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Select item 106208221.

CENPA functions as a transcriptional regulator to promote hepatocellular carcinoma progression via cooperating with YY1

Jingyu Liao, Zeyu Chen, Ruizhi Chang, Tong Yuan, Ganxun Li, Chang Zhu, Jingyuan Wen, Yi Wei, Zhao Huang, Zeyang Ding, Liang Chu, Junnan Liang, Bixiang Zhang

Int J Biol Sci. 2023; 19(16): 5218–5232. Published online 2023 Oct 16. doi: 10.7150/ijbs.85656

PMCID:: PMC10620822

Article PDF–9.0M

Select item 95698282.

The Sequence Dependent Nanoscale Structure of CENP-A Nucleosomes

Tommy Stormberg, Yuri L. Lyubchenko

Int J Mol Sci. 2022 Oct; 23(19): 11385. Published online 2022 Sep 27. doi: 10.3390/ijms231911385

PMCID:: PMC9569828

Article PDF–6.7M

Select item 86431063.

Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A^K124ub

Catalina Salinas-Luypaert, Praveen Kumar Allu, Glennis A. Logsdon, Jennine M. Dawicki-McKenna, Craig W. Gambogi, Daniele Fachinetti, Ben E. Black

Cell Rep. Author manuscript; available in PMC 2021 Dec 4.

Published in final edited form as: Cell Rep. 2021 Nov 2; 37(5): 109924. doi: 10.1016/j.celrep.2021.109924

PMCID:: PMC8643106

Article PDF–1.9M

Select item 79583894.

CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

Simona Giunta, Solène Hervé, Ryan R. White, Therese Wilhelm, Marie Dumont, Andrea Scelfo, Riccardo Gamba, Cheng Kit Wong, Giulia Rancati, Agata Smogorzewska, Hironori Funabiki, Daniele Fachinetti

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2015634118. Published online 2021 Mar 2. doi: 10.1073/pnas.2015634118

PMCID:: PMC7958389

Article PDF–1.8M

Select item 79059985.

CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity

Roshan L. Shrestha, Austin Rossi, Darawalee Wangsa, Ann K. Hogan, Kimberly S. Zaldana, Evelyn Suva, Yang Jo Chung, Chelsea L. Sanders, Simone Difilippantonio, Tatiana S. Karpova, Baktiar Karim, Daniel R. Foltz, Daniele Fachinetti, Peter D. Aplan, Thomas Ried, Munira A. Basrai

J Cell Biol. 2021 Apr 5; 220(4): e202007195. Published online 2021 Feb 23. doi: 10.1083/jcb.202007195

PMCID:: PMC7905998

Article PDF–8.5M

Select item 76597256.

Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control

Sreyoshi Mitra, Bharath Srinivasan, Lars E.T. Jansen

J Cell Biol. 2020 Oct 5; 219(10): e202005099. Published online 2020 Sep 15. doi: 10.1083/jcb.202005099

PMCID:: PMC7659725

Article PDF–3.2M

Select item 76127577.

Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome

Stanislau Yatskevich, Kyle W. Muir, Dom Bellini, Ziguo Zhang, Jing Yang, Thomas Tischer, Masa Predin, Tom Dendooven, Stephen H. McLaughlin, David Barford

Science. Author manuscript; available in PMC 2022 Jun 20.

Published in final edited form as: Science. 2022 May 20; 376(6595): 844–852. Published online 2022 Apr 14. doi: 10.1126/science.abn3810

PMCID:: PMC7612757

Article PDF–3.4M

Select item 73970308.

Guarding the Genome: CENP-A-Chromatin in Health and Cancer

Megan A. Mahlke, Yael Nechemia-Arbely

Genes (Basel) 2020 Jul; 11(7): 810. Published online 2020 Jul 16. doi: 10.3390/genes11070810

PMCID:: PMC7397030

Article PDF–2.6M

Select item 73071899.

The role of the histone H3 variant CENPA in prostate cancer

Anjan K. Saha, Rafael Contreras-Galindo, Yashar S. Niknafs, Matthew Iyer, Tingting Qin, Karthik Padmanabhan, Javed Siddiqui, Monica Palande, Claire Wang, Brian Qian, Elizabeth Ward, Tara Tang, Scott A. Tomlins, Scott D. Gitlin, Maureen A. Sartor, Gilbert S. Omenn, Arul M. Chinnaiyan, David M. Markovitz

J Biol Chem. 2020 Jun 19; 295(25): 8537–8549. Published online 2020 May 5. doi: 10.1074/jbc.RA119.010080

PMCID:: PMC7307189

Article PDF–4.1M

Select item 716869310.

The Oncogenic Role of CENPA in Hepatocellular Carcinoma Development: Evidence from Bioinformatic Analysis

Yuan Zhang, Lei Yang, Jia Shi, Yunfei Lu, Xiaorong Chen, Zongguo Yang

Biomed Res Int. 2020; 2020: 3040839. Published online 2020 Apr 8. doi: 10.1155/2020/3040839

PMCID:: PMC7168693

Article PDF–1.2M

Select item 701526611.

DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres

Yael Nechemia-Arbely, Karen H. Miga, Ofer Shoshani, Aaron Aslanian, Moira A. McMahon, Ah Young Lee, Daniele Fachinetti, John R. Yates, III, Bing Ren, Don W. Cleveland

Nat Cell Biol. Author manuscript; available in PMC 2020 Feb 12.

Published in final edited form as: Nat Cell Biol. 2019 Jun; 21(6): 743–754. Published online 2019 Jun 3. doi: 10.1038/s41556-019-0331-4

PMCID:: PMC7015266

Article PDF–3.5M

Select item 653466712.

Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment

Bing-Rui Zhou, K. N. Sathish Yadav, Mario Borgnia, Jingjun Hong, Baohua Cao, Ada L. Olins, Donald E. Olins, Yawen Bai, Ping Zhang

Nat Commun. 2019; 10: 2301. Published online 2019 May 24. doi: 10.1038/s41467-019-10247-4

PMCID:: PMC6534667

Article PDF–2.0M

Select item 632980713.

Phosphorylation of CENP-A on serine 7 does not control centromere function

Viviana Barra, Glennis A. Logsdon, Andrea Scelfo, Sebastian Hoffmann, Solène Hervé, Aaron Aslanian, Yael Nechemia-Arbely, Don W. Cleveland, Ben E. Black, Daniele Fachinetti

Nat Commun. 2019; 10: 175. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08073-1

PMCID:: PMC6329807

Article PDF–2.7M

Select item 575888014.

Nanoscale dynamics of centromere nucleosomes and the critical roles of CENP-A

Micah P Stumme-Diers, Siddhartha Banerjee, Mohtadin Hashemi, Zhiqiang Sun, Yuri L Lyubchenko

Nucleic Acids Res. 2018 Jan 9; 46(1): 94–103. Published online 2017 Oct 10. doi: 10.1093/nar/gkx933

PMCID:: PMC5758880

Article PDF–2.5M

Select item 556452315.

Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells

Roshan L. Shrestha, Grace S. Ahn, Mae I. Staples, Kizhakke M. Sathyan, Tatiana S. Karpova, Daniel R. Foltz, Munira A. Basrai

Oncotarget. 2017 Jul 18; 8(29): 46781–46800. Published online 2017 May 23. doi: 10.18632/oncotarget.18108

PMCID:: PMC5564523

Article PDF–2.0M

Select item 552218816.

Motifs in the amino-terminus of CENP-A are required for its accumulation within the nucleus and at the centromere

Ruiqi Jing, Jiajie Xi, Ye Leng, Wen Chen, Guiying Wang, Wenwen Jia, Jiuhong Kang, Songcheng Zhu

Oncotarget. 2017 Jun 20; 8(25): 40654–40667. Published online 2017 Apr 18. doi: 10.18632/oncotarget.17204

PMCID:: PMC5522188

Article PDF–12M

Select item 525051217.

A dual inhibitory mechanism sufficient to maintain cell cycle restricted CENP-A assembly

Ana Stankovic, Lucie Y. Guo, João F. Mata, Dani L. Bodor, Xing-Jun Cao, Aaron O. Bailey, Jeffrey Shabanowitz, Donald F. Hunt, Benjamin A. Garcia, Ben E. Black, Lars E.T Jansen

Mol Cell. Author manuscript; available in PMC 2017 Jan 20.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 231–246. Published online 2016 Dec 22. doi: 10.1016/j.molcel.2016.11.021

PMCID:: PMC5250512

Article PDF–2.8M

Select item 523535618.

CENP-A modifications on Ser68 and Lys124 are dispensable for establishment, maintenance, and long-term function of human centromeres

Daniele Fachinetti, Glennis A. Logsdon, Amira Abdullah, Evan B. Selzer, Don W. Cleveland, Ben E. Black

Dev Cell. Author manuscript; available in PMC 2018 Jan 9.

Published in final edited form as: Dev Cell. 2017 Jan 9; 40(1): 104–113. doi: 10.1016/j.devcel.2016.12.014

PMCID:: PMC5235356

Article PDF–973K

Select item 513489419.

CENP-A is dispensable for mitotic centromere function after initial centromere/kinetochore assembly

S Hoffmann, M Dumont, V. Barra, P Ly, Y Nechemia-Arbely, M.A. McMahon, S. Hervé, DW Cleveland, D. Fachinetti

Cell Rep. Author manuscript; available in PMC 2016 Dec 2.

Published in final edited form as: Cell Rep. 2016 Nov 22; 17(9): 2394–2404. doi: 10.1016/j.celrep.2016.10.084

PMCID:: PMC5134894

Article PDF–1.8M

Select item 509716920.

Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres

Wei-Hao Shang, Tetsuya Hori, Frederick G. Westhorpe, Kristina M. Godek, Atsushi Toyoda, Sadahiko Misu, Norikazu Monma, Kazuho Ikeo, Christopher W. Carroll, Yasunari Takami, Asao Fujiyama, Hiroshi Kimura, Aaron F. Straight, Tatsuo Fukagawa

Nat Commun. 2016; 7: 13465. Published online 2016 Nov 4. doi: 10.1038/ncomms13465