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Pituitary gland acidophil adenoma

MedGen UID:
1748
•Concept ID:
C0001433
•
Neoplastic Process
Synonyms: Acidophil Adenoma; Acidophil Adenomas; Acidophilic Adenoma; Acidophilic Adenomas; Adenoma, Acidophil; Adenoma, Acidophilic; Adenoma, Eosinophil; Adenoma, Eosinophilic; Adenomas, Acidophil; Adenomas, Acidophilic; Adenomas, Eosinophil; Adenomas, Eosinophilic; Eosinophil Adenoma; Eosinophil Adenomas; Eosinophilic Adenoma; Eosinophilic Adenomas
 
Monarch Initiative: MONDO:0006634

Definition

An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells stain positive with acidic dyes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary gland acidophil adenoma

Professional guidelines

PubMed

Letter: Treatment of acromegaly.
Maroon JC, Robinson AG, Kennerdell JS
Lancet 1975 Jan 25;1(7900):226. doi: 10.1016/s0140-6736(75)91405-1. PMID: 47463
Stereotaxic diagnosis and treatment of intracranial tumors including an initial experience with cryosurgery for pinealomas.
Conway LW
J Neurosurg 1973 Apr;38(4):453-60. doi: 10.3171/jns.1973.38.4.0453. PMID: 4348746
Studies in hypoglycemia of infancy and childhood. Diagnosis and treatment.
Antony GJ, Underwood LE, Van Wyk JJ
Am J Dis Child 1967 Oct;114(4):345-69. doi: 10.1001/archpedi.1967.02090250043001. PMID: 4292629

Recent clinical studies

Etiology

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Gamma Knife radiosurgery as a primary surgical treatment for hypersecreting pituitary adenomas.
Zhang N, Pan L, Dai J, Wang B, Wang E, Zhang W, Cai P
Stereotact Funct Neurosurg 2000;75(2-3):123-8. doi: 10.1159/000048393. PMID: 11740180
A clinicomorphological study of pituitary tumors associated with the clinical syndrome of acromegaly.
Andreeva M, Georgiev T, Bosadjieva E, Karagiosov L, Karagiosov K, Tomova A, Matrosov P, Kirilov G, Diankov L, Christova T
Exp Clin Endocrinol 1991;98(3):223-7. doi: 10.1055/s-0029-1211121. PMID: 1778242
An overview of pituitary tumors.
Berry RG, Caplan HJ
Ann Clin Lab Sci 1979 Mar-Apr;9(2):94-102. PMID: 222198
Pituitary adenomas and craniopharyngiomas: analysis of 99 cases treated with radiation therapy.
Urdaneta N, Chessin H, Fischer JJ
Int J Radiat Oncol Biol Phys 1976 Sep-Oct;1(9-10):895-902. doi: 10.1016/0360-3016(76)90114-0. PMID: 185179

Diagnosis

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Acidophil stem cell pituitary adenoma: a case report and literature review.
Annapurni A, Rathi M
Hormones (Athens) 2019 Dec;18(4):507-512. Epub 2019 Nov 13 doi: 10.1007/s42000-019-00154-0. PMID: 31721135
New treatments for acromegaly.
Wass JA, Sheppard MC
J R Coll Physicians Lond 1998 Mar-Apr;32(2):113-7. PMID: 9597624Free PMC Article
Acromegaly.
Ezzat S
Endocrinol Metab Clin North Am 1997 Dec;26(4):703-23. doi: 10.1016/s0889-8529(05)70278-4. PMID: 9429856
Pituitary apoplexy.
Tsementzis SA, Loizou LA
Neurochirurgia (Stuttg) 1986 May;29(3):90-2. doi: 10.1055/s-2008-1053709. PMID: 3014358

Therapy

New treatments for acromegaly.
Wass JA, Sheppard MC
J R Coll Physicians Lond 1998 Mar-Apr;32(2):113-7. PMID: 9597624Free PMC Article
Space occupying growth of a pituitary adenoma producing hGH and hPrl during bromocriptin therapy.
Halves E
Clin Neurol Neurosurg 1977;80(4):251-7. doi: 10.1016/s0303-8467(78)80015-8. PMID: 216515
Stereotactic Curie-therapy of pituitary adenomas. A long-term follow-up study.
MUNDINGER F
Acta Neurochir (Wien) 1974;Suppl 21:169-76. doi: 10.1007/978-3-7091-8355-7_23. PMID: 4370389
Heavy-particle therapy for acromegaly, Cushing's disease, Nelson's syndrome, and nonfunctioning pituitary adenomas.
Linfoot JA, Chong CY, Garcia JF, Cleveland AS, Connell GM, Manougian E, Okerlund MD, Born JL, Lawrence JH
Prog At Med 1971;3:219-38. PMID: 4335128
The value of radiation therapy for pituitary and parapituitary tumours.
Kramer S
Can Med Assoc J 1968 Dec 14;99(23):1120-7. PMID: 4302128Free PMC Article

Prognosis

Gamma Knife radiosurgery as a primary surgical treatment for hypersecreting pituitary adenomas.
Zhang N, Pan L, Dai J, Wang B, Wang E, Zhang W, Cai P
Stereotact Funct Neurosurg 2000;75(2-3):123-8. doi: 10.1159/000048393. PMID: 11740180
New treatments for acromegaly.
Wass JA, Sheppard MC
J R Coll Physicians Lond 1998 Mar-Apr;32(2):113-7. PMID: 9597624Free PMC Article
Progressive late delayed postirradiation encephalopathy with Klüver-Bucy syndrome. Serial MRI and clinico-pathological studies.
Thajeb P
Clin Neurol Neurosurg 1995 Aug;97(3):264-8. doi: 10.1016/0303-8467(95)00049-p. PMID: 7586863
Dedifferentiation and invasive growth of an eosinophil pituitary adenoma.
Ostertag C, Weitbrecht WU
Acta Neurochir (Wien) 1978;40(1-2):175-9. doi: 10.1007/BF01773125. PMID: 207157
Stereotactic Curie-therapy of pituitary adenomas. A long-term follow-up study.
MUNDINGER F
Acta Neurochir (Wien) 1974;Suppl 21:169-76. doi: 10.1007/978-3-7091-8355-7_23. PMID: 4370389

Clinical prediction guides

Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
Epidemiology and biomarker profile of pituitary adenohypophysial tumors.
Mete O, Cintosun A, Pressman I, Asa SL
Mod Pathol 2018 Jun;31(6):900-909. Epub 2018 Feb 12 doi: 10.1038/s41379-018-0016-8. PMID: 29434339
Clinical Implications of Accurate Subtyping of Pituitary Adenomas: Perspectives from the Treating Physician.
Gomez-Hernandez K, Ezzat S, Asa SL, Mete Ö
Turk Patoloji Derg 2015;31 Suppl 1:4-17. doi: 10.5146/tjpath.2015.01311. PMID: 26177314
Plasma growth hormone half-life after selective removal of adenoma in acromegalics determines the outcome of surgery.
Roelfsema F, van der Heide D, Lowry PJ, van Dulken H, Schröder-van der Elst J
Clin Endocrinol (Oxf) 1988 Jan;28(1):51-9. doi: 10.1111/j.1365-2265.1988.tb01203.x. PMID: 2844444
Dedifferentiation and invasive growth of an eosinophil pituitary adenoma.
Ostertag C, Weitbrecht WU
Acta Neurochir (Wien) 1978;40(1-2):175-9. doi: 10.1007/BF01773125. PMID: 207157

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