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Items: 1 to 20 of 32

1.
Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2
Anutosh Chakraborty, J. Kent Werner, Jr., Michael A. Koldobskiy, Asif K. Mustafa, Krishna R. Juluri, Joseph Pietropaoli, Adele M. Snowman, Solomon H. Snyder
Proc Natl Acad Sci U S A. 2011 Feb 8; 108(6): 2205–2209. Published online 2011 Jan 24. doi: 10.1073/pnas.1019381108
PMCID:
PMC3038742
ArticlePDF–741K
2.
Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics
Bei H Morrison, Joseph A Bauer, Jiadi Hu, Ronald W Grane, Aylin M Ozdemir, Mamta Chawla-Sarkar, Bendi Gong, Alex Almasan, Dhananjaya V Kalvakolanu, Daniel J Lindner
Oncogene. Author manuscript; available in PMC 2007 Oct 29.
Published in final edited form as: Oncogene. 2002 Mar 14; 21(12): 1882–1889. doi: 10.1038/sj/onc/1205265
PMCID:
PMC2043497
ArticlePDF–366K
3.
IP6K Structure and the Molecular Determinants of Catalytic Specificity in an Inositol Phosphate Kinase Family
Huanchen Wang, Eugene F. DeRose, Robert E. London, Stephen B. Shears
Nat Commun. Author manuscript; available in PMC 2015 Jun 24.
Published in final edited form as: Nat Commun. 2014; 5: 4178. Published online 2014 Jun 24. doi: 10.1038/ncomms5178
PMCID:
PMC4141478
ArticlePDF–1.0M
4.
The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export
Miranda S. Wilson, Henning J. Jessen, Adolfo Saiardi
J Biol Chem. 2019 Jul 26; 294(30): 11597–11608. Published online 2019 Jun 11. doi: 10.1074/jbc.RA119.007848
PMCID:
PMC6663863
ArticlePDF–793K
5.
GENETICS OF GENE EXPