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Benign neoplasm of brain

MedGen UID:
99225
Concept ID:
C0496899
Neoplastic Process
Synonyms: Benign Brain Neoplasm; Benign Brain Neoplasms; Benign Neoplasm, Brain; Benign Neoplasms, Brain; Brain Benign Neoplasm; Brain Benign Neoplasms; Brain Neoplasm, Benign; Brain Neoplasms, Benign; Neoplasms, Brain, Benign
SNOMED CT: Benign brain tumor (92030004); Benign neoplasm of brain (92030004)
 
Monarch Initiative: MONDO:0021451

Definition

A neoplasm that arises from the brain and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Czarnywojtek A, Borowska M, Dyrka K, Van Gool S, Sawicka-Gutaj N, Moskal J, Kościński J, Graczyk P, Hałas T, Lewandowska AM, Czepczyński R, Ruchała M
Pharmacology 2023;108(5):423-431. Epub 2023 Jul 17 doi: 10.1159/000531319. PMID: 37459849
McKinnon C, Nandhabalan M, Murray SA, Plaha P
BMJ 2021 Jul 14;374:n1560. doi: 10.1136/bmj.n1560. PMID: 34261630
Melmed S, Casanueva FF, Hoffman AR, Kleinberg DL, Montori VM, Schlechte JA, Wass JA; Endocrine Society
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Recent clinical studies

Etiology

Lapointe S, Perry A, Butowski NA
Lancet 2018 Aug 4;392(10145):432-446. Epub 2018 Jul 27 doi: 10.1016/S0140-6736(18)30990-5. PMID: 30060998
Mellinghoff IK, Gilbertson RJ
J Clin Oncol 2017 Jul 20;35(21):2343-2345. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.74.2965. PMID: 28640709
McNeill KA
Neurol Clin 2016 Nov;34(4):981-998. doi: 10.1016/j.ncl.2016.06.014. PMID: 27720005
Perkins A, Liu G
Am Fam Physician 2016 Feb 1;93(3):211-7. PMID: 26926614
Wells EM, Packer RJ
Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):373-96. doi: 10.1212/01.CON.0000464176.96311.d1. PMID: 25837902

Diagnosis

Surov A, Borggrefe J
Clin Cancer Res 2024 Nov 1;30(21):4813-4814. doi: 10.1158/1078-0432.CCR-24-2013. PMID: 39177581
Taylor LP, McGranahan TM, Venur VA
Semin Neurol 2023 Dec;43(6):808-809. Epub 2023 Dec 14 doi: 10.1055/s-0043-1776767. PMID: 38096848
Perkins A, Liu G
Am Fam Physician 2016 Feb 1;93(3):211-7. PMID: 26926614
Gállego Pérez-Larraya J, Hildebrand J
Handb Clin Neurol 2014;121:1143-57. doi: 10.1016/B978-0-7020-4088-7.00077-8. PMID: 24365409
Soffietti R, Ducati A, Rudà R
Handb Clin Neurol 2012;105:747-55. doi: 10.1016/B978-0-444-53502-3.00021-5. PMID: 22230531

Therapy

Rominiyi O, Vanderlinden A, Clenton SJ, Bridgewater C, Al-Tamimi Y, Collis SJ
Br J Cancer 2021 Feb;124(4):697-709. Epub 2020 Nov 4 doi: 10.1038/s41416-020-01136-5. PMID: 33144698Free PMC Article
Lima Fde M, Carvalho AL, Silva JC Jr, Amorim R, Dellaretti M, Wendling-Henriques LA, Maldaun M, Kirchhoff D, Botelho RV; Sociedade Brasileira de Neurocirurgia
Rev Assoc Med Bras (1992) 2016 Sep-Oct;62(5):389-94. doi: 10.1590/1806-9282.62.05.389. PMID: 27656846
Lin NU, Lee EQ, Aoyama H, Barani IJ, Barboriak DP, Baumert BG, Bendszus M, Brown PD, Camidge DR, Chang SM, Dancey J, de Vries EG, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wen PY; Response Assessment in Neuro-Oncology (RANO) group
Lancet Oncol 2015 Jun;16(6):e270-8. Epub 2015 May 27 doi: 10.1016/S1470-2045(15)70057-4. PMID: 26065612
Junck L
Handb Clin Neurol 2012;104:417-34. doi: 10.1016/B978-0-444-52138-5.00028-1. PMID: 22230458
Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, Macdonald JS, Young B
N Engl J Med 1990 Feb 22;322(8):494-500. doi: 10.1056/NEJM199002223220802. PMID: 2405271

