):1409-1417. Epub 2023 Oct 31 doi: 10.1007/s11912-023-01451-z. PMID: 37906356

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer.

van den Heerik ASVM, Horeweg N, Nout RA, Lutgens LCHW, van der Steen-Banasik EM, Westerveld GH, van den Berg HA, Slot A, Koppe FLA, Kommoss S, Mens JWM, Nowee ME, Bijmolt S, Cibula D, Stam TC, Jurgenliemk-Schulz IM, Snyers A, Hamann M, Zwanenburg AG, Coen VLMA, Vandecasteele K, Gillham C, Chargari C, Verhoeven-Adema KW, Putter H, van den Hout WB, Wortman BG, Nijman HW, Bosse T, Creutzberg CL
Int J Gynecol Cancer 2020 Dec;30(12):2002-2007. Epub 2020 Oct 12 doi: 10.1136/ijgc-2020-001929. PMID: 33046573 Free PMC Article

Surgical Treatment of Neuroblastoma.

Ben Barak A, Golan H, Waldman D, Arkovitz MS
Isr Med Assoc J 2017 Nov;19(11):691-695. PMID: 29185283

Rosai-Dorfman disease with extranodal involvement.

Hashimoto K, Kariya S, Onoda T, Ooue T, Yamashita Y, Naka K, Okano M, Nishizaki K
Laryngoscope 2014 Mar;124(3):701-4. Epub 2013 Jul 29 doi: 10.1002/lary.24290. PMID: 23818241

Peritoneal mesothelioma.

Taub RN, Keohan ML, Chabot JC, Fountain KS, Plitsas M
Curr Treat Options Oncol 2000 Oct;1(4):303-12. doi: 10.1007/s11864-000-0046-5. PMID: 12057156

See all (9995)

Prognosis

Rosai-Dorfman disease with extranodal involvement.

Hashimoto K, Kariya S, Onoda T, Ooue T, Yamashita Y, Naka K, Okano M, Nishizaki K
Laryngoscope 2014 Mar;124(3):701-4. Epub 2013 Jul 29 doi: 10.1002/lary.24290. PMID: 23818241

Current assessment and management of glomus tumors.

Semaan MT, Megerian CA
Curr Opin Otolaryngol Head Neck Surg 2008 Oct;16(5):420-6. doi: 10.1097/MOO.0b013e32830c4595. PMID: 18797283

Peritoneal mesothelioma.

Taub RN, Keohan ML, Chabot JC, Fountain KS, Plitsas M
Curr Treat Options Oncol 2000 Oct;1(4):303-12. doi: 10.1007/s11864-000-0046-5. PMID: 12057156

Role of radiation therapy in the management of carcinoma in situ of the larynx.

Small W Jr, Mittal BB, Brand WN, Shetty RM, Rademaker AW, Beck GG, Hoover SV
Laryngoscope 1993 Jun;103(6):663-7. doi: 10.1288/00005537-199306000-00015. PMID: 8502100

Epithelial ovarian tumors of low malignant potential.

Massad LS Jr, Hunter VJ, Szpak CA, Clarke-Pearson DL, Creasman WT
Obstet Gynecol 1991 Dec;78(6):1027-32. PMID: 1945202

See all (12406)

Clinical prediction guides

Diagnostic challenges in cyclic Cushing's syndrome: a systematic review.

Nowak E, Vogel F, Albani A, Braun L, Rubinstein G, Zopp S, Ritzel K, Beuschlein F, Theodoropoulou M, Reincke M
Lancet Diabetes Endocrinol 2023 Aug;11(8):593-606. Epub 2023 Jul 7 doi: 10.1016/S2213-8587(23)00150-X. PMID: 37429301

Assessment of Sentinel Lymph Node Biopsy vs Lymphadenectomy for Intermediate- and High-Grade Endometrial Cancer Staging.

Cusimano MC, Vicus D, Pulman K, Maganti M, Bernardini MQ, Bouchard-Fortier G, Laframboise S, May T, Hogen LF, Covens AL, Gien LT, Kupets R, Rouzbahman M, Clarke BA, Mirkovic J, Cesari M, Turashvili G, Zia A, Ene GEV, Ferguson SE
JAMA Surg 2021 Feb 1;156(2):157-164. doi: 10.1001/jamasurg.2020.5060. PMID: 33175109 Free PMC Article

Secondary Arterial Hypertension: From Routine Clinical Practice to Evidence in Patients with Adrenal Tumor.

Grasso M, Boscaro M, Scaroni C, Ceccato F
High Blood Press Cardiovasc Prev 2018 Dec;25(4):345-354. Epub 2018 Nov 10 doi: 10.1007/s40292-018-0288-6. PMID: 30415425

Pulmonary epithelioid hemangioendothelioma.

Mizuno Y, Iwata H, Shirahashi K, Hirose Y, Takemura H
Gen Thorac Cardiovasc Surg 2011 Apr;59(4):297-300. Epub 2011 Apr 12 doi: 10.1007/s11748-010-0651-6. PMID: 21484560

Simple ultrasound-based rules for the diagnosis of ovarian cancer.

Timmerman D, Testa AC, Bourne T, Ameye L, Jurkovic D, Van Holsbeke C, Paladini D, Van Calster B, Vergote I, Van Huffel S, Valentin L
Ultrasound Obstet Gynecol 2008 Jun;31(6):681-90. doi: 10.1002/uog.5365. PMID: 18504770

See all (8688)

Recent systematic reviews

Salpingectomy for the Primary Prevention of Ovarian Cancer: A Systematic Review.

Kahn RM, Gordhandas S, Godwin K, Stone RL, Worley MJ Jr, Lu KH, Long Roche KC
JAMA Surg 2023 Nov 1;158(11):1204-1211. doi: 10.1001/jamasurg.2023.4164. PMID: 37672283 Free PMC Article

Diagnostic challenges in cyclic Cushing's syndrome: a systematic review.

Available evidence on HIFU for focal treatment of prostate cancer: a systematic review.

Bakavicius A, Marra G, Macek P, Robertson C, Abreu AL, George AK, Malavaud B, Coloby P, Rischmann P, Moschini M, Rastinehad AR, Sidana A, Stabile A, Tourinho-Barbosa R, de la Rosette J, Ahmed H, Polascik T, Cathelineau X, Sanchez-Salas R
Int Braz J Urol 2022 Mar-Apr;48(2):263-274. doi: 10.1590/S1677-5538.IBJU.2021.0091. PMID: 34003610 Free PMC Article

Outcomes of Minimally Invasive Thyroid Surgery - A Systematic Review and Meta-Analysis.

de Vries LH, Aykan D, Lodewijk L, Damen JAA, Borel Rinkes IHM, Vriens MR
Front Endocrinol (Lausanne) 2021;12:719397. Epub 2021 Aug 12 doi: 10.3389/fendo.2021.719397. PMID: 34456874 Free PMC Article

PROSPECT guidelines update for evidence-based pain management after prostatectomy for cancer.

Lemoine A, Witdouck A, Beloeil H, Bonnet F; PROSPECT Working Group Of The European Society Of Regional Anaesthesia And Pain Therapy (ESRA)
Anaesth Crit Care Pain Med 2021 Aug;40(4):100922. Epub 2021 Jun 29 doi: 10.1016/j.accpm.2021.100922. PMID: 34197976

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MedGen

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Bilateral Malignant Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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