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Uterine cervix mass

MedGen UID:
1841632
•Concept ID:
C5826734
•
Finding
HPO: HP:0034884

Definition

A swelling or enlargement localized to the cervis of the uterus. The word mass is usually used at an early stage of the diagnostic workup before the precise nature of the swelling has been determined. [from HPO]

Professional guidelines

PubMed

Current trends in the management and prevention of human papillomavirus (HPV) infection.
Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M, A Dimopoulos M, Gavriatopoulou M
J BUON 2020 May-Jun;25(3):1281-1285. PMID: 32862567
Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society.
Fontham ETH, Wolf AMD, Church TR, Etzioni R, Flowers CR, Herzig A, Guerra CE, Oeffinger KC, Shih YT, Walter LC, Kim JJ, Andrews KS, DeSantis CE, Fedewa SA, Manassaram-Baptiste D, Saslow D, Wender RC, Smith RA
CA Cancer J Clin 2020 Sep;70(5):321-346. Epub 2020 Jul 30 doi: 10.3322/caac.21628. PMID: 32729638
Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.
Koh WJ, Abu-Rustum NR, Bean S, Bradley K, Campos SM, Cho KR, Chon HS, Chu C, Clark R, Cohn D, Crispens MA, Damast S, Dorigo O, Eifel PJ, Fisher CM, Frederick P, Gaffney DK, Han E, Huh WK, Lurain JR, Mariani A, Mutch D, Nagel C, Nekhlyudov L, Fader AN, Remmenga SW, Reynolds RK, Tillmanns T, Ueda S, Wyse E, Yashar CM, McMillian NR, Scavone JL
J Natl Compr Canc Netw 2019 Jan;17(1):64-84. doi: 10.6004/jnccn.2019.0001. PMID: 30659131

Recent clinical studies

Etiology

Screening for women at risk of spontaneous preterm birth, including cervical incompetence.
Hui SYA
Best Pract Res Clin Obstet Gynaecol 2024 Sep;96:102519. Epub 2024 Jun 14 doi: 10.1016/j.bpobgyn.2024.102519. PMID: 38908916
Cervical Cancer Screening: Evolution of National Guidelines and Current Recommendations.
Khan MJ
Clin Obstet Gynecol 2023 Sep 1;66(3):470-477. Epub 2023 Jul 4 doi: 10.1097/GRF.0000000000000791. PMID: 37436937
Predictors of preterm birth.
Ville Y, Rozenberg P
Best Pract Res Clin Obstet Gynaecol 2018 Oct;52:23-32. Epub 2018 Jul 7 doi: 10.1016/j.bpobgyn.2018.05.002. PMID: 30309793
Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement.
US Preventive Services Task Force, Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW Jr, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB
JAMA 2018 Aug 21;320(7):674-686. doi: 10.1001/jama.2018.10897. PMID: 30140884
Cervical cancer.
Mera SL
Med Lab Sci 1991 Apr;48(2):155-60. PMID: 1658528

Diagnosis

Screening for women at risk of spontaneous preterm birth, including cervical incompetence.
Hui SYA
Best Pract Res Clin Obstet Gynaecol 2024 Sep;96:102519. Epub 2024 Jun 14 doi: 10.1016/j.bpobgyn.2024.102519. PMID: 38908916
Quality assurance in human papillomavirus testing for primary cervical screening.
Cuschieri K, Fellner MD, Arroyo Mühr LS, Padalko E, Correa RM, Dillner J, Gultekin M, Picconi MA
Int J Gynecol Cancer 2023 May 1;33(5):802-811. doi: 10.1136/ijgc-2022-004197. PMID: 36914171Free PMC Article
Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.
Koh WJ, Abu-Rustum NR, Bean S, Bradley K, Campos SM, Cho KR, Chon HS, Chu C, Clark R, Cohn D, Crispens MA, Damast S, Dorigo O, Eifel PJ, Fisher CM, Frederick P, Gaffney DK, Han E, Huh WK, Lurain JR, Mariani A, Mutch D, Nagel C, Nekhlyudov L, Fader AN, Remmenga SW, Reynolds RK, Tillmanns T, Ueda S, Wyse E, Yashar CM, McMillian NR, Scavone JL
J Natl Compr Canc Netw 2019 Jan;17(1):64-84. doi: 10.6004/jnccn.2019.0001. PMID: 30659131
Predictors of preterm birth.
Ville Y, Rozenberg P
Best Pract Res Clin Obstet Gynaecol 2018 Oct;52:23-32. Epub 2018 Jul 7 doi: 10.1016/j.bpobgyn.2018.05.002. PMID: 30309793
Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement.
US Preventive Services Task Force, Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW Jr, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW, Wong JB
JAMA 2018 Aug 21;320(7):674-686. doi: 10.1001/jama.2018.10897. PMID: 30140884

