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Lymphoma, B-cell, EBV-associated

MedGen UID:
1767418
•Concept ID:
C5436861
•
Neoplastic Process
Synonym: EBV-associated B cell lymphoma

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLymphoma, B-cell, EBV-associated

Professional guidelines

PubMed

Dynamic changes in circulating EBV-DNA load during treatment have prognostic values in EBV(+) DLBCL-NOS: a Chinese cohort study.
Xing TY, Duan ZW, Wang WT, Du KX, Shen HR, Yin H, Wu JZ, Li Y, Wang L, Li JY, Liang JH, Xu W
Ann Hematol 2023 Sep;102(9):2471-2481. Epub 2023 May 10 doi: 10.1007/s00277-023-05260-z. PMID: 37160794
'Off-the-shelf' allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies.
Sinha D, Srihari S, Beckett K, Le Texier L, Solomon M, Panikkar A, Ambalathingal GR, Lekieffre L, Crooks P, Rehan S, Neller MA, Smith C, Khanna R
J Immunother Cancer 2021 Feb;9(2) doi: 10.1136/jitc-2020-001608. PMID: 33589524Free PMC Article
AIDS-related primary pulmonary lymphoma.
Ray P, Antoine M, Mary-Krause M, Lebrette MG, Wislez M, Duvivier C, Meyohas MC, Girard PM, Mayaud C, Cadranel J
Am J Respir Crit Care Med 1998 Oct;158(4):1221-9. doi: 10.1164/ajrccm.158.4.9801057. PMID: 9769285

Recent clinical studies

Etiology

New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Impact of Epstein-Barr virus infection in patients with inflammatory bowel disease.
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Epstein-Barr virus and rheumatoid arthritis.
Balandraud N, Roudier J
Joint Bone Spine 2018 Mar;85(2):165-170. Epub 2017 May 9 doi: 10.1016/j.jbspin.2017.04.011. PMID: 28499895
Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.
Auerbach A, Aguilera NS
Semin Diagn Pathol 2015 Jan;32(1):12-22. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.001. PMID: 25804341
The Epstein-Barr virus and the pathogenesis of lymphoma.
Vockerodt M, Yap LF, Shannon-Lowe C, Curley H, Wei W, Vrzalikova K, Murray PG
J Pathol 2015 Jan;235(2):312-22. doi: 10.1002/path.4459. PMID: 25294567

Diagnosis

EBV-associated lymphoproliferative disease post-CAR-T cell therapy.
Zhang S, Zhou X, Zhang S, Wang N, Zhang T, Zhang D, Ao Q, Cao Y, Huang L
Front Med 2024 Apr;18(2):394-398. Epub 2024 Feb 8 doi: 10.1007/s11684-023-1032-8. PMID: 38329597
New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Impact of Epstein-Barr virus infection in patients with inflammatory bowel disease.
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
EBV-Associated Lymphoproliferative Disorders: Update in Classification.
Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986
Pulmonary lymphoid disorders.
Koss MN
Semin Diagn Pathol 1995 May;12(2):158-71. PMID: 7638448

Therapy

EBV-associated lymphoproliferative disease post-CAR-T cell therapy.
Zhang S, Zhou X, Zhang S, Wang N, Zhang T, Zhang D, Ao Q, Cao Y, Huang L
Front Med 2024 Apr;18(2):394-398. Epub 2024 Feb 8 doi: 10.1007/s11684-023-1032-8. PMID: 38329597
Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study.
Hu Y, Zhou Y, Zhang M, Zhao H, Wei G, Ge W, Cui Q, Mu Q, Chen G, Han L, Guo T, Cui J, Jiang X, Zheng X, Yu S, Li X, Zhang X, Chen M, Li X, Gao M, Wang K, Zu C, Zhang H, He X, Wang Y, Wang D, Ren J, Huang H
Cell Res 2022 Nov;32(11):995-1007. Epub 2022 Sep 23 doi: 10.1038/s41422-022-00721-y. PMID: 36151216Free PMC Article
Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
T-cell therapies for T-cell lymphoma.
Toner K, Bollard CM, Dave H
Cytotherapy 2019 Sep;21(9):935-942. Epub 2019 Jul 16 doi: 10.1016/j.jcyt.2019.04.058. PMID: 31320195
Adoptive cell therapy with donor lymphocytes for EBV-associated lymphomas developing after allogeneic marrow transplants.
O'Reilly RJ, Lacerda JF, Lucas KG, Rosenfield NS, Small TN, Papadopoulos EB
Important Adv Oncol 1996:149-66. PMID: 8791134

