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Items: 1 to 20 of 231

1.
PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg N. Brooke, Hemanth Tummala, Madapura M. Pradeepa
Nat Commun. 2024; 15: 361. Published online 2024 Jan 8. doi: 10.1038/s41467-023-44544-w
Correction in:
Nat Commun. 2024; 15: 4865.
PMCID:
PMC10774266
ArticlePDF–5.8M
2.
The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells
Greisha L. Ortiz-Hernandez, Evelyn S. Sanchez-Hernandez, Pedro T. Ochoa, Catherine C. Elix, Hossam R. Alkashgari, James R. W. McMullen, Ubaldo Soto, Shannalee R. Martinez, Carlos J. Diaz Osterman, Michael Mahler, Sourav Roy, Carlos A. Casiano
Cells. 2021 Oct; 10(10): 2723. Published online 2021 Oct 12. doi: 10.3390/cells10102723
PMCID:
PMC8534522
ArticlePDF–7.7M
3.
LEDGF/p75 Is Required for an Efficient DNA Damage Response
Victoria Liedtke, Christian Schröder, Dirk Roggenbuck, Romano Weiss, Ralf Stohwasser, Peter Schierack, Stefan Rödiger, Lysann Schenk
Int J Mol Sci. 2021 Jun; 22(11): 5866. Published online 2021 May 30. doi: 10.3390/ijms22115866
PMCID:
PMC8198318
ArticlePDF–2.2M
4.
Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding
Haibo Wang, Lucas Farnung, Christian Dienemann, Patrick Cramer
Nat Struct Mol Biol. Author manuscript; available in PMC 2020 Jun 9.
Published in final edited form as: Nat Struct Mol Biol. 2020 Jan; 27(1): 8–13. Published online 2019 Dec 9. doi: 10.1038/s41594-019-0345-4
PMCID:
PMC6955156
ArticlePDF–4.8M
5.
PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes
Deepak K Singh, Omid Gholamalamdari, Mahdieh Jadaliha, Xiao Ling Li, Yo-Chuen Lin, Yang Zhang, Shuomeng Guang, Seyedsasan Hashemikhabir, Saumya Tiwari, Yuelin J Zhu, Abid Khan, Anu Thomas, Arindam Chakraborty, Virgilia Macias, Andre K Balla, Rohit Bhargava, Sarath Chandra Janga, Jian Ma, Supriya G Prasanth, Ashish Lal, Kannanganattu V Prasanth
Carcinogenesis. 2017 Oct; 38(10): 966–975. Published online 2017 Jun 17. doi: 10.1093/carcin/bgx062
PMCID:
PMC6410955
ArticlePDF–2.6M
6.
Clinical significance of anti-dense fine speckled 70 antibody in patients with fibromyalgia
Jisoo Jeong, Dong Hyun Kim, Gun Park, Suyeon Park, Hyun-Sook Kim
Korean J Intern Med. 2019 Mar; 34(2): 426–433. Published online 2017 Nov 24. doi: 10.3904/kjim.2016.276
PMCID:
PMC6406084
ArticlePDF–164K
7.
Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection
Yulia Lampi, Dominique Van Looveren, Lenard S. Vranckx, Irina Thiry, Simon Bornschein, Zeger Debyser, Rik Gijsbers
Sci Rep. 2019; 9: 2389. Published online 2019 Feb 20. doi: 10.1038/s41598-019-38718-0
PMCID:
PMC6382798
ArticlePDF–3.2M
8.
LEDGF/p75 Deficiency Increases Deletions at the HIV-1 cDNA Ends
Murilo T. D. Bueno, Daniel Reyes, Manuel Llano
Viruses. 2017 Sep; 9(9): 259. Published online 2017 Sep 15. doi: 10.3390/v9090259
PMCID:
PMC5618025
ArticlePDF–1.0M
9.
Targeting the stress oncoprotein LEDGF/p75 to sensitize chemoresistant prostate cancer cells to taxanes
Leslimar Ríos-Colón, Christina K. Cajigas-Du Ross, Anamika Basu, Catherine Elix, Ivana Alicea-Polanco, Tino W. Sanchez, Vinodh Radhakrishnan, Chien-Shing Chen, Carlos A. Casiano
Oncotarget. 2017 Apr 11; 8(15): 24915–24931. Published online 2017 Feb 14. doi: 10.18632/oncotarget.15323
PMCID:
PMC5421899
ArticlePDF–11M
10.
Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer
Juliet D. French, Sharon E. Johnatty, Yi Lu, Jonathan Beesley, Bo Gao, Murugan Kalimutho, Michelle J. Henderson, Amanda J. Russell, Siddhartha Kar, Xiaoqing Chen, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Martin O'Reilly, Chen Wang, Darren J. Korbie, Australian Ovarian Cancer Study Group, Australian Cancer Study, Diether Lambrechts, Evelyn Despierre, Els Van Nieuwenhuysen, Sandrina Lambrechts, Ignace Vergote, Beth Karlan, Jenny Lester, Sandra Orsulic, Christine Walsh, Peter A. Fasching, Matthias W. Beckmann, Arif B. Ekici, Alexander Hein, Keitaro Matsuo, Satoyo Hosono, Jacobus Pisterer, Peter Hillemanns, Toru Nakanishi, Yasushi Yatabe, Marc T. Goodman, Galina Lurie, Rayna K. Matsuno, Pamela J. Thompson, Tanja Pejovic, Yukie Bean, Florian Heitz, Philipp Harter, Andreas du Bois, Ira Schwaab, Estrid Hogdall, Susanne K. Kjaer, Allan Jensen, Claus Hogdall, Lene Lundvall, Svend Aage Engelholm, Bob Brown, James M. Flanagan, Michelle D. Metcalf, Nadeem Siddiqui, Thomas Sellers, Brooke Fridley, Julie Cunningham, Joellen M. Schildkraut, Ed Iversen, Rachel Palmieri Weber, Donal Brennan, Andrew Berchuck, Paul Pharoah, Paul Harnett, Murray D. Norris, Michelle Haber, Ellen L. Goode, Jason S. Lee, Kum Kum Khanna, Kerstin B. Meyer, Georgia Chenevix-Trench, Anna deFazio, Stacey L. Edwards, Stuart MacGregor
Oncotarget. 2016 Feb 9; 7(6): 6353–6368. Published online 2016 Jan 31. doi: 10.18632/oncotarget.7047
PMCID:
PMC4872719
ArticlePDF–4.1M
11.
LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes
Parmit Kumar Singh, Matthew R. Plumb, Andrea L. Ferris, James R. Iben, Xiaolin Wu, Hind J. Fadel, Brian T. Luke, Caroline Esnault, Eric M. Poeschla, Stephen H. Hughes, Mamuka Kvaratskhelia, Henry L. Levin
Genes Dev. 2015 Nov 1; 29(21): 2287–2297. doi: 10.1101/gad.267609.115
PMCID:
PMC4647561
ArticlePDF–301K
12.
Association of Single Nucleotide Polymorphisms in the Lens Epithelium-Derived Growth Factor (LEDGF/p75) with HIV-1 Infection Outcomes in Brazilian HIV-1+ Individuals
Caroline Pereira Bittencourt Passaes, Cynthia Chester Cardoso, Diogo Gama Caetano, Sylvia Lopes Maia Teixeira, Monick Lindenmeyer Guimarães, Dayse Pereira Campos, Valdilea Gonçalves Veloso, Dunja Z. Babic, Mario Stevenson, Milton Ozório Moraes, Mariza Gonçalves Morgado
PLoS One. 2014; 9(7): e101780. Published online 2014 Jul 21. doi: 10.1371/journal.pone.0101780
PMCID:
PMC4105638
ArticlePDF–378K
13.
Oncogenic Human Papillomaviruses Activate the Tumor-Associated Lens Epithelial-Derived Growth Factor (LEDGF) Gene
Jenny Leitz, Miriam Reuschenbach, Claudia Lohrey, Anja Honegger, Rosita Accardi, Massimo Tommasino, Manuel Llano, Magnus von Knebel Doeberitz, Karin Hoppe-Seyler, Felix Hoppe-Seyler
PLoS Pathog. 2014 Mar; 10(3): e1003957. Published online 2014 Mar 6. doi: 10.1371/journal.ppat.1003957
PMCID:
PMC3946365
ArticlePDF–10M
14.