Therapy

Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.
Koh WJ, Abu-Rustum NR, Bean S, Bradley K, Campos SM, Cho KR, Chon HS, Chu C, Clark R, Cohn D, Crispens MA, Damast S, Dorigo O, Eifel PJ, Fisher CM, Frederick P, Gaffney DK, Han E, Huh WK, Lurain JR, Mariani A, Mutch D, Nagel C, Nekhlyudov L, Fader AN, Remmenga SW, Reynolds RK, Tillmanns T, Ueda S, Wyse E, Yashar CM, McMillian NR, Scavone JL
J Natl Compr Canc Netw 2019 Jan;17(1):64-84. doi: 10.6004/jnccn.2019.0001. PMID: 30659131
Predictors of preterm birth.
Ville Y, Rozenberg P
Best Pract Res Clin Obstet Gynaecol 2018 Oct;52:23-32. Epub 2018 Jul 7 doi: 10.1016/j.bpobgyn.2018.05.002. PMID: 30309793
The next steps in cervical screening.
Sankaranarayanan R, Qiao YL, Keita N
Womens Health (Lond) 2015 Mar;11(2):201-12. doi: 10.2217/whe.14.70. PMID: 25776294
Human papillomavirus and cervical cancer.
Crosbie EJ, Einstein MH, Franceschi S, Kitchener HC
Lancet 2013 Sep 7;382(9895):889-99. Epub 2013 Apr 23 doi: 10.1016/S0140-6736(13)60022-7. PMID: 23618600
Colposcopy.
Smith T
Nurs Stand 2000 Oct 11-17;15(4):47-52; quiz 54-5. doi: 10.7748/ns2000.10.15.4.47.c2930. PMID: 11971495

Prognosis

Nomogram-based prediction of cervical dysplasia persistence/recurrence.
Bogani G, Tagliabue E, Ferla S, Martinelli F, Ditto A, Chiappa V, Leone Roberti Maggiore U, Taverna F, Lombardo C, Lorusso D, Raspagliesi F
Eur J Cancer Prev 2019 Sep;28(5):435-440. doi: 10.1097/CEJ.0000000000000475. PMID: 30489353
Predictors of preterm birth.
Ville Y, Rozenberg P
Best Pract Res Clin Obstet Gynaecol 2018 Oct;52:23-32. Epub 2018 Jul 7 doi: 10.1016/j.bpobgyn.2018.05.002. PMID: 30309793
Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis.
Conde-Agudelo A, Romero R, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Erez O, Pacora P, Nicolaides KH
Am J Obstet Gynecol 2018 Jul;219(1):10-25. Epub 2018 Apr 7 doi: 10.1016/j.ajog.2018.03.028. PMID: 29630885Free PMC Article
Metastatic adenocarcinoma of the cervix presenting as a choroidal mass: A case report and review of literature of cervical metastases to the eye.
Nair AG, Asnani HT, Mehta VC, Mehta SV, Pathak RS
Indian J Ophthalmol 2015 Aug;63(8):674-8. doi: 10.4103/0301-4738.169792. PMID: 26576527Free PMC Article
Reproductive health care after transplantation.
Krajewski C, Sucato G
Best Pract Res Clin Obstet Gynaecol 2014 Nov;28(8):1222-34. doi: 10.1016/j.bpobgyn.2014.09.002. PMID: 25450188

