U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Locally Advanced Fallopian Tube Carcinoma

MedGen UID:
1720192
•Concept ID:
C5238359
•
Neoplastic Process

Definition

Fallopian tube carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Fallopian Tube Carcinoma

Professional guidelines

PubMed

Frontline Maintenance Treatment for Ovarian Cancer.
Elyashiv O, Wong YNS, Ledermann JA
Curr Oncol Rep 2021 Jun 14;23(8):97. doi: 10.1007/s11912-021-01088-w. PMID: 34125335Free PMC Article
Chemotherapy for epithelial ovarian, fallopian tube and primary peritoneal cancer.
Webber K, Friedlander M
Best Pract Res Clin Obstet Gynaecol 2017 May;41:126-138. Epub 2016 Nov 23 doi: 10.1016/j.bpobgyn.2016.11.004. PMID: 28027849
Current management of fallopian tube carcinoma.
Gadducci A
Curr Opin Obstet Gynecol 2002 Feb;14(1):27-32. doi: 10.1097/00001703-200202000-00005. PMID: 11801873

Recent clinical studies

Etiology

Mirvetuximab soravtansine-gynx: first antibody/antigen-drug conjugate (ADC) in advanced or recurrent ovarian cancer.
Bogani G, Coleman RL, Vergote I, van Gorp T, Ray-Coquard I, Oaknin A, Matulonis U, O'Malley D, Raspagliesi F, Scambia G, Monk BJ
Int J Gynecol Cancer 2024 Apr 1;34(4):469-477. doi: 10.1136/ijgc-2023-004924. PMID: 38101816
Genomic catastrophe, the peritoneal cavity and ovarian cancer prevention.
Yoon JY, Chapel DB, Goebel E, Qian X, Mito JK, Horowitz NS, Miron A, Soong TR, Xian W, Crum CP
J Pathol 2022 Jul;257(3):255-261. Epub 2022 Apr 18 doi: 10.1002/path.5891. PMID: 35238033
Objective responses to first-line neoadjuvant carboplatin-paclitaxel regimens for ovarian, fallopian tube, or primary peritoneal carcinoma (ICON8): post-hoc exploratory analysis of a randomised, phase 3 trial.
Morgan RD, McNeish IA, Cook AD, James EC, Lord R, Dark G, Glasspool RM, Krell J, Parkinson C, Poole CJ, Hall M, Gallardo-Rincón D, Lockley M, Essapen S, Summers J, Anand A, Zachariah A, Williams S, Jones R, Scatchard K, Walther A, Kim JW, Sundar S, Jayson GC, Ledermann JA, Clamp AR
Lancet Oncol 2021 Feb;22(2):277-288. Epub 2020 Dec 22 doi: 10.1016/S1470-2045(20)30591-X. PMID: 33357510Free PMC Article
Personalized cancer treatment for ovarian cancer.
Chumworathayi B
Asian Pac J Cancer Prev 2013;14(3):1661-4. doi: 10.7314/apjcp.2013.14.3.1661. PMID: 23679252
Current management of fallopian tube carcinoma.
Gadducci A
Curr Opin Obstet Gynecol 2002 Feb;14(1):27-32. doi: 10.1097/00001703-200202000-00005. PMID: 11801873

Diagnosis

Mirvetuximab soravtansine-gynx: first antibody/antigen-drug conjugate (ADC) in advanced or recurrent ovarian cancer.
Bogani G, Coleman RL, Vergote I, van Gorp T, Ray-Coquard I, Oaknin A, Matulonis U, O'Malley D, Raspagliesi F, Scambia G, Monk BJ
Int J Gynecol Cancer 2024 Apr 1;34(4):469-477. doi: 10.1136/ijgc-2023-004924. PMID: 38101816
Mutant p53 murine oviductal epithelial cells induce progression of high-grade serous carcinoma and are most sensitive to simvastatin therapy in vitro and in vivo.
Pereira M, Glogova A, Haagsma J, Stewart J, Shepherd TG, Petrik J
J Ovarian Res 2023 Nov 20;16(1):218. doi: 10.1186/s13048-023-01307-x. PMID: 37986175Free PMC Article
Chemotherapy for epithelial ovarian, fallopian tube and primary peritoneal cancer.
Webber K, Friedlander M
Best Pract Res Clin Obstet Gynaecol 2017 May;41:126-138. Epub 2016 Nov 23 doi: 10.1016/j.bpobgyn.2016.11.004. PMID: 28027849
Bevacizumab in Ovarian Cancer: State of the Art and Unanswered Questions.
Musella A, Vertechy L, Romito A, Marchetti C, Giannini A, Sciuga V, Bracchi C, Tomao F, Di Donato V, De Felice F, Monti M, Muzii L, Benedetti Panici P
Chemotherapy 2017;62(2):111-120. Epub 2016 Oct 29 doi: 10.1159/000448942. PMID: 27794568
The changing landscape of therapeutic strategies for recurrent ovarian cancer.
Baumann KH, Wagner U, du Bois A
Future Oncol 2012 Sep;8(9):1135-47. doi: 10.2217/fon.12.112. PMID: 23030488

