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Metastatic Colorectal Adenocarcinoma

MedGen UID:
1693675
Concept ID:
C5205734
Neoplastic Process

Definition

Colorectal adenocarcinoma that has spread from the original site of growth to other anatomic sites. [from NCI]

Professional guidelines

PubMed

Malouf P, Gibbs P, Shapiro J, Sockler J, Bell S
ANZ J Surg 2018 Jan;88(1-2):71-76. Epub 2016 Apr 28 doi: 10.1111/ans.13619. PMID: 27122066
Frizelle FA, McCall JL, Robinson BA
N Z Med J 1998 Jul 10;111(1069):241-4. PMID: 9695758
Quebbeman E, Ausman R, Hansen R, Becker T, Caballero G, Ritch P, Jenkins D, Blake D, Tangen L, Schulte W
J Surg Oncol 1985 Sep;30(1):60-5. doi: 10.1002/jso.2930300115. PMID: 3935873

Recent clinical studies

Etiology

Schleimer LE, Hakki L, Seier K, Seo SK, Cohen N, Usiak S, Romero T, Kamboj M, Ilagan C, Saadat LV, Alessandris R, Soares KC, Drebin J, Wei AC, Widmar M, Wei IH, Smith JJ, Pappou EP, Paty PB, Nash GM, Jarnagin WR, Garcia-Aguilar J, Gonen M, Kingham TP, Weiser MR, D'Angelica MI
Ann Surg Oncol 2025 Feb;32(2):1043-1053. Epub 2024 Nov 21 doi: 10.1245/s10434-024-16489-x. PMID: 39570297
Dasari A, Lonardi S, Garcia-Carbonero R, Elez E, Yoshino T, Sobrero A, Yao J, García-Alfonso P, Kocsis J, Cubillo Gracian A, Sartore-Bianchi A, Satoh T, Randrian V, Tomasek J, Chong G, Paulson AS, Masuishi T, Jones J, Csőszi T, Cremolini C, Ghiringhelli F, Shergill A, Hochster HS, Krauss J, Bassam A, Ducreux M, Elme A, Faugeras L, Kasper S, Van Cutsem E, Arnold D, Nanda S, Yang Z, Schelman WR, Kania M, Tabernero J, Eng C; FRESCO-2 Study Investigators
Lancet 2023 Jul 1;402(10395):41-53. Epub 2023 Jun 15 doi: 10.1016/S0140-6736(23)00772-9. PMID: 37331369
Roy S, Smith MA, Cieply KM, Acquafondata MB, Parwani AV
Diagn Pathol 2012 Nov 2;7:151. doi: 10.1186/1746-1596-7-151. PMID: 23121893Free PMC Article
Petrelli NJ, Rustum YM, Bruckner H, Stablein D
Adv Exp Med Biol 1988;244:143-55. doi: 10.1007/978-1-4684-5607-3_15. PMID: 3073651
Vassilopoulos PP, Ledesma EJ, Yoon JM, Jung O, Mittelman A
Dis Colon Rectum 1981 May-Jun;24(4):265-71. doi: 10.1007/BF02641874. PMID: 7238236

Diagnosis

McHugh KE, Dermawan JK, Cheng YW, Cruise M, Sohal DPS, Reynolds JP
Diagn Cytopathol 2019 Nov;47(11):1132-1137. Epub 2019 Jul 9 doi: 10.1002/dc.24275. PMID: 31290252
Waters KM, Cottrell TR, Besharati S, Zhu Q, Anders RA
Am J Clin Pathol 2019 Jan 7;151(2):226-230. doi: 10.1093/ajcp/aqy134. PMID: 30339201Free PMC Article
Huynh F, McLean C, Smith M
ANZ J Surg 2019 Oct;89(10):1330-1332. Epub 2018 Jun 27 doi: 10.1111/ans.14705. PMID: 29952067
Marks EI, Brennan M, El-Deiry WS
Cancer Biol Ther 2015;16(8):1136-9. doi: 10.1080/15384047.2015.1057360. PMID: 26047368Free PMC Article
Roy S, Smith MA, Cieply KM, Acquafondata MB, Parwani AV
Diagn Pathol 2012 Nov 2;7:151. doi: 10.1186/1746-1596-7-151. PMID: 23121893Free PMC Article