Characterization of LEDGF/p75 Genetic Variants and Association with HIV-1 Disease Progression
Peter Messiaen, Ward De Spiegelaere, Jose Alcami, Karen Vervisch, Petra Van Acker, Bruno Verhasselt, Pieter Meuwissen, Esther Calonge, Nuria Gonzalez, Felix Gutierrez-Rodero, Carmen Rodriguez-Martín, Erica Sermijn, Bruce Poppe, Dirk Vogelaers, Chris Verhofstede, Linos Vandekerckhove
PLoS One. 2012; 7(11): e50204. Published online 2012 Nov 30. doi: 10.1371/journal.pone.0050204
PMCID:
PMC3511443
ArticlePDF–476K
15.
Expression of the Stress Response Oncoprotein LEDGF/p75 in Human Cancer: A Study of 21 Tumor Types
Anamika Basu, Heather Rojas, Hiya Banerjee, Irena B. Cabrera, Kayla Y. Perez, Marino De León, Carlos A. Casiano
PLoS One. 2012; 7(1): e30132. Published online 2012 Jan 19. doi: 10.1371/journal.pone.0030132
PMCID:
PMC3261859
ArticlePDF–488K
16.
Association of Polymorphisms in the LEDGF/p75 Gene (PSIP1) with Susceptibility to HIV-1 Infection and Disease Progression
Paradise Madlala, Rik Gijsbers, Frauke Christ, Anneleen Hombrouck, Lise Werner, Koleka Mlisana, Ping An, Salim S. Abdool Karim, Cheryl A. Winkler, Zeger Debyser, Thumbi Ndung'u
AIDS. Author manuscript; available in PMC 2012 Sep 10.
Published in final edited form as: AIDS. 2011 Sep 10; 25(14): 1711–1719. doi: 10.1097/QAD.0b013e328349c693
PMCID:
PMC3233670
ArticlePDF–1008K
17.
LEDGF1-326 Decreases P23H and Wild Type Rhodopsin Aggregates and P23H Rhodopsin Mediated Cell Damage in Human Retinal Pigment Epithelial Cells
Rinku Baid, Robert I. Scheinman, Toshimichi Shinohara, Dhirendra P. Singh, Uday B. Kompella
PLoS One. 2011; 6(9): e24616. Published online 2011 Sep 7. doi: 10.1371/journal.pone.0024616
PMCID:
PMC3168525
ArticlePDF–3.1M
18.
Alternative Splicing and Caspase-Mediated Cleavage Generate Antagonistic Variants of the Stress Oncoprotein LEDGF/p75
Terry A. Brown-Bryan, Lai S. Leoh, Vidya Ganapathy, Fabio J. Pacheco, Melanie Mediavilla-Varela, Maria Filippova, Thomas A. Linkhart, Rik Gijsbers, Zeger Debyser, Carlos A. Casiano
Mol Cancer Res. Author manuscript; available in PMC 2009 Dec 8.
Published in final edited form as: Mol Cancer Res. 2008 Aug; 6(8): 1293–1307. doi: 10.1158/1541-7786.MCR-08-0125
PMCID:
PMC2790462
ArticlePDF–3.1M
19.
LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro
Tien-sheng Huang, Line M Myklebust, Endre Kjarland, Bjørn Tore Gjertsen, Frederic Pendino, Øystein Bruserud, Stein Ove Døskeland, Johan R Lillehaug
Mol Cancer. 2007; 6: 31. Published online 2007 Apr 23. doi: 10.1186/1476-4598-6-31
PMCID:
PMC1876472
ArticlePDF–1.3M
20.
Human MCS5A1 Candidate Breast Cancer Susceptibility Gene FBXO10 Is Induced by Cellular Stress and Correlated with Lens Epithelium-Derived Growth Factor (LEDGF)
Xin Xu, David W. Powell, Courtney J. Lambring, Aaron H. Puckett, Lucas Deschenes, Russell A. Prough, Eric M. Poeschla, David J. Samuelson
Mol Carcinog. Author manuscript; available in PMC 2022 Dec 10.
Published in final edited form as: Mol Carcinog. 2014 Apr; 53(4): 300–313. Published online 2012 Nov 8. doi: 10.1002/mc.21977
PMCID:
PMC9737042
ArticlePDF–1.2M

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