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Anti-Iglon5 antibody

MedGen UID:
1814144
•Concept ID:
C5558413
•
Laboratory or Test Result
Synonym: Anti-immunoglobulin-like cell adhesion molecule 5 antibody
 
HPO: HP:5000017

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against immunoglobulin-like cell adhesion molecule 5 (IgLON5). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-Iglon5 antibody

Professional guidelines

PubMed

Neuropathological spectrum of anti-IgLON5 disease and stages of brainstem tau pathology: updated neuropathological research criteria of the disease-related tauopathy.
Gelpi E, Reinecke R, Gaig C, Iranzo A, Sabater L, Molina-Porcel L, Aldecoa I, Endmayr V, Högl B, Schmutzhard E, Poewe W, Pfausler B, Popovic M, Pretnar-Oblak J, Leypoldt F, Matschke J, Glatzel M, Erro EM, Jerico I, Caballero MC, Zelaya MV, Mariotto S, Heidbreder A, Kalev O, Weis S, Macher S, Berger-Sieczkowski E, Ferrari J, Reisinger C, Klupp N, Tienari P, Rautila O, Niemelä M, Yilmazer-Hanke D, Guasp M, Bloem B, Van Gaalen J, Kusters B, Titulaer M, Fransen NL, Santamaria J, Dawson T, Holton JL, Ling H, Revesz T, Myllykangas L, Budka H, Kovacs GG, Lewerenz J, Dalmau J, Graus F, Koneczny I, Höftberger R
Acta Neuropathol 2024 Oct 14;148(1):53. doi: 10.1007/s00401-024-02805-y. PMID: 39400557Free PMC Article
Diagnostic criteria for autoimmune encephalitis: utility and pitfalls for antibody-negative disease.
Dalmau J, Graus F
Lancet Neurol 2023 Jun;22(6):529-540. doi: 10.1016/S1474-4422(23)00083-2. PMID: 37210100
Neuropathological criteria of anti-IgLON5-related tauopathy.
Gelpi E, Höftberger R, Graus F, Ling H, Holton JL, Dawson T, Popovic M, Pretnar-Oblak J, Högl B, Schmutzhard E, Poewe W, Ricken G, Santamaria J, Dalmau J, Budka H, Revesz T, Kovacs GG
Acta Neuropathol 2016 Oct;132(4):531-43. Epub 2016 Jun 29 doi: 10.1007/s00401-016-1591-8. PMID: 27358064Free PMC Article

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