Therapy

Mirvetuximab soravtansine-gynx: first antibody/antigen-drug conjugate (ADC) in advanced or recurrent ovarian cancer.
Bogani G, Coleman RL, Vergote I, van Gorp T, Ray-Coquard I, Oaknin A, Matulonis U, O'Malley D, Raspagliesi F, Scambia G, Monk BJ
Int J Gynecol Cancer 2024 Apr 1;34(4):469-477. doi: 10.1136/ijgc-2023-004924. PMID: 38101816
Frontline Maintenance Treatment for Ovarian Cancer.
Elyashiv O, Wong YNS, Ledermann JA
Curr Oncol Rep 2021 Jun 14;23(8):97. doi: 10.1007/s11912-021-01088-w. PMID: 34125335Free PMC Article
Chemotherapy for epithelial ovarian, fallopian tube and primary peritoneal cancer.
Webber K, Friedlander M
Best Pract Res Clin Obstet Gynaecol 2017 May;41:126-138. Epub 2016 Nov 23 doi: 10.1016/j.bpobgyn.2016.11.004. PMID: 28027849
Bevacizumab in Ovarian Cancer: State of the Art and Unanswered Questions.
Musella A, Vertechy L, Romito A, Marchetti C, Giannini A, Sciuga V, Bracchi C, Tomao F, Di Donato V, De Felice F, Monti M, Muzii L, Benedetti Panici P
Chemotherapy 2017;62(2):111-120. Epub 2016 Oct 29 doi: 10.1159/000448942. PMID: 27794568
Personalized cancer treatment for ovarian cancer.
Chumworathayi B
Asian Pac J Cancer Prev 2013;14(3):1661-4. doi: 10.7314/apjcp.2013.14.3.1661. PMID: 23679252

Prognosis

Objective responses to first-line neoadjuvant carboplatin-paclitaxel regimens for ovarian, fallopian tube, or primary peritoneal carcinoma (ICON8): post-hoc exploratory analysis of a randomised, phase 3 trial.
Morgan RD, McNeish IA, Cook AD, James EC, Lord R, Dark G, Glasspool RM, Krell J, Parkinson C, Poole CJ, Hall M, Gallardo-Rincón D, Lockley M, Essapen S, Summers J, Anand A, Zachariah A, Williams S, Jones R, Scatchard K, Walther A, Kim JW, Sundar S, Jayson GC, Ledermann JA, Clamp AR
Lancet Oncol 2021 Feb;22(2):277-288. Epub 2020 Dec 22 doi: 10.1016/S1470-2045(20)30591-X. PMID: 33357510Free PMC Article
Outcome and Prognostic Impact of Surgical Staging in Serous Tubal Intraepithelial Carcinoma: A Cohort Study and Systematic Review.
Van der Hoeven NMA, Van Wijk K, Bonfrer SE, Beltman JJ, Louwe LA, De Kroon CD, Van Asperen CJ, Gaarenstroom KN
Clin Oncol (R Coll Radiol) 2018 Aug;30(8):463-471. Epub 2018 Apr 22 doi: 10.1016/j.clon.2018.03.036. PMID: 29691126
Bevacizumab in Ovarian Cancer: State of the Art and Unanswered Questions.
Musella A, Vertechy L, Romito A, Marchetti C, Giannini A, Sciuga V, Bracchi C, Tomao F, Di Donato V, De Felice F, Monti M, Muzii L, Benedetti Panici P
Chemotherapy 2017;62(2):111-120. Epub 2016 Oct 29 doi: 10.1159/000448942. PMID: 27794568
Personalized cancer treatment for ovarian cancer.
Chumworathayi B
Asian Pac J Cancer Prev 2013;14(3):1661-4. doi: 10.7314/apjcp.2013.14.3.1661. PMID: 23679252
The changing landscape of therapeutic strategies for recurrent ovarian cancer.
Baumann KH, Wagner U, du Bois A
Future Oncol 2012 Sep;8(9):1135-47. doi: 10.2217/fon.12.112. PMID: 23030488

