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Metastatic Lip Carcinoma

MedGen UID:
1652001
•Concept ID:
C4744558
•
Neoplastic Process

Definition

A carcinoma that arises from the lip and has metastasized to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Lip Carcinoma

Professional guidelines

PubMed

Lower lip basal cell and squamous cell carcinomas: a reappraisal of the similarities and differences in clinical presentation and management.
Hwang JR, Khachemoune A
Arch Dermatol Res 2023 Mar;315(2):117-125. Epub 2022 Mar 21 doi: 10.1007/s00403-022-02345-z. PMID: 35312855
Lip cancer: Reconsidering the at-risk patients with pathological assessment.
Ant A, Kilic C, Baltu Y, Duran AB, Tunccan T, Ozlugedik S, Bozdogan N
Oral Dis 2019 Apr;25(3):742-749. Epub 2019 Jan 23 doi: 10.1111/odi.13017. PMID: 30548899
The place of interstitial therapy using 192 iridium in the management of carcinoma of the lip.
Pigneux J, Richaud PM, Lagarde C
Cancer 1979 Mar;43(3):1073-7. doi: 10.1002/1097-0142(197903)43:3<1073::aid-cncr2820430343>3.0.co;2-8. PMID: 427714

Recent clinical studies

Etiology

Short-term recurrence and distant metastasis following robotic-assisted radical hysterectomy with pelvic lymphadenectomy and chemoradiotherapy for a stage IB1 cervical adenocarcinoma: A case report and literature review.
Tong J, Yu H, Li J, Zhou J, Ma X, Yang J
Medicine (Baltimore) 2019 Apr;98(17):e15387. doi: 10.1097/MD.0000000000015387. PMID: 31027131Free PMC Article
Living with oral cancer: epidemiology with particular reference to prevalence and life-style changes that influence survival.
Warnakulasuriya S
Oral Oncol 2010 Jun;46(6):407-10. Epub 2010 Apr 18 doi: 10.1016/j.oraloncology.2010.02.015. PMID: 20403722
Primary adenoid squamous cell carcinoma of the upper lip associated with a locoregional metastasis: a case report and review of the literature.
Blackburn TK, Macpherson D, Conroy B
J Oral Maxillofac Surg 1999 May;57(5):612-6. doi: 10.1016/s0278-2391(99)90086-1. PMID: 10319839
Squamous cell carcinoma of the skin (excluding lip and oral mucosa).
Johnson TM, Rowe DE, Nelson BR, Swanson NA
J Am Acad Dermatol 1992 Mar;26(3 Pt 2):467-84. doi: 10.1016/0190-9622(92)70074-p. PMID: 1564155
Carcinoma of the lip.
Wurman LH, Adams GL, Meyerhoff WL
Am J Surg 1975 Oct;130(4):470-4. doi: 10.1016/0002-9610(75)90486-9. PMID: 1101725

Diagnosis

Head and Neck Cancer Incidence in the United States Before and During the COVID-19 Pandemic.
Semprini J, Pagedar NA, Boakye EA, Osazuwa-Peters N
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):193-200. doi: 10.1001/jamaoto.2023.4322. PMID: 38206603Free PMC Article
Paraneoplastic vitelliform maculopathy secondary to squamous cell carcinoma of the lip.
Ouederni M, Nefaa F, Chakroun H, Maamouri R, Cheour M
J Fr Ophtalmol 2022 Feb;45(2):255-258. Epub 2021 Dec 27 doi: 10.1016/j.jfo.2021.08.027. PMID: 34969547
Metastatic renal clear cell carcinoma masquerading as a pyogenic granuloma on the lip.
Williams J, Depcik-Smith N, Williams T, Feldman SR
Dermatol Online J 2021 Nov 15;27(11) doi: 10.5070/D3271156090. PMID: 35130402
Short-term recurrence and distant metastasis following robotic-assisted radical hysterectomy with pelvic lymphadenectomy and chemoradiotherapy for a stage IB1 cervical adenocarcinoma: A case report and literature review.
Tong J, Yu H, Li J, Zhou J, Ma X, Yang J
Medicine (Baltimore) 2019 Apr;98(17):e15387. doi: 10.1097/MD.0000000000015387. PMID: 31027131Free PMC Article
Exogenous Lipoid Pneumonia in Laryngectomy Patients: Radiological Findings.
García Latorre R, Rodríguez Díaz R, Barrios Barreto D, Ayala Carbonero A, García Gómez-Muriel MI, Gorospe Sarasúa L
Arch Bronconeumol 2015 Jul;51(7):e36-9. Epub 2014 Oct 23 doi: 10.1016/j.arbres.2014.09.002. PMID: 25446870

Therapy

Mucosa Does Not Matter: Successful Secondary Intention Healing of the Lip and Vermilion Border in Mohs Surgery Patients.
Brahe C, Wu S, Miladi A
Dermatol Surg 2021 May 1;47(5):692-694. doi: 10.1097/DSS.0000000000002335. PMID: 32028481
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL
J Immunother Cancer 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5. PMID: 31307547Free PMC Article
Lung squamous carcinoma involving the lip and cheek.
Yan B, Wu F, Yang N, Zhang Y
Lancet Oncol 2018 Dec;19(12):e726. doi: 10.1016/S1470-2045(18)30441-8. PMID: 30507439
Exogenous Lipoid Pneumonia in Laryngectomy Patients: Radiological Findings.
García Latorre R, Rodríguez Díaz R, Barrios Barreto D, Ayala Carbonero A, García Gómez-Muriel MI, Gorospe Sarasúa L
Arch Bronconeumol 2015 Jul;51(7):e36-9. Epub 2014 Oct 23 doi: 10.1016/j.arbres.2014.09.002. PMID: 25446870
Carcinoma of the lip.
Wurman LH, Adams GL, Meyerhoff WL
Am J Surg 1975 Oct;130(4):470-4. doi: 10.1016/0002-9610(75)90486-9. PMID: 1101725