Clinical prediction guides

Reproducible and clinically translatable deep neural networks for cervical screening.
Ahmed SR, Befano B, Lemay A, Egemen D, Rodriguez AC, Angara S, Desai K, Jeronimo J, Antani S, Campos N, Inturrisi F, Perkins R, Kreimer A, Wentzensen N, Herrero R, Del Pino M, Quint W, de Sanjose S, Schiffman M, Kalpathy-Cramer J
Sci Rep 2023 Dec 8;13(1):21772. doi: 10.1038/s41598-023-48721-1. PMID: 38066031Free PMC Article
Current trends in the management and prevention of human papillomavirus (HPV) infection.
Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M, A Dimopoulos M, Gavriatopoulou M
J BUON 2020 May-Jun;25(3):1281-1285. PMID: 32862567
Nomogram-based prediction of cervical dysplasia persistence/recurrence.
Bogani G, Tagliabue E, Ferla S, Martinelli F, Ditto A, Chiappa V, Leone Roberti Maggiore U, Taverna F, Lombardo C, Lorusso D, Raspagliesi F
Eur J Cancer Prev 2019 Sep;28(5):435-440. doi: 10.1097/CEJ.0000000000000475. PMID: 30489353
Predictors of preterm birth.
Ville Y, Rozenberg P
Best Pract Res Clin Obstet Gynaecol 2018 Oct;52:23-32. Epub 2018 Jul 7 doi: 10.1016/j.bpobgyn.2018.05.002. PMID: 30309793
Adenocarcinoma in situ and early invasive adenocarcinoma of the uterine cervix.
Shipman SD, Bristow RE
Curr Opin Oncol 2001 Sep;13(5):394-8. doi: 10.1097/00001622-200109000-00014. PMID: 11555719

Recent systematic reviews

National Data Analysis and Systematic Review for Human Resources for Cervical Cancer Screening in Japan.
Hamashima C, Sasaki S, Hosono S, Hoshi K, Katayama T, Terasawa T
Asian Pac J Cancer Prev 2021 Jun 1;22(6):1695-1702. doi: 10.31557/APJCP.2021.22.6.1695. PMID: 34181323Free PMC Article
A systematic review and meta-analysis of sarcopenia as a prognostic factor in gynecological malignancy.
Allanson ER, Peng Y, Choi A, Hayes S, Janda M, Obermair A
Int J Gynecol Cancer 2020 Nov;30(11):1791-1797. Epub 2020 Aug 2 doi: 10.1136/ijgc-2020-001678. PMID: 32747410
Evaluating the implementation of cervical cancer screening programs in low-resource settings globally: a systematized review.
Dykens JA, Smith JS, Demment M, Marshall E, Schuh T, Peters K, Irwin T, McIntosh S, Sy A, Dye T
Cancer Causes Control 2020 May;31(5):417-429. Epub 2020 Mar 17 doi: 10.1007/s10552-020-01290-4. PMID: 32185604Free PMC Article
Guidelines for Cervical Cancer Screening in Immunosuppressed Women Without HIV Infection.
Moscicki AB, Flowers L, Huchko MJ, Long ME, MacLaughlin KL, Murphy J, Spiryda LB, Gold MA
J Low Genit Tract Dis 2019 Apr;23(2):87-101. doi: 10.1097/LGT.0000000000000468. PMID: 30907775
Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis.
Conde-Agudelo A, Romero R, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Erez O, Pacora P, Nicolaides KH
Am J Obstet Gynecol 2018 Jul;219(1):10-25. Epub 2018 Apr 7 doi: 10.1016/j.ajog.2018.03.028. PMID: 29630885Free PMC Article

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