Therapy

Boland PM, Mukherjee S, Imanirad I, Vijayvergia N, Cohen SD, Gupta M, Iyer RV, Bakin A, Wang J, Chatley S, Cahill B, Vadehra D, Attwood K, Hochster HS, Fountzilas C
Br J Cancer 2024 Nov;131(8):1290-1297. Epub 2024 Sep 7 doi: 10.1038/s41416-024-02845-x. PMID: 39244627Free PMC Article
Dasari A, Lonardi S, Garcia-Carbonero R, Elez E, Yoshino T, Sobrero A, Yao J, García-Alfonso P, Kocsis J, Cubillo Gracian A, Sartore-Bianchi A, Satoh T, Randrian V, Tomasek J, Chong G, Paulson AS, Masuishi T, Jones J, Csőszi T, Cremolini C, Ghiringhelli F, Shergill A, Hochster HS, Krauss J, Bassam A, Ducreux M, Elme A, Faugeras L, Kasper S, Van Cutsem E, Arnold D, Nanda S, Yang Z, Schelman WR, Kania M, Tabernero J, Eng C; FRESCO-2 Study Investigators
Lancet 2023 Jul 1;402(10395):41-53. Epub 2023 Jun 15 doi: 10.1016/S0140-6736(23)00772-9. PMID: 37331369
Cleary JM, Tanabe KT, Lauwers GY, Zhu AX
Oncologist 2009 Nov;14(11):1095-105. Epub 2009 Oct 30 doi: 10.1634/theoncologist.2009-0152. PMID: 19880627
Lai JI, Wang WS
Pharm World Sci 2009 Oct;31(5):538-541. Epub 2009 Jul 9 doi: 10.1007/s11096-009-9313-0. PMID: 19588266
Frizelle FA, McCall JL, Robinson BA
N Z Med J 1998 Jul 10;111(1069):241-4. PMID: 9695758

Prognosis

Tbeileh N, Timmerman L, Mattis AN, Toriguchi K, Kasai Y, Corvera C, Nakakura E, Hirose K, Donner DB, Warren RS, Karelehto E
PLoS One 2023;18(4):e0271354. Epub 2023 Apr 6 doi: 10.1371/journal.pone.0271354. PMID: 37022995Free PMC Article
Golan T, Urban D, Berger R, Lawrence YR
Cancer 2013 Aug 15;119(16):3084-91. Epub 2013 May 29 doi: 10.1002/cncr.28143. PMID: 23720150
Roy S, Smith MA, Cieply KM, Acquafondata MB, Parwani AV
Diagn Pathol 2012 Nov 2;7:151. doi: 10.1186/1746-1596-7-151. PMID: 23121893Free PMC Article
Petrelli NJ, Madajewicz S, Herrera L, Rustum YM, Trave F, Creaven P, Mittelman A
NCI Monogr 1987;(5):189-92. PMID: 3501541
Vassilopoulos PP, Ledesma EJ, Yoon JM, Jung O, Mittelman A
Dis Colon Rectum 1981 May-Jun;24(4):265-71. doi: 10.1007/BF02641874. PMID: 7238236

Clinical prediction guides

Davar D, Cavalcante L, Lakhani N, Moser J, Millward M, McKean M, Voskoboynik M, Sanborn RE, Grewal JS, Narayan A, Patnaik A, Gainor JF, Sznol M, Enstrom A, Blanchfield L, LeBlanc H, Thomas H, Chisamore MJ, Peng SL, Naumovski A
J Immunother Cancer 2024 Aug 3;12(8) doi: 10.1136/jitc-2024-009474. PMID: 39097413Free PMC Article
Tbeileh N, Timmerman L, Mattis AN, Toriguchi K, Kasai Y, Corvera C, Nakakura E, Hirose K, Donner DB, Warren RS, Karelehto E
PLoS One 2023;18(4):e0271354. Epub 2023 Apr 6 doi: 10.1371/journal.pone.0271354. PMID: 37022995Free PMC Article
Fountzilas C, Bajor DL, Mukherjee S, Saltzman J, Witkiewicz AK, Maguire O, Minderman H, Nambiar R, Rosenheck HR, Knudsen ES, Muhitch JB, Abrams SI, Wang C, Hutson AD, Attwood K, Hicks KA, Jurcevic JA, Kalinski P, Iyer R, Boland PM
Clin Cancer Res 2021 Dec 15;27(24):6726-6736. Epub 2021 Oct 13 doi: 10.1158/1078-0432.CCR-21-1650. PMID: 34645646Free PMC Article
Roy S, Smith MA, Cieply KM, Acquafondata MB, Parwani AV
Diagn Pathol 2012 Nov 2;7:151. doi: 10.1186/1746-1596-7-151. PMID: 23121893Free PMC Article
Rose JS, Serna DS, Martin LK, Li X, Weatherby LM, Abdel-Misih S, Zhao W, Bekaii-Saab T
Cancer 2012 Dec 15;118(24):6243-52. Epub 2012 Jun 6 doi: 10.1002/cncr.27666. PMID: 22674181Free PMC Article

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