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Trachea sarcoma

MedGen UID:
237016
•Concept ID:
C1336774
•
Neoplastic Process
Synonyms: Sarcoma of the Trachea; sarcoma of the trachea; Sarcoma of Trachea; sarcoma of trachea; Trachea Sarcoma; trachea sarcoma; Tracheal Sarcoma; tracheal sarcoma
 
Monarch Initiative: MONDO:0001418

Definition

A rare malignant soft tissue neoplasm that arises from the trachea. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTrachea sarcoma

Professional guidelines

PubMed

Treatment outcomes of patients with primary tracheal tumors - analysis of a large retrospective series.
Piórek A, Płużański A, Knetki-Wróblewska M, Winiarczyk K, Tabor S, Teterycz P, Kowalski DM, Krzakowski M
BMC Cancer 2024 Jun 5;24(1):686. doi: 10.1186/s12885-024-12450-z. PMID: 38840114Free PMC Article
Radiation treatment for adult rare cancers: Oldest and newest indication.
Fiorentino A, Gregucci F, Desideri I, Fiore M, Marino L, Errico A, Di Rito A, Borghetti P, Franco P, Greto D, Donato V
Crit Rev Oncol Hematol 2021 Mar;159:103228. Epub 2021 Jan 27 doi: 10.1016/j.critrevonc.2021.103228. PMID: 33508447
Clinical manifestation and management of primary malignant tumors of the cervical trachea.
Li Y, Peng A, Yang X, Xiao Z, Wu W, Wang Q
Eur Arch Otorhinolaryngol 2014 Feb;271(2):225-35. Epub 2013 Mar 20 doi: 10.1007/s00405-013-2429-9. PMID: 23512430

Recent clinical studies

Etiology

Radiation treatment for adult rare cancers: Oldest and newest indication.
Fiorentino A, Gregucci F, Desideri I, Fiore M, Marino L, Errico A, Di Rito A, Borghetti P, Franco P, Greto D, Donato V
Crit Rev Oncol Hematol 2021 Mar;159:103228. Epub 2021 Jan 27 doi: 10.1016/j.critrevonc.2021.103228. PMID: 33508447
Hybrid bronchoscopic and surgical resection of endotracheal angiomatoid fibrous histiocytoma.
Bouma W, Koning KJ, Suurmeijer AJH, Slebos DJ, Mariani MA, Klinkenberg TJ
J Cardiothorac Surg 2019 Feb 28;14(1):48. doi: 10.1186/s13019-019-0861-7. PMID: 30819218Free PMC Article
Primary Thyroid Sarcoma: A Systematic Review.
Surov A, Gottschling S, Wienke A, Meyer HJ, Spielmann RP, Dralle H
Anticancer Res 2015 Oct;35(10):5185-91. PMID: 26408676
Giant Cervico-mediastinal Well-differentiated Liposarcoma.
Rena O, Davoli F, Pia F, Roncon A, Papalia E, Casadio C
Heart Lung Circ 2015 Jul;24(7):e112-4. Epub 2015 Mar 2 doi: 10.1016/j.hlc.2015.02.015. PMID: 25837020
Tracheal chondrosarcoma: a case report.
Farrell ML, Gluckman JL, Biddinger P
Head Neck 1998 Sep;20(6):568-72. doi: 10.1002/(sici)1097-0347(199809)20:6<568::aid-hed13>3.0.co;2-d. PMID: 9702546

Diagnosis

Tracheal Chondrosarcoma-A Novel Presentation of Lynch Syndrome.
Bhat AM, Gerndt S, Sandhu A, Helfand AM, Jiwani R, Low GMI
JAMA Otolaryngol Head Neck Surg 2024 Feb 1;150(2):183-184. doi: 10.1001/jamaoto.2023.3908. PMID: 38095912
Tracheobronchial Myeloid Sarcoma (Chloroma).
Psathakis K, Dendrinou GE, Messini I, Tsirkinidis P, Frangia-Tsivou K
J Bronchology Interv Pulmonol 2020 Oct;27(4):297-300. doi: 10.1097/LBR.0000000000000693. PMID: 32604321
Tracheal chondrosarcoma and surgical management.
Khan FW, Zahid I, Moeen S, Hasan SB
Asian Cardiovasc Thorac Ann 2019 Jan;27(1):52-54. Epub 2018 Jun 3 doi: 10.1177/0218492318778484. PMID: 29860896
Tracheal and airway neoplasms.
Wu CC, Shepard JA
Semin Roentgenol 2013 Oct;48(4):354-64. doi: 10.1053/j.ro.2013.03.018. PMID: 24034267
Tracheal chondrosarcoma.
Umezu H, Tamura M, Kobayashi S, Sawabata N, Honma K, Miyoshi S
Gen Thorac Cardiovasc Surg 2008 Apr;56(4):199-202. Epub 2008 Apr 10 doi: 10.1007/s11748-007-0218-3. PMID: 18401685