Prognosis

Epstein-Barr virus-associated lymphomas decoded.
Bednarska K, Chowdhury R, Tobin JWD, Swain F, Keane C, Boyle S, Khanna R, Gandhi MK
Br J Haematol 2024 Feb;204(2):415-433. Epub 2023 Dec 28 doi: 10.1111/bjh.19255. PMID: 38155519
Epstein-Barr virus-encoded EBNA2 downregulates ICOSL by inducing miR-24 in B-cell lymphoma.
Leopizzi M, Mundo L, Messina E, Campolo F, Lazzi S, Angeloni A, Marchese C, Leoncini L, Giordano C, Slack F, Trivedi P, Anastasiadou E
Blood 2024 Feb 1;143(5):429-443. doi: 10.1182/blood.2023021346. PMID: 37847858Free PMC Article
New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Impact of Epstein-Barr virus infection in patients with inflammatory bowel disease.
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
EBV in T-/NK-Cell Tumorigenesis.
Kimura H
Adv Exp Med Biol 2018;1045:459-475. doi: 10.1007/978-981-10-7230-7_21. PMID: 29896680

Clinical prediction guides

Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study.
Hu Y, Zhou Y, Zhang M, Zhao H, Wei G, Ge W, Cui Q, Mu Q, Chen G, Han L, Guo T, Cui J, Jiang X, Zheng X, Yu S, Li X, Zhang X, Chen M, Li X, Gao M, Wang K, Zu C, Zhang H, He X, Wang Y, Wang D, Ren J, Huang H
Cell Res 2022 Nov;32(11):995-1007. Epub 2022 Sep 23 doi: 10.1038/s41422-022-00721-y. PMID: 36151216Free PMC Article
Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
Defective Epstein-Barr virus in chronic active infection and haematological malignancy.
Okuno Y, Murata T, Sato Y, Muramatsu H, Ito Y, Watanabe T, Okuno T, Murakami N, Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Narita Y, Yoshida M, Goshima F, Kawada JI, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H
Nat Microbiol 2019 Mar;4(3):404-413. Epub 2019 Jan 21 doi: 10.1038/s41564-018-0334-0. PMID: 30664667
Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.
Auerbach A, Aguilera NS
Semin Diagn Pathol 2015 Jan;32(1):12-22. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.001. PMID: 25804341
The Epstein-Barr virus and the pathogenesis of lymphoma.
Vockerodt M, Yap LF, Shannon-Lowe C, Curley H, Wei W, Vrzalikova K, Murray PG
J Pathol 2015 Jan;235(2):312-22. doi: 10.1002/path.4459. PMID: 25294567

Recent systematic reviews

Post-transplant lymphoproliferative disorders after allogeneic hematopoietic stem cell transplantation: a case report, meta-analysis, and systematic review.
Su YY, Yu YF, Yan ZY, Zhao YJ, Lou JW, Xue F, Xu M, Feng Q, Ji XB, Dong XY, Wang W, Liu CF, Peng J, Liu XG
Diagn Pathol 2024 Sep 7;19(1):122. doi: 10.1186/s13000-024-01544-8. PMID: 39244586Free PMC Article
Risk factors for Epstein Barr virus-associated cancers: a systematic review, critical appraisal, and mapping of the epidemiological evidence.
Bakkalci D, Jia Y, Winter JR, Lewis JE, Taylor GS, Stagg HR
J Glob Health 2020 Jun;10(1):010405. doi: 10.7189/jogh.10.010405. PMID: 32257153Free PMC Article

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