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Urethra squamous cell carcinoma

MedGen UID:
234975
Concept ID:
C1336890
Neoplastic Process
Synonyms: Epidermoid Carcinoma of the Urethra; epidermoid carcinoma of the urethra; Epidermoid Carcinoma of Urethra; epidermoid carcinoma of urethra; Squamous Cell Carcinoma of the Urethra; squamous cell carcinoma of the urethra; Squamous Cell Carcinoma of Urethra; squamous cell carcinoma of urethra; Urethra Epidermoid Carcinoma; urethra epidermoid carcinoma; Urethra Squamous Cell Carcinoma; urethra squamous cell carcinoma; Urethral Epidermoid Carcinoma; urethral epidermoid carcinoma; urethral squamous cell cancer; Urethral Squamous Cell Carcinoma; urethral squamous cell carcinoma; USCC
 
Monarch Initiative: MONDO:0002764

Definition

A well differentiated, moderately differentiated, or poorly differentiated squamous cell carcinoma that arises from the male or female urethra. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrethra squamous cell carcinoma

Professional guidelines

PubMed

Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949
Eng TY, Chen TW, Patel AJ, Vincent JN, Ha CS
Am J Clin Oncol 2018 Sep;41(9):905-908. doi: 10.1097/COC.0000000000000391. PMID: 28537991
Zargar-Shoshtari K, Sexton WJ, Poch MA
Urol Clin North Am 2016 Nov;43(4):515-521. doi: 10.1016/j.ucl.2016.06.012. PMID: 27717437

Recent clinical studies

Etiology

Castiglione F, Alnajjar HM, Christodoulidou M, Albersen M, Parnham A, Freeman A, Jameson C, Mitra A, Nigam R, Malone P, Muneer A; Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
Eur Urol Focus 2021 Jan;7(1):163-169. Epub 2019 Mar 7 doi: 10.1016/j.euf.2019.02.016. PMID: 30853605
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Torbrand C, Håkansson U, Ehrnström R, Liedberg F
Clin Genitourin Cancer 2017 Dec;15(6):e1131-e1135. Epub 2017 Jul 14 doi: 10.1016/j.clgc.2017.07.006. PMID: 28784424
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077
Peterson DT, Dockerty MB, Utz DC, Symmonds RE
J Urol 1973 Jul;110(1):72-5. doi: 10.1016/s0022-5347(17)60119-8. PMID: 4713364

Diagnosis

Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Torbrand C, Håkansson U, Ehrnström R, Liedberg F
Clin Genitourin Cancer 2017 Dec;15(6):e1131-e1135. Epub 2017 Jul 14 doi: 10.1016/j.clgc.2017.07.006. PMID: 28784424
Zargar-Shoshtari K, Sexton WJ, Poch MA
Urol Clin North Am 2016 Nov;43(4):515-521. doi: 10.1016/j.ucl.2016.06.012. PMID: 27717437
Wong JT, Wasserman NF, Padurean AM
Radiographics 2004 May-Jun;24(3):855-60. doi: 10.1148/rg.243035153. PMID: 15143234
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077

Therapy

Baird BA, Lyon TD, Wu K, Anderson A, Broderick GA
Can J Urol 2022 Apr;29(2):11119-11122. PMID: 35429432
Castiglione F, Alnajjar HM, Christodoulidou M, Albersen M, Parnham A, Freeman A, Jameson C, Mitra A, Nigam R, Malone P, Muneer A; Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
Eur Urol Focus 2021 Jan;7(1):163-169. Epub 2019 Mar 7 doi: 10.1016/j.euf.2019.02.016. PMID: 30853605
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077
Denewer A, Kotb S, Hussein O, El-Maadawy M
World J Surg 1999 Jun;23(6):608-11. doi: 10.1007/pl00012355. PMID: 10227932
Grabstald H, Hilaris B, Henschke U, Whitmore WF Jr
JAMA 1966 Sep 12;197(11):835-42. PMID: 5952770

Prognosis

Baird BA, Lyon TD, Wu K, Anderson A, Broderick GA
Can J Urol 2022 Apr;29(2):11119-11122. PMID: 35429432
Gadducci A, Aletti GD
Gynecol Oncol 2020 Jul;158(1):208-217. Epub 2020 May 25 doi: 10.1016/j.ygyno.2020.05.021. PMID: 32460996
Torbrand C, Håkansson U, Ehrnström R, Liedberg F
Clin Genitourin Cancer 2017 Dec;15(6):e1131-e1135. Epub 2017 Jul 14 doi: 10.1016/j.clgc.2017.07.006. PMID: 28784424
Salom EM, Penalver M
Curr Treat Options Oncol 2002 Apr;3(2):143-53. doi: 10.1007/s11864-002-0060-x. PMID: 12057077
Grabstald H, Hilaris B, Henschke U, Whitmore WF Jr
JAMA 1966 Sep 12;197(11):835-42. PMID: 5952770

Clinical prediction guides

Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949
Pleunis N, Leermakers MEJ, van der Wurff AA, Klinkhamer PJJM, Ezendam NPM, Boll D, de Hullu JA, Pijnenborg JMA
Eur J Surg Oncol 2018 Oct;44(10):1555-1561. Epub 2018 Jun 6 doi: 10.1016/j.ejso.2018.05.031. PMID: 29934053
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Yasuda M, Tamura A, Shimizu A, Takahashi A, Ishikawa O
J Dermatol 2005 Mar;32(3):210-3. doi: 10.1111/j.1346-8138.2005.tb00747.x. PMID: 15863869
Ampil FL
Obstet Gynecol 1985 Dec;66(6):799-804. PMID: 3934611

Recent systematic reviews

Andrews AR, Kakadekar A, Schmidt RL, Murugan P, Greene DN
Arch Pathol Lab Med 2022 Jan 2;146(2):252-261. doi: 10.5858/arpa.2020-0704-RA. PMID: 33983412
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949

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