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Thyroid gland squamous cell carcinoma

MedGen UID:
328050
•Concept ID:
C1710177
•
Neoplastic Process
Synonyms: squamous cell thyroid gland carcinoma; Thyroid Gland Anaplastic Carcinoma, Squamous Cell Carcinoma Pattern; Thyroid Gland Squamous Cell Carcinoma; thyroid gland squamous cell carcinoma
 
Monarch Initiative: MONDO:0006467

Definition

Thyroid gland anaplastic carcinoma with focal or complete squamous differentiation. Primary thyroid gland squamous cell carcinomas have similar poor overall survival rates as compared to conventional anaplastic thyroid gland carcinomas and are now considered a subtype of the latter. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThyroid gland squamous cell carcinoma

Professional guidelines

PubMed

Primary Total Laryngectomy for Endolaryngeal cT3-4M0 Squamous Cell Carcinoma: A STROBE Analysis.
Laccourreye O, Garcia D, Haroun F, Nguyen DH, Giraud P, Mirghani H
Laryngoscope 2024 May;134(5):2288-2294. Epub 2023 Nov 3 doi: 10.1002/lary.31129. PMID: 37921374
Clinical Practice Guideline: Evaluation of the Neck Mass in Adults.
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Squamous cell carcinoma of the thyroid gland: primary or secondary disease?
Syed MI, Stewart M, Syed S, Dahill S, Adams C, McLellan DR, Clark LJ
J Laryngol Otol 2011 Jan;125(1):3-9. Epub 2010 Oct 18 doi: 10.1017/S0022215110002070. PMID: 20950510

Recent clinical studies

Etiology

Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
Thyroid gland invasion in total laryngectomy: A systematic review and meta-analysis.
Xie J, Wu P, Liu H, Zhang S, Lu Z
Int J Surg 2022 Mar;99:106262. Epub 2022 Feb 13 doi: 10.1016/j.ijsu.2022.106262. PMID: 35172203
Vitamin D Receptor Polymorphisms and Cancer.
Gnagnarella P, Raimondi S, Aristarco V, Johansson HA, Bellerba F, Corso F, Gandini S
Adv Exp Med Biol 2020;1268:53-114. doi: 10.1007/978-3-030-46227-7_4. PMID: 32918214
Metastasis of squamous cell carcinoma of the head and neck to the thyroid: a single institution's experience with a review of relevant publications.
Vatsyayan A, Mandlik D, Patel P, Patel P, Sharma N, Joshipura A, Patel M, Odedra P, Dubbal JC, Shah DS, Kanhere SA, Sanghvi KJ, Patel K
Br J Oral Maxillofac Surg 2019 Sep;57(7):609-615. Epub 2019 Jun 10 doi: 10.1016/j.bjoms.2019.05.012. PMID: 31196573
Clinical Practice Guideline: Evaluation of the Neck Mass in Adults.
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406

Diagnosis

Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
Metastatic cervical carcinoma to the thyroid gland: A rare diagnosis.
Varlı B, Taşkın S, Ortaç F
Taiwan J Obstet Gynecol 2019 Mar;58(2):298-299. doi: 10.1016/j.tjog.2019.01.024. PMID: 30910158
Clinical Practice Guideline: Evaluation of the Neck Mass in Adults.
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Intrathyroidal multiloculated proliferating thymic cyst.
Chaudhari J, Fernandez G, Naik L, Pirosha A
Endocr Pathol 2015 Mar;26(1):45-7. doi: 10.1007/s12022-015-9355-x. PMID: 25600589
Thyroglossal duct carcinoma.
Motamed M, McGlashan JA
Curr Opin Otolaryngol Head Neck Surg 2004 Apr;12(2):106-9. doi: 10.1097/00020840-200404000-00009. PMID: 15167046

Therapy

Emerging tyrosine kinase inhibitors for head and neck cancer.
Long Z, Grandis JR, Johnson DE
Expert Opin Emerg Drugs 2022 Sep;27(3):333-344. Epub 2022 Sep 21 doi: 10.1080/14728214.2022.2125954. PMID: 36131561Free PMC Article
Thyroid gland invasion in total laryngectomy: A systematic review and meta-analysis.
Xie J, Wu P, Liu H, Zhang S, Lu Z
Int J Surg 2022 Mar;99:106262. Epub 2022 Feb 13 doi: 10.1016/j.ijsu.2022.106262. PMID: 35172203
Diffusion-weighted and PET/MR Imaging after Radiation Therapy for Malignant Head and Neck Tumors.
Varoquaux A, Rager O, Dulguerov P, Burkhardt K, Ailianou A, Becker M
Radiographics 2015 Sep-Oct;35(5):1502-27. Epub 2015 Aug 7 doi: 10.1148/rg.2015140029. PMID: 26252192
Late sequelae of radiation therapy in cancer of the head and neck with particular reference to the nasopharynx.
Ballantyne AJ
Am J Surg 1975 Oct;130(4):433-6. doi: 10.1016/0002-9610(75)90479-1. PMID: 1101723
THE NODULAR THYROID GLAND AND CANCER. A PRACTICAL APPROACH TO THE PROBLEM.
VEITH FJ, BROOKS JR, GRIGSBY WP, SELENKOW HA
N Engl J Med 1964 Feb 27;270:431-6. doi: 10.1056/NEJM196402272700901. PMID: 14163220

