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Trichoblastic Carcinosarcoma

MedGen UID:
1712494
•Concept ID:
C5238509
•
Neoplastic Process
Synonym: Trichoblastic carcinosarcoma
SNOMED CT: Trichoblastic carcinosarcoma (1290921008)

Definition

A rare biphasic follicular neoplasm consisting of a malignant epithelial component resembling follicular germinative cells closely associated with a malignant stromal component differentiating towards specific follicular mesenchyme. (WHO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTrichoblastic Carcinosarcoma

Recent clinical studies

Diagnosis

Trichoblastic carcinosarcoma of the neck: Case report and molecular analysis of a seldom, relapsing entity and a review of the literature.
Weiland T, Sadoghi B, Pondorfer P, Kiss P, Brcic I, Thurnher D
J Dermatol 2023 May;50(5):700-704. Epub 2023 Jan 18 doi: 10.1111/1346-8138.16716. PMID: 36651105
Trichoblastic Carcinosarcoma Arising From the Vagina: A Case Report With Comprehensive Immunophenotypic Analysis.
Li JJX, Ng JKM, Choi PCL, Lee JHS, Yu MY
Int J Surg Pathol 2020 Jun;28(4):440-446. Epub 2019 Nov 20 doi: 10.1177/1066896919887803. PMID: 31747847
Trichoblastic carcinosarcoma: A case report and literature review.
Underwood CIM, Mansoori P, Selim AM, Al-Rohil RN
J Cutan Pathol 2020 Apr;47(4):409-413. Epub 2019 Nov 28 doi: 10.1111/cup.13614. PMID: 31730287
Trichoblastic Carcinosarcoma of the Skin: A Case Report and Literature Review.
Okhremchuk I, Nguyen AT, Fouet B, Morand JJ
Am J Dermatopathol 2018 Dec;40(12):917-919. doi: 10.1097/DAD.0000000000001213. PMID: 29933313
High-grade trichoblastic carcinosarcoma.
Kazakov DV, Vittay G, Michal M, Calonje E
Am J Dermatopathol 2008 Feb;30(1):62-4. doi: 10.1097/DAD.0b013e31815c6c7f. PMID: 18212548

Prognosis

Trichoblastic carcinosarcoma: A case report and literature review.
Underwood CIM, Mansoori P, Selim AM, Al-Rohil RN
J Cutan Pathol 2020 Apr;47(4):409-413. Epub 2019 Nov 28 doi: 10.1111/cup.13614. PMID: 31730287

Clinical prediction guides

Low-grade trichoblastic carcinosarcoma of the skin.
Kazakov DV, Kempf W, Michal M
Am J Dermatopathol 2004 Aug;26(4):304-9. doi: 10.1097/00000372-200408000-00007. PMID: 15249861

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