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Demonstration of Leishmania in tissue

MedGen UID:
1863805
•Concept ID:
C5937073
•
Laboratory or Test Result
HPO: HP:6000255

Definition

Presence of Leishmania, a parasitic protozoan, in a tissue specimen. Leishmania is responsible for leishmaniasis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDemonstration of Leishmania in tissue

Professional guidelines

PubMed

Efficacy of malachite green mediated photodynamic therapy on treatment of Cutaneous Leishmaniasis: In vitro study.
Ozlem-Caliskan S, Ilikci-Sagkan R, Karakas H, Sever S, Yildirim C, Balikci M, Ertabaklar H
Photodiagnosis Photodyn Ther 2022 Dec;40:103111. Epub 2022 Sep 6 doi: 10.1016/j.pdpdt.2022.103111. PMID: 36075521
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis.
Tear WF, Bag S, Diaz-Gonzalez R, Ceballos-Pérez G, Rojas-Barros DI, Cordon-Obras C, Pérez-Moreno G, García-Hernández R, Martinez-Martinez MS, Ruiz-Perez LM, Gamarro F, Gonzalez Pacanowska D, Caffrey CR, Ferrins L, Manzano P, Navarro M, Pollastri MP
J Med Chem 2020 Jan 23;63(2):756-783. Epub 2020 Jan 8 doi: 10.1021/acs.jmedchem.9b01741. PMID: 31846577Free PMC Article
Efficacy of lapachol on treatment of cutaneous and visceral leishmaniasis.
Araújo IAC, de Paula RC, Alves CL, Faria KF, Oliveira MM, Mendes GG, Dias EMFA, Ribeiro RR, Oliveira AB, Silva SMD
Exp Parasitol 2019 Apr;199:67-73. Epub 2019 Feb 21 doi: 10.1016/j.exppara.2019.02.013. PMID: 30797783

Recent systematic reviews

Accuracy of the direct agglutination test for diagnosis of visceral leishmaniasis: a systematic review and meta-analysis.
Roberts T, Keddie SH, Rattanavong S, Gomez SR, Bradley J, Keogh RH, Bärenbold O, Falconer J, Mens PF, Hopkins H, Ashley EA
BMC Infect Dis 2023 Nov 9;23(1):782. doi: 10.1186/s12879-023-08772-1. PMID: 37946107Free PMC Article

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