Clinical prediction guides

Comparison of treatment outcomes between first-line chemotherapy with or without bevacizumab for advanced ovarian, fallopian tube, and primary peritoneal cancer (Tohoku gynecologic cancer unit: TGCU-RS001 study).
Shoji T, Takatori E, Nagasawa T, Kagabu M, Baba T, Shigeto T, Matsumura Y, Shimizu D, Terada Y, Seino M, Ohta T, Nagase S, Shigeta S, Tokunaga H, Shimada M, Kaiho-Sakuma M, Furukawa S, Soeda S, Watanabe T, Takahashi F, Yokoyama Y
Int J Clin Oncol 2022 Dec;27(12):1874-1880. Epub 2022 Oct 10 doi: 10.1007/s10147-022-02246-1. PMID: 36214925
Genomic catastrophe, the peritoneal cavity and ovarian cancer prevention.
Yoon JY, Chapel DB, Goebel E, Qian X, Mito JK, Horowitz NS, Miron A, Soong TR, Xian W, Crum CP
J Pathol 2022 Jul;257(3):255-261. Epub 2022 Apr 18 doi: 10.1002/path.5891. PMID: 35238033
Objective responses to first-line neoadjuvant carboplatin-paclitaxel regimens for ovarian, fallopian tube, or primary peritoneal carcinoma (ICON8): post-hoc exploratory analysis of a randomised, phase 3 trial.
Morgan RD, McNeish IA, Cook AD, James EC, Lord R, Dark G, Glasspool RM, Krell J, Parkinson C, Poole CJ, Hall M, Gallardo-Rincón D, Lockley M, Essapen S, Summers J, Anand A, Zachariah A, Williams S, Jones R, Scatchard K, Walther A, Kim JW, Sundar S, Jayson GC, Ledermann JA, Clamp AR
Lancet Oncol 2021 Feb;22(2):277-288. Epub 2020 Dec 22 doi: 10.1016/S1470-2045(20)30591-X. PMID: 33357510Free PMC Article
A comparison of outcomes following total and selective peritonectomy performed at the time of interval cytoreductive surgery for advanced serous epithelial ovarian, fallopian tube and primary peritoneal cancer - A study by INDEPSO.
Sinukumar S, Rajan F, Mehta S, Damodaran D, Zaveri S, Kammar P, Bhatt A
Eur J Surg Oncol 2021 Jan;47(1):75-81. Epub 2019 Feb 23 doi: 10.1016/j.ejso.2019.02.031. PMID: 30857879
Recurrence patterns of advanced ovarian, fallopian tube, and peritoneal cancers after complete cytoreduction during interval debulking surgery.
Usami T, Kato K, Taniguchi T, Abe A, Nomura H, Yamamoto A, Matoda M, Okamoto S, Kondo E, Omatsu K, Kawamata Y, Takeshima N
Int J Gynecol Cancer 2014 Jul;24(6):991-6. doi: 10.1097/IGC.0000000000000142. PMID: 24905612

Recent systematic reviews

The Efficacy and Safety of Folate Receptor α-Targeted Antibody-Drug Conjugate Therapy in Patients With High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers: A Systematic Review and Meta-Analysis.
Kim ET, Kim JH, Park EY, Song IH, Park HS, Park SY, Lim MC
Cancer Med 2024 Nov;13(21):e70392. doi: 10.1002/cam4.70392. PMID: 39526448Free PMC Article
Extra-abdominal ovarian cancer presenting with breast metastases at diagnosis: Case report and literature review.
Ferrari F, Ficarelli S, Forte S, Valenti G, Ardighieri L, Sartori E, Odicino F
Eur J Obstet Gynecol Reprod Biol 2020 Dec;255:211-221. Epub 2020 Oct 12 doi: 10.1016/j.ejogrb.2020.10.004. PMID: 33152565
Outcome and Prognostic Impact of Surgical Staging in Serous Tubal Intraepithelial Carcinoma: A Cohort Study and Systematic Review.
Van der Hoeven NMA, Van Wijk K, Bonfrer SE, Beltman JJ, Louwe LA, De Kroon CD, Van Asperen CJ, Gaarenstroom KN
Clin Oncol (R Coll Radiol) 2018 Aug;30(8):463-471. Epub 2018 Apr 22 doi: 10.1016/j.clon.2018.03.036. PMID: 29691126

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...