Prognosis

Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2019 Nov 1;21(Suppl 5):v1-v100. doi: 10.1093/neuonc/noz150. PMID: 31675094Free PMC Article
Witthayanuwat S, Pesee M, Supaadirek C, Supakalin N, Thamronganantasakul K, Krusun S
Asian Pac J Cancer Prev 2018 Sep 26;19(9):2613-2617. doi: 10.22034/APJCP.2018.19.9.2613. PMID: 30256068Free PMC Article
Cagney DN, Martin AM, Catalano PJ, Redig AJ, Lin NU, Lee EQ, Wen PY, Dunn IF, Bi WL, Weiss SE, Haas-Kogan DA, Alexander BM, Aizer AA
Neuro Oncol 2017 Oct 19;19(11):1511-1521. doi: 10.1093/neuonc/nox077. PMID: 28444227Free PMC Article
Sul J, Posner JB
Cancer Treat Res 2007;136:1-21. doi: 10.1007/978-0-387-69222-7_1. PMID: 18078262
Sanford RA, Gajjar A
Clin Neurosurg 1997;44:559-70. PMID: 10080027

Clinical prediction guides

Harlianto NI
Radiol Imaging Cancer 2024 Sep;6(5):e249016. doi: 10.1148/rycan.249016. PMID: 39177471Free PMC Article
Li G, Wu F, Zeng F, Zhai Y, Feng Y, Chang Y, Wang D, Jiang T, Zhang W
CNS Neurosci Ther 2021 Feb;27(2):186-195. Epub 2020 Oct 16 doi: 10.1111/cns.13464. PMID: 33063446Free PMC Article
Suh JH, Kotecha R, Chao ST, Ahluwalia MS, Sahgal A, Chang EL
Nat Rev Clin Oncol 2020 May;17(5):279-299. Epub 2020 Feb 20 doi: 10.1038/s41571-019-0320-3. PMID: 32080373
Davis ME
Semin Oncol Nurs 2018 Dec;34(5):420-429. Epub 2018 Nov 2 doi: 10.1016/j.soncn.2018.10.001. PMID: 30392758
Peterson K, Cairncross JG
Neurol Clin 1995 Nov;13(4):861-73. PMID: 8584001

Recent systematic reviews

Li Y, Liu Y, Liang Y, Wei R, Zhang W, Yao W, Luo S, Pang X, Wang Y, Jiang X, Lai S, Yang R
Eur Radiol 2022 Nov;32(11):8039-8051. Epub 2022 May 19 doi: 10.1007/s00330-022-08828-x. PMID: 35587827
Gondi V, Bauman G, Bradfield L, Burri SH, Cabrera AR, Cunningham DA, Eaton BR, Hattangadi-Gluth JA, Kim MM, Kotecha R, Kraemer L, Li J, Nagpal S, Rusthoven CG, Suh JH, Tomé WA, Wang TJC, Zimmer AS, Ziu M, Brown PD
Pract Radiat Oncol 2022 Jul-Aug;12(4):265-282. Epub 2022 May 6 doi: 10.1016/j.prro.2022.02.003. PMID: 35534352
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Ziu M, Goyal S, Olson JJ
J Neurooncol 2022 Jun;158(2):255-264. Epub 2021 Nov 8 doi: 10.1007/s11060-021-03857-w. PMID: 34748120
Rosenfelder N, Khoo V
BMJ Clin Evid 2011 Jul 26;2011 PMID: 21791125Free PMC Article

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