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Enlarged uterus

MedGen UID:: 452126
•Concept ID:: C0151994
•: Finding

Synonyms:	Enlarged Uterus; Large uterus; Uterine enlargement
SNOMED CT:	Enlarged uterus (198319004); Uterine enlargement (198319004); Large uterus (198319004)

HPO:	HP:0100878

Definition

An increase in the overall dimensions or volume of the uterus compared to normal. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVEnlarged uterus

Abnormality of the genital system
- Abnormal reproductive system morphology
  - Abnormality of the female genitalia
    - Abnormal morphology of female internal genitalia
      - Congenital uterine anomaly
        Abnormal uterus morphology
        Enlarged uterus

Professional guidelines

PubMed

Long-term efficacy and safety of levonorgestrel releasing intrauterine system in the treatment of adenomyosis: evidence mapping.

Shi J, Gu Z, Wu Y, Li X, Zhang J, Zhang C, Yan H, Dai Y, Leng J
Arch Gynecol Obstet 2024 Jul;310(1):55-67. Epub 2024 Jun 5 doi: 10.1007/s00404-024-07546-7. PMID: 38836931

Diagnosis and initial management of dysmenorrhea.

Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505

Diagnosis, treatment and need for hysterectomy in management of postcaesarean section vesicouterine fistula.

Ali-El-Dein B, El-Tabey N, El-Hefnawy A, Osman Y, Soliman S, Shaaban AA
Scand J Urol 2014 Oct;48(5):460-5. Epub 2014 Apr 3 doi: 10.3109/21681805.2014.903511. PMID: 24694181

See all (13)

Recent clinical studies

Etiology

Recurrence of Uterine Fibroids After Conservative Surgery or Radiological Procedures: a Narrative Review.

Capezzuoli T, Aslan B, Vannuccini S, Orlandi G, La Torre F, Sorbi F, Fambrini M, Petraglia F
Reprod Sci 2024 May;31(5):1171-1178. Epub 2023 Dec 18 doi: 10.1007/s43032-023-01418-2. PMID: 38110820

Ovarian vein thrombophlebitis related to large uterine myoma.

Haynes MC, Lu BY, Winkel AF
Obstet Gynecol 2014 Feb;123(2 Pt 2 Suppl 2):450-453. doi: 10.1097/AOG.0000000000000091. PMID: 24413242

Reproductive hormones and stress urinary incontinence in pregnancy.

Kristiansson P, Samuelsson E, von Schoultz B, Svärdsudd K
Acta Obstet Gynecol Scand 2001 Dec;80(12):1125-30. doi: 10.1034/j.1600-0412.2001.801209.x. PMID: 11846710

Abdominopelvic MR imaging in the nonobstetric evaluation of pregnant patients.

Forstner R, Kalbhen CL, Filly RA, Hricak H
AJR Am J Roentgenol 1996 May;166(5):1139-44. doi: 10.2214/ajr.166.5.8615258. PMID: 8615258

Histopathological findings in 226 women with post-menopausal uterine bleeding.

Lidor A, Ismajovich B, Confino E, David MP
Acta Obstet Gynecol Scand 1986;65(1):41-3. doi: 10.3109/00016348609158227. PMID: 3716779

See all (104)

Diagnosis

Clinical practice. Uterine fibroids.

Stewart EA
N Engl J Med 2015 Apr 23;372(17):1646-55. doi: 10.1056/NEJMcp1411029. PMID: 25901428

Diagnosis and initial management of dysmenorrhea.

Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505

MR imaging of uterine adenosarcoma: case report and literature review.

Yoshizako T, Wada A, Kitagaki H, Ishikawa N, Miyazaki K
Magn Reson Med Sci 2011;10(4):251-4. doi: 10.2463/mrms.10.251. PMID: 22214910

Adenomyosis.

Siegler AM, Camilien L
J Reprod Med 1994 Nov;39(11):841-53. PMID: 7853271

Chronic ectopic pregnancy: ultrasonic diagnosis.

Rogers WF, Shaub M, Wilson R
J Clin Ultrasound 1977 Aug;5(4):257-60. doi: 10.1002/jcu.1870050409. PMID: 407256

See all (152)

Therapy

Clinical practice. Uterine fibroids.

Stewart EA
N Engl J Med 2015 Apr 23;372(17):1646-55. doi: 10.1056/NEJMcp1411029. PMID: 25901428

Diagnosis and initial management of dysmenorrhea.

Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505

Malignant lymphoma of uterus: a case report with a review of the literature.

Agrawal A, Ofili G, Allan TL, Mann BS
Aust N Z J Obstet Gynaecol 2000 Aug;40(3):358-60. doi: 10.1111/j.1479-828x.2000.tb03353.x. PMID: 11065052

Abdominopelvic MR imaging in the nonobstetric evaluation of pregnant patients.

Forstner R, Kalbhen CL, Filly RA, Hricak H
AJR Am J Roentgenol 1996 May;166(5):1139-44. doi: 10.2214/ajr.166.5.8615258. PMID: 8615258

Report on the sue of the Dalkon Shield intrauterine device.

Sadovsky E, Yarkoni S, Anteby SO
Contraception 1974 Nov;10(5):475-80. doi: 10.1016/0010-7824(74)90114-0. PMID: 4448061

See all (80)

Prognosis

Characteristics of ovarian endometrioma during pregnancy.

Takami M, Kajiyama R, Miyagi E, Aoki S
J Obstet Gynaecol Res 2021 Sep;47(9):3250-3256. Epub 2021 Jun 21 doi: 10.1111/jog.14862. PMID: 34155737

Reproductive outcomes after hydatiform mole and gestational trophoblastic neoplasia.

Gadducci A, Lanfredini N, Cosio S
Gynecol Endocrinol 2015;31(9):673-8. Epub 2015 Aug 18 doi: 10.3109/09513590.2015.1054803. PMID: 26288335

Diagnosis and initial management of dysmenorrhea.

Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505

Malignant lymphoma of uterus: a case report with a review of the literature.

Agrawal A, Ofili G, Allan TL, Mann BS
Aust N Z J Obstet Gynaecol 2000 Aug;40(3):358-60. doi: 10.1111/j.1479-828x.2000.tb03353.x. PMID: 11065052

Is this patient pregnant? Can you reliably rule in or rule out early pregnancy by clinical examination?

Bastian LA, Piscitelli JT
JAMA 1997 Aug 20;278(7):586-91. doi: 10.1001/jama.278.7.586. PMID: 9268281

See all (64)

Clinical prediction guides

Ovarian tissue biopsy for cryopreservation by vaginal natural orifice transluminal endoscopic surgery: a new approach for a minimal invasive ovarian biopsy.

Seracchioli R, Maletta M, Pazzaglia E, Raffone A, Vicenti R, Scarperi S, Bergamini V, Raimondo D
Fertil Steril 2024 Aug;122(2):385-387. Epub 2024 Apr 9 doi: 10.1016/j.fertnstert.2024.04.005. PMID: 38604263

Myoma expulsion after embolization: case report and literature review.

Silva MCA, da Costa REAR, Júnior WOS, Carvalho AP, Vieira SC
Pan Afr Med J 2022;43:210. Epub 2022 Dec 28 doi: 10.11604/pamj.2022.43.210.38030. PMID: 36942141 Free PMC Article

Characteristics of ovarian endometrioma during pregnancy.

Takami M, Kajiyama R, Miyagi E, Aoki S
J Obstet Gynaecol Res 2021 Sep;47(9):3250-3256. Epub 2021 Jun 21 doi: 10.1111/jog.14862. PMID: 34155737

History of adenomyosis.

Benagiano G, Brosens I
Best Pract Res Clin Obstet Gynaecol 2006 Aug;20(4):449-63. Epub 2006 Mar 2 doi: 10.1016/j.bpobgyn.2006.01.007. PMID: 16515887

Reproductive hormones and stress urinary incontinence in pregnancy.

Kristiansson P, Samuelsson E, von Schoultz B, Svärdsudd K
Acta Obstet Gynecol Scand 2001 Dec;80(12):1125-30. doi: 10.1034/j.1600-0412.2001.801209.x. PMID: 11846710

See all (52)

Recent systematic reviews

A Case Series of Patients with Large Uterine Fibroids and Venous Thromboembolisms.

Cai E, Shao YH, Suarthana E, Bergeron A, Mansour FW, Krishnamurthy S
J Obstet Gynaecol Can 2021 Mar;43(3):352-360. Epub 2020 Nov 5 doi: 10.1016/j.jogc.2020.10.009. PMID: 33303409

See all (1)

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Enlarged uterus

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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