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Choroid plexus neoplasm

MedGen UID:
38980
•Concept ID:
C0085138
•
Neoplastic Process
Synonyms: Choroid Plexus Neoplasm; Choroid Plexus Neoplasms; Choroid Plexus Tumor; Choroid Plexus Tumors; Neoplasm, Choroid Plexus; Neoplasms, Choroid Plexus
SNOMED CT: Tumor of choroid plexus (254942002)
 
Monarch Initiative: MONDO:0016717
Orphanet: ORPHA251896

Definition

An intraventricular neoplasm that originates from the choroid plexus. The vast majority of choroid plexus neoplasms originate from the epithelial layer and include the choroid plexus papilloma, atypical choroid plexus papilloma, and choroid plexus carcinoma. [from NCI]

Professional guidelines

PubMed

Triple intraventricular chemotherapy for treatment of relapsed choroid plexus carcinoma.
Lau G, Drummond J, Zhukova N, Wood P, Janson L
Pediatr Blood Cancer 2021 Sep;68(9):e29094. Epub 2021 May 18 doi: 10.1002/pbc.29094. PMID: 34003555
Synaptophysin in choroid plexus epithelial cells: no useful aid in differential diagnosis.
Paulus W, Brandner S
J Neuropathol Exp Neurol 1999 Oct;58(10):1111-2. doi: 10.1097/00005072-199910000-00010. PMID: 10515234
The role of radiotherapy in the management of choroid plexus neoplasms.
Palazzi M, Di Marco A, Campostrini F, Grandinetti A, Bontempini L
Tumori 1989 Oct 31;75(5):463-9. doi: 10.1177/030089168907500512. PMID: 2690434

Recent clinical studies

Diagnosis

Choroid Plexus Pathophysiology.
Courtney Y, Hochstetler A, Lehtinen MK
Annu Rev Pathol 2025 Jan;20(1):193-220. Epub 2025 Jan 2 doi: 10.1146/annurev-pathmechdis-051222-114051. PMID: 39383438
Intraventricular metastasis from carcinoma breast masquerading as choroid plexus neoplasm: A case report.
Dhamecha M, Sharma A, Kamboj M, Pahwa S, Pasricha S
Indian J Pathol Microbiol 2022 Jul-Sep;65(3):719-721. doi: 10.4103/ijpm.ijpm_92_21. PMID: 35900513
Tubular (acinar) transformation of the choroid plexus epithelium.
Shintaku M
Brain Tumor Pathol 2002;19(1):31-4. doi: 10.1007/BF02482453. PMID: 12455886
Ultrasonic diagnosis of a choroid plexus neoplasm in a child.
Reddy PS, Wild SR, Hendry GM
Br J Radiol 1984 Apr;57(676):342-4. doi: 10.1259/0007-1285-57-676-342. PMID: 6704671

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