Prognosis

Head and Neck Cancer Incidence in the United States Before and During the COVID-19 Pandemic.
Semprini J, Pagedar NA, Boakye EA, Osazuwa-Peters N
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):193-200. doi: 10.1001/jamaoto.2023.4322. PMID: 38206603Free PMC Article
Short-term recurrence and distant metastasis following robotic-assisted radical hysterectomy with pelvic lymphadenectomy and chemoradiotherapy for a stage IB1 cervical adenocarcinoma: A case report and literature review.
Tong J, Yu H, Li J, Zhou J, Ma X, Yang J
Medicine (Baltimore) 2019 Apr;98(17):e15387. doi: 10.1097/MD.0000000000015387. PMID: 31027131Free PMC Article
Living with oral cancer: epidemiology with particular reference to prevalence and life-style changes that influence survival.
Warnakulasuriya S
Oral Oncol 2010 Jun;46(6):407-10. Epub 2010 Apr 18 doi: 10.1016/j.oraloncology.2010.02.015. PMID: 20403722
Primary adenoid squamous cell carcinoma of the upper lip associated with a locoregional metastasis: a case report and review of the literature.
Blackburn TK, Macpherson D, Conroy B
J Oral Maxillofac Surg 1999 May;57(5):612-6. doi: 10.1016/s0278-2391(99)90086-1. PMID: 10319839
Squamous cell carcinoma of the skin (excluding lip and oral mucosa).
Johnson TM, Rowe DE, Nelson BR, Swanson NA
J Am Acad Dermatol 1992 Mar;26(3 Pt 2):467-84. doi: 10.1016/0190-9622(92)70074-p. PMID: 1564155

Clinical prediction guides

Head and Neck Cancer Incidence in the United States Before and During the COVID-19 Pandemic.
Semprini J, Pagedar NA, Boakye EA, Osazuwa-Peters N
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):193-200. doi: 10.1001/jamaoto.2023.4322. PMID: 38206603Free PMC Article
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL
J Immunother Cancer 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5. PMID: 31307547Free PMC Article
Squamous cell carcinoma of the lip after allogeneic hemopoietic stem cell transplantation.
Hamadah I, Binamer Y, Alajlan S, Nassar A, Saleh AJ
Hematol Oncol Stem Cell Ther 2010;3(2):84-8. doi: 10.1016/s1658-3876(10)50040-2. PMID: 20543542
Metastases from squamous cell carcinoma of the skin and lip. An analysis of twenty-seven cases.
Dinehart SM, Pollack SV
J Am Acad Dermatol 1989 Aug;21(2 Pt 1):241-8. doi: 10.1016/s0190-9622(89)70168-7. PMID: 2768574
Some observations on the deposition of metastatic carcinoma within cervical lymph nodes.
TOKER C
Cancer 1963 Mar;16:364-74. doi: 10.1002/1097-0142(196303)16:3<364::aid-cncr2820160311>3.0.co;2-k. PMID: 13985306

Recent systematic reviews

Rate of occult metastasis in lip squamous cell carcinoma: A systematic review and meta-analysis.
Kansara S, Oral E, Sarkar I, Sandulache V, Mualla R, Walvekar RR, Ryan W, Ha P
Head Neck 2024 Oct;46(10):2517-2523. Epub 2024 Mar 18 doi: 10.1002/hed.27747. PMID: 38497534
Cribriform adenocarcinoma of the tongue and minor salivary glands: a systematic review of an uncommon clinicopathological entity.
De Luca P, Tassone D, de Campora L, Simone M, Marra P, Colacurcio V, Scarpa A, Costarelli L, Camaioni A
Eur Arch Otorhinolaryngol 2022 Jun;279(6):2719-2725. Epub 2021 Oct 23 doi: 10.1007/s00405-021-07140-6. PMID: 34687340
Immunohistochemical analysis of epithelium adjacent to lip cancer: A meta-analysis.
Varela-Centelles P, Gonzalez-Moles MÁ, Seoane-Romero J, Leira-Feijoo Y, Takkouche B, Seoane-Romero JM
Oral Dis 2022 Jan;28(1):57-65. Epub 2020 Oct 5 doi: 10.1111/odi.13643. PMID: 32945581
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions.
Walsh T, Macey R, Kerr AR, Lingen MW, Ogden GR, Warnakulasuriya S
Cochrane Database Syst Rev 2021 Jul 20;7(7):CD010276. doi: 10.1002/14651858.CD010276.pub3. PMID: 34282854Free PMC Article
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions.
Macey R, Walsh T, Brocklehurst P, Kerr AR, Liu JL, Lingen MW, Ogden GR, Warnakulasuriya S, Scully C
Cochrane Database Syst Rev 2015 May 29;2015(5):CD010276. doi: 10.1002/14651858.CD010276.pub2. PMID: 26021841Free PMC Article

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