Therapy

Primary Thyroid Angiosarcoma with Tracheal Invasion.
Yoon Moon S, Su Park H, Young Woo J, Kyun Choi J, Oh H, Up Kim K, Soo Rho Y, Chung EJ, Cho S, Ko Y, Young Park S, Mo EK, Bum Park Y
Intern Med 2016;55(9):1165-9. Epub 2016 May 1 doi: 10.2169/internalmedicine.55.5447. PMID: 27150873
Mediastinal sarcoma with deviated tracheal anatomy.
Chandra P, Schmidt RM, Madan P, Topkara VK
J Thorac Oncol 2008 Jan;3(1):82-3. doi: 10.1097/JTO.0b013e31815ba2b5. PMID: 18166845
Kaposi's sarcoma in a patient with severe relapsing polychondritis.
Manghani MK, Andrews J, Higgens CS
Rheumatol Int 2004 Sep;24(5):309-11. Epub 2003 Dec 5 doi: 10.1007/s00296-003-0410-4. PMID: 14658005
Bronchial Kaposi's sarcoma after single lung transplantation.
Sleiman C, Mal H, Roué C, Groussard O, Baldeyrou P, Olivier P, Fournier M, Pariente R
Eur Respir J 1997 May;10(5):1181-3. doi: 10.1183/09031936.97.10051181. PMID: 9163665
Computed tomography of the chest in infants and children: techniques and mediastinal evaluation.
Kirks DR, Korobkin M
Radiol Clin North Am 1981 Sep;19(3):409-19. PMID: 7029611

Prognosis

Tracheobronchial Myeloid Sarcoma (Chloroma).
Psathakis K, Dendrinou GE, Messini I, Tsirkinidis P, Frangia-Tsivou K
J Bronchology Interv Pulmonol 2020 Oct;27(4):297-300. doi: 10.1097/LBR.0000000000000693. PMID: 32604321
Extended surgery using anterior mediastinal tracheostomy for recurrent mediastinal liposarcoma.
Takenaka M, Ichiki Y, Taira A, Tanaka F
Eur J Cardiothorac Surg 2018 Aug 1;54(2):397-399. doi: 10.1093/ejcts/ezy021. PMID: 29415198
Primary Thyroid Angiosarcoma with Tracheal Invasion.
Yoon Moon S, Su Park H, Young Woo J, Kyun Choi J, Oh H, Up Kim K, Soo Rho Y, Chung EJ, Cho S, Ko Y, Young Park S, Mo EK, Bum Park Y
Intern Med 2016;55(9):1165-9. Epub 2016 May 1 doi: 10.2169/internalmedicine.55.5447. PMID: 27150873
Tracheal chondrosarcoma: a case report.
Farrell ML, Gluckman JL, Biddinger P
Head Neck 1998 Sep;20(6):568-72. doi: 10.1002/(sici)1097-0347(199809)20:6<568::aid-hed13>3.0.co;2-d. PMID: 9702546
The laryngeal subglottis.
Bryce DP
J Laryngol Otol 1975 Jul;89(7):667-85. doi: 10.1017/s0022215100080890. PMID: 1176819

Clinical prediction guides

Expanded indications for auto-lung transplant technique.
Nakajima D, Ohsumi A, Hamaji M, Chen-Yoshikawa TF, Date H
Gen Thorac Cardiovasc Surg 2020 Aug;68(8):828-832. Epub 2020 Jan 14 doi: 10.1007/s11748-020-01289-3. PMID: 31939102
Primary mediastinal liposarcoma, with 6 years of follow-up to autopsy, revealed histopathological features of primary and metastatic lesions.
Konno S, Oizumi S, Shinagawa N, Kikuchi E, Konishi J, Ito K, Hizawa N, Takiyama A, Tanaka S, Nishimura M
Intern Med 2010;49(8):771-5. Epub 2010 Apr 15 doi: 10.2169/internalmedicine.49.2974. PMID: 20424369
Bronchial Kaposi's sarcoma after single lung transplantation.
Sleiman C, Mal H, Roué C, Groussard O, Baldeyrou P, Olivier P, Fournier M, Pariente R
Eur Respir J 1997 May;10(5):1181-3. doi: 10.1183/09031936.97.10051181. PMID: 9163665
Sarcomatoid neoplasms of the respiratory tract.
Nappi O, Wick MR
Semin Diagn Pathol 1993 May;10(2):137-47. PMID: 8367623
Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.
Yoshimura K, Rosenfeld MA, Nakamura H, Scherer EM, Pavirani A, Lecocq JP, Crystal RG
Nucleic Acids Res 1992 Jun 25;20(12):3233-40. doi: 10.1093/nar/20.12.3233. PMID: 1377820Free PMC Article

Recent systematic reviews

Tracheal chondrosarcoma: A case report, systematic review, and pooled analysis.
Heuermann M, Bekker S, Czeczok T, Gregory S, Sharma A
Cancer Rep (Hoboken) 2022 Jul;5(7):e1537. Epub 2021 Sep 2 doi: 10.1002/cnr2.1537. PMID: 34476908Free PMC Article
Demography, patterns of care and survival outcomes in patients with malignant tumors of trachea: A systematic review and individual patient data analysis of 733 patients.
Mallick S, Benson R, Giridhar P, Rajan Singh A, Rath GK
Lung Cancer 2019 Jun;132:87-93. Epub 2019 Apr 10 doi: 10.1016/j.lungcan.2019.04.017. PMID: 31097099
Primary Thyroid Sarcoma: A Systematic Review.
Surov A, Gottschling S, Wienke A, Meyer HJ, Spielmann RP, Dralle H
Anticancer Res 2015 Oct;35(10):5185-91. PMID: 26408676

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