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Nasal dryness

MedGen UID:
534120
•Concept ID:
C0231919
•
Finding
Synonym: Nasal mucosa dry
SNOMED CT: Nasal mucosa dry (42201002); Nasal dryness (42201002)
 
HPO: HP:0033521

Definition

A lack of humidification of the nasal mucosa. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasal dryness

Professional guidelines

PubMed

Evaluation of Nasal Mucociliary Clearance, Nasal Obstruction Symptom Evaluation, and Epistaxis Severity Score in Isotretinoin Treatment.
İşlek A, Yıldız MG
Ear Nose Throat J 2021 Sep;100(8):566-569. Epub 2020 Apr 13 doi: 10.1177/0145561320920425. PMID: 32283974
Nasal vestibulitis: an under-recognized and under-treated side effect of cancer treatment?
Cathcart-Rake E, Smith D, Zahrieh D, Jatoi A, Yang P, Loprinzi CL
Support Care Cancer 2018 Nov;26(11):3909-3914. Epub 2018 May 24 doi: 10.1007/s00520-018-4261-7. PMID: 29797079
Treatment of obstructive sleep apnea in primary care.
Victor LD
Am Fam Physician 2004 Feb 1;69(3):561-8. PMID: 14971838

Recent clinical studies

Etiology

Limited Systemic Exposure with Topical Glycopyrronium Tosylate in Primary Axillary Hyperhidrosis.
Pariser DM, Lain EL, Mamelok RD, Drew J, Mould DR
Clin Pharmacokinet 2021 May;60(5):665-676. Epub 2021 Jan 12 doi: 10.1007/s40262-020-00975-y. PMID: 33433785Free PMC Article
Does Nasal Secretion Decrease in Sjögren Syndrome and Does This Affect Nasal Function?
Eren E, Balcı K, Gerçik Ö, Kabadayı G, Akar S
Laryngoscope 2021 Feb;131(2):370-373. Epub 2020 Aug 11 doi: 10.1002/lary.29022. PMID: 32780886
How does radioactive iodine affect the nose?
Server EA, Kirgezen T, Celebi OO, Yildiz M, Yigit O, Cermik TF
Laryngoscope 2017 Dec;127(12):2698-2702. Epub 2017 May 12 doi: 10.1002/lary.26652. PMID: 28498633
Intranasal ipratropium bromide for the common cold.
AlBalawi ZH, Othman SS, Alfaleh K
Cochrane Database Syst Rev 2013 Jun 19;2013(6):CD008231. doi: 10.1002/14651858.CD008231.pub3. PMID: 23784858Free PMC Article
The impact of nasal surgery on air-conditioning of the nasal airways.
Kastl KG, Rettinger G, Keck T
Rhinology 2009 Sep;47(3):237-41. doi: 10.4193/Rhin08.014. PMID: 19839243

Diagnosis

Evaluation of Nasal Mucociliary Clearance, Nasal Obstruction Symptom Evaluation, and Epistaxis Severity Score in Isotretinoin Treatment.
İşlek A, Yıldız MG
Ear Nose Throat J 2021 Sep;100(8):566-569. Epub 2020 Apr 13 doi: 10.1177/0145561320920425. PMID: 32283974
Nasal vestibulitis: an under-recognized and under-treated side effect of cancer treatment?
Cathcart-Rake E, Smith D, Zahrieh D, Jatoi A, Yang P, Loprinzi CL
Support Care Cancer 2018 Nov;26(11):3909-3914. Epub 2018 May 24 doi: 10.1007/s00520-018-4261-7. PMID: 29797079
Empty nose syndrome.
Kuan EC, Suh JD, Wang MB
Curr Allergy Asthma Rep 2015 Jan;15(1):493. doi: 10.1007/s11882-014-0493-x. PMID: 25430954
Chronic rhinosinusitis: management for optimal outcomes.
Aukema AA, Fokkens WJ
Treat Respir Med 2004;3(2):97-105. doi: 10.2165/00151829-200403020-00004. PMID: 15182211
Treatment of obstructive sleep apnea in primary care.
Victor LD
Am Fam Physician 2004 Feb 1;69(3):561-8. PMID: 14971838

Therapy

Evaluation of Nasal Mucociliary Clearance, Nasal Obstruction Symptom Evaluation, and Epistaxis Severity Score in Isotretinoin Treatment.
İşlek A, Yıldız MG
Ear Nose Throat J 2021 Sep;100(8):566-569. Epub 2020 Apr 13 doi: 10.1177/0145561320920425. PMID: 32283974
How does radioactive iodine affect the nose?
Server EA, Kirgezen T, Celebi OO, Yildiz M, Yigit O, Cermik TF
Laryngoscope 2017 Dec;127(12):2698-2702. Epub 2017 May 12 doi: 10.1002/lary.26652. PMID: 28498633
Empty nose syndrome.
Kuan EC, Suh JD, Wang MB
Curr Allergy Asthma Rep 2015 Jan;15(1):493. doi: 10.1007/s11882-014-0493-x. PMID: 25430954
Intranasal ipratropium bromide for the common cold.
AlBalawi ZH, Othman SS, Alfaleh K
Cochrane Database Syst Rev 2013 Jun 19;2013(6):CD008231. doi: 10.1002/14651858.CD008231.pub3. PMID: 23784858Free PMC Article
Chronic rhinosinusitis: management for optimal outcomes.
Aukema AA, Fokkens WJ
Treat Respir Med 2004;3(2):97-105. doi: 10.2165/00151829-200403020-00004. PMID: 15182211