Prognosis

The rare combination of low-grade thyroid-like nasopharyngeal papillary adenocarcinoma and squamous cell carcinoma: a case report and literature review.
Toyran T, Inceman M, Erdogan K, Kücükosmanoglu A, Ekici NY, Ugu AH
Pol J Pathol 2022;73(4):359-363. doi: 10.5114/pjp.2022.125569. PMID: 36946273
Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
Clinical Practice Guideline: Evaluation of the Neck Mass in Adults.
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Annexin A4 and cancer.
Wei B, Guo C, Liu S, Sun MZ
Clin Chim Acta 2015 Jul 20;447:72-8. Epub 2015 Jun 3 doi: 10.1016/j.cca.2015.05.016. PMID: 26048190
Thyroglossal duct carcinoma.
Motamed M, McGlashan JA
Curr Opin Otolaryngol Head Neck Surg 2004 Apr;12(2):106-9. doi: 10.1097/00020840-200404000-00009. PMID: 15167046

Clinical prediction guides

The rare combination of low-grade thyroid-like nasopharyngeal papillary adenocarcinoma and squamous cell carcinoma: a case report and literature review.
Toyran T, Inceman M, Erdogan K, Kücükosmanoglu A, Ekici NY, Ugu AH
Pol J Pathol 2022;73(4):359-363. doi: 10.5114/pjp.2022.125569. PMID: 36946273
Thyroid gland invasion in total laryngectomy: A systematic review and meta-analysis.
Xie J, Wu P, Liu H, Zhang S, Lu Z
Int J Surg 2022 Mar;99:106262. Epub 2022 Feb 13 doi: 10.1016/j.ijsu.2022.106262. PMID: 35172203
Applications of Computational Pathology in Head and Neck Cytopathology.
Lollie TK, Krane JF
Acta Cytol 2021;65(4):330-334. Epub 2021 Feb 23 doi: 10.1159/000513286. PMID: 33621977
Thyroid gland invasion in advanced squamous cell carcinoma of the larynx and hypopharynx.
Mangussi-Gomes J, Danelon-Leonhardt F, Moussalem GF, Ahumada NG, Oliveira CL, Hojaij FC
Braz J Otorhinolaryngol 2017 May-Jun;83(3):269-275. Epub 2016 May 7 doi: 10.1016/j.bjorl.2016.03.019. PMID: 27209377Free PMC Article
Orbital syndromes.
Bhatti MT
Semin Neurol 2007 Jul;27(3):269-87. doi: 10.1055/s-2007-979685. PMID: 17577868

Recent systematic reviews

Thyroid gland invasion in total laryngectomy: A systematic review and meta-analysis.
Xie J, Wu P, Liu H, Zhang S, Lu Z
Int J Surg 2022 Mar;99:106262. Epub 2022 Feb 13 doi: 10.1016/j.ijsu.2022.106262. PMID: 35172203
Vitamin D Receptor Polymorphisms and Cancer.
Gnagnarella P, Raimondi S, Aristarco V, Johansson HA, Bellerba F, Corso F, Gandini S
Adv Exp Med Biol 2020;1268:53-114. doi: 10.1007/978-3-030-46227-7_4. PMID: 32918214
Cervical esophageal cancer: a gap in cancer knowledge.
Hoeben A, Polak J, Van De Voorde L, Hoebers F, Grabsch HI, de Vos-Geelen J
Ann Oncol 2016 Sep;27(9):1664-74. Epub 2016 Apr 26 doi: 10.1093/annonc/mdw183. PMID: 27117535
Primary squamous cell carcinomas in the thyroid gland: an individual participant data meta-analysis.
Cho JK, Woo SH, Park J, Kim MJ, Jeong HS
Cancer Med 2014 Oct;3(5):1396-403. Epub 2014 Jul 4 doi: 10.1002/cam4.287. PMID: 24995699Free PMC Article
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197

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