BioAssays, Active for PubChem Compound (Select 77844888) - PubChem BioAssay - NCBI

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Select item 20415181.

% Enzyme Activity of Urokinase in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Urokinase-type plasminogen activator

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041518

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 20415172.

% Enzyme Activity of Tryptase g1 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Tryptase gamma

Assay data:1 Active, 1 Tested

AID:: 2041517

Summary Compounds, Active Related BioAssays by Target

Select item 20415163.

% Enzyme Activity of Tryptase b2 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Tryptase beta-2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041516

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 20415154.

% Enzyme Activity of Trypsin in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Trypsin-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041515

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 20415145.

% Enzyme Activity of TMPRS11D in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Transmembrane protease serine 11D

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041514

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 20415136.

% Enzyme Activity of Thrombin a in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Prothrombin

Assay data:1 Active, 1 Tested

AID:: 2041513

Summary Compounds, Active Related BioAssays by Target

Select item 20415127.

% Enzyme Activity of TACE in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Disintegrin and metalloproteinase domain-containing protein 17

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041512

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 20415118.

% Enzyme Activity of SARS-CoV2-Plpro in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Replicase polyprotein 1ab

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041511

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 20415109.

% Enzyme Activity of Proteinase K in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Proteinase K

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041510

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150810.

% Enzyme Activity of Plasmin in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Plasminogen

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041508

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150711.

% Enzyme Activity of Plasma Kallikrein in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Plasma kallikrein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041507

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150612.

% Enzyme Activity of Papain in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Papain

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041506

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150513.

% Enzyme Activity of Neprilysin in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Neprilysin

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041505

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150414.

% Enzyme Activity of MMP14 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-14

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041504

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150315.

% Enzyme Activity of MMP13 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Collagenase 3

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041503

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150216.

% Enzyme Activity of MMP12 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Macrophage metalloelastase

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041502

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150117.

% Enzyme Activity of MMP10 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Stromelysin-2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041501

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204150018.

% Enzyme Activity of MMP9 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041500

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204149919.

% Enzyme Activity of MMP8 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041499

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204149820.

% Enzyme Activity of MMP7 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Matrilysin

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041498

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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BioActivity

Active Compounds (47)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (15)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (45)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (47)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (3)
BioAssays extracted from the literature
Other (44)
BioAssays deposited by other experimentalists

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