Prognosis

How reliable is anamnestic data in predicting the clinical relevance of house dust mite sensitization?
Englhard AS, Holzer M, Eder K, Gellrich D, Gröger M
Eur Arch Otorhinolaryngol 2022 Feb;279(2):801-810. Epub 2021 May 21 doi: 10.1007/s00405-021-06862-x. PMID: 34019148Free PMC Article
Non-invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnoea.
Barbosa FT, Silva MP, Fontes LES, Pachito DV, Melnik T, Riera R
Cochrane Database Syst Rev 2021 Sep 23;9(9):CD013169. doi: 10.1002/14651858.CD013169.pub2. PMID: 34555186Free PMC Article
Middle turbinate resection is unlikely to cause empty nose syndrome in first year postoperatively.
Law RH, Ahmed AM, Van Harn M, Craig JR
Am J Otolaryngol 2021 Jul-Aug;42(4):102931. Epub 2021 Jan 26 doi: 10.1016/j.amjoto.2021.102931. PMID: 33550027
The spectrum of nasal involvement in systemic lupus erythematosus and its association with the disease activity.
Kusyairi KA, Gendeh BS, Sakthiswary R, Shaharir SS, Haizlene AH, Yusof KH
Lupus 2016 Apr;25(5):520-4. Epub 2015 Dec 11 doi: 10.1177/0961203315622279. PMID: 26657735
Compliance with continuous positive airway pressure therapy: assessing and improving treatment outcomes.
Zozula R, Rosen R
Curr Opin Pulm Med 2001 Nov;7(6):391-8. doi: 10.1097/00063198-200111000-00005. PMID: 11706314

Clinical prediction guides

Limited Systemic Exposure with Topical Glycopyrronium Tosylate in Primary Axillary Hyperhidrosis.
Pariser DM, Lain EL, Mamelok RD, Drew J, Mould DR
Clin Pharmacokinet 2021 May;60(5):665-676. Epub 2021 Jan 12 doi: 10.1007/s40262-020-00975-y. PMID: 33433785Free PMC Article
Does Nasal Secretion Decrease in Sjögren Syndrome and Does This Affect Nasal Function?
Eren E, Balcı K, Gerçik Ö, Kabadayı G, Akar S
Laryngoscope 2021 Feb;131(2):370-373. Epub 2020 Aug 11 doi: 10.1002/lary.29022. PMID: 32780886
Evaluation of Nasal Mucociliary Clearance, Nasal Obstruction Symptom Evaluation, and Epistaxis Severity Score in Isotretinoin Treatment.
İşlek A, Yıldız MG
Ear Nose Throat J 2021 Sep;100(8):566-569. Epub 2020 Apr 13 doi: 10.1177/0145561320920425. PMID: 32283974
How does radioactive iodine affect the nose?
Server EA, Kirgezen T, Celebi OO, Yildiz M, Yigit O, Cermik TF
Laryngoscope 2017 Dec;127(12):2698-2702. Epub 2017 May 12 doi: 10.1002/lary.26652. PMID: 28498633
Compliance with continuous positive airway pressure therapy: assessing and improving treatment outcomes.
Zozula R, Rosen R
Curr Opin Pulm Med 2001 Nov;7(6):391-8. doi: 10.1097/00063198-200111000-00005. PMID: 11706314

Recent systematic reviews

A Systematic Review and Meta-Analysis of Management Options for Empty Nose Syndrome: A Proposed Management Algorithm.
Hussain S, Hayat J, Almhanedi H, Alherz M, Ebrahim M, Lari A, Thamboo A
Otolaryngol Head Neck Surg 2025 Jan;172(1):1-12. Epub 2024 Aug 10 doi: 10.1002/ohn.929. PMID: 39126290
Non-invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnoea.
Barbosa FT, Silva MP, Fontes LES, Pachito DV, Melnik T, Riera R
Cochrane Database Syst Rev 2021 Sep 23;9(9):CD013169. doi: 10.1002/14651858.CD013169.pub2. PMID: 34555186Free PMC Article
Screening for Obstructive Sleep Apnea in Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force.
Jonas DE, Amick HR, Feltner C, Weber RP, Arvanitis M, Stine A, Lux L, Harris RP
JAMA 2017 Jan 24;317(4):415-433. doi: 10.1001/jama.2016.19635. PMID: 28118460
Intranasal ipratropium bromide for the common cold.
AlBalawi ZH, Othman SS, Alfaleh K
Cochrane Database Syst Rev 2013 Jun 19;2013(6):CD008231. doi: 10.1002/14651858.CD008231.pub3. PMID: 23784858Free PMC Article
Intranasal ipratropium bromide for the common cold.
Albalawi ZH, Othman SS, Alfaleh K
Cochrane Database Syst Rev 2011 Jul 6;(7):CD008231. doi: 10.1002/14651858.CD008231.pub2. PMID: 21735425

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