PubChem BioAssay Links for Taxonomy (Select 10090) - PubChem BioAssay - NCBI

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Items: 1 to 20 of 230623

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Select item 20418641.

Inhibition of Nitric Oxide Synthetase, Inducible (iNOS) at 10.0 M in the Eurofins Panlabs Safety Screen

Source:: ChEMBL

Protein Target:: Nitric oxide synthase, inducible

Assay data:1 Tested

AID:: 2041864

Summary Related BioAssays by Target

Select item 20417432.

Inhibition of Nitric Oxide Synthetase, Inducible (iNOS) at 10.0 M in the Eurofins Panlabs Safety Screen

Source:: ChEMBL

Protein Target:: Nitric oxide synthase, inducible

Assay data:1 Tested

AID:: 2041743

Summary Related BioAssays by Target

Select item 20417003.

METAP2 biochemical assay (mouse)

Source:: ChEMBL

Protein Target:: Methionine aminopeptidase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041700

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 20416784.

Activity against SOMATOS/MO in the Eurofins Panlabs screen (BI) by Radioactive Assay

Source:: ChEMBL

Protein Target:: Somatostatin receptor type 5

Assay data:1 Tested

AID:: 2041678

Summary Related BioAssays by Target

Select item 20416715.

Inhibitor of PHORBOLE/M in the Eurofins Panlabs screen (BI) by Radioactive Assay

Source:: ChEMBL

Assay data:1 Tested

AID:: 2041671

Select item 20416426.

Activity against INOS in the Eurofins Panlabs screen (BI) by absorption of electromagnetic radiation

Source:: ChEMBL

Protein Target:: Nitric oxide synthase, inducible

Assay data:1 Tested

AID:: 2041642

Summary Related BioAssays by Target

Select item 20416397.

Activity against IL-1ALPHA/M in the Eurofins Panlabs screen (BI) by Radioactive Assay

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor type 1

Assay data:1 Tested

AID:: 2041639

Summary Related BioAssays by Target

Select item 20416138.

Activity against CCKB/M in the Eurofins Panlabs screen (BI)

Source:: ChEMBL

Protein Target:: Gastrin/cholecystokinin type B receptor

Assay data:1 Tested

AID:: 2041613

Summary Related BioAssays by Target

Select item 20415489.

Activity against SOMATOS/M in the Eurofins SafetyScreen44 (BI) by Radioactive Assay (Old_Cerep_36)

Source:: ChEMBL

Protein Target:: Somatostatin receptor type 5

Assay data:1 Tested

AID:: 2041548

Summary Related BioAssays by Target

Select item 204154410.

Activity against PDGF/M in the Eurofins SafetyScreen44 (BI) (Old_Cerep_33)

Source:: ChEMBL

Protein Targets:: Platelet-derived growth factor receptor alpha; ...
Total:: 2

Assay data:1 Tested

AID:: 2041544

Summary Related BioAssays by Target

Select item 204148611.

% Enzyme Activity of Caspase 11 in the Reaction Biology protease panel at 1.0 M

Source:: ChEMBL

Protein Target:: Caspase-4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041486

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204147112.

ELANE inhibitor assay (mouse)

Source:: ChEMBL

Protein Target:: Neutrophil elastase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041471

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204117813.

Affinity On-target Cellular interaction: (Immunoblotting (inhibition of FGFR1 autophosphorylation in NIH 3T3 cells)) EUB0000699a FGFR1

Source:: ChEMBL

Protein Target:: Fibroblast growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041178

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204117614.

Affinity On-target Cellular interaction: (Luciferase bioluminescent assay (Bright-Glo, Promega, proliferation assay in BaF3 Cell line)) EUB0000678a FGFR3

Source:: ChEMBL

Protein Target:: Fibroblast growth factor receptor 3

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041176

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204117515.

Affinity On-target Cellular interaction: (Luciferase bioluminescent assay (Bright-Glo, Promega, proliferation assay in BaF3 Cell line)) EUB0000678a FGFR2

Source:: ChEMBL

Protein Target:: Fibroblast growth factor receptor 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041175

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204117416.

Affinity On-target Cellular interaction: (Luciferase bioluminescent assay (Bright-Glo, Promega, proliferation assay in BaF3 Cell line)) EUB0000678a FGFR1

Source:: ChEMBL

Protein Target:: Fibroblast growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041174

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204117317.

Affinity On-target Cellular interaction: (Whole cell assay (murine colon 26 (C26) carcinoma cells)) EUB0000666a MAP2K1

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041173

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204117218.

Affinity On-target Cellular interaction: (SureFire pSTAT5 Assay kit (phosphorylation of STAT5 in TEL-TYK2 engineered Ba/F3 cells)) EUB0000644a TYK2

Source:: ChEMBL

Protein Target:: Non-receptor tyrosine-protein kinase TYK2

Assay data:1 Active, 1 Tested

AID:: 2041172

Summary Compounds, Active Related BioAssays by Target

Select item 204117119.

Affinity On-target Cellular interaction: (SureFire pSTAT5 Assay kit (phosphorylation of STAT5 in TEL-JAK2 engineered Ba/F3 cells)) EUB0000644a JAK2

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041171

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 204117020.

Affinity On-target Cellular interaction: (SureFire pSTAT5 Assay kit (phosphorylation of STAT5 in BCR-JAK1 Ba/F3 engineered cells)) EUB0000644a JAK1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 2041170

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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Proteins (200)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (48,227)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1,402)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (12,256)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
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Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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BioAssays extracted from the literature
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BioAssays deposited by the NIH Molecular Libraries Program
Other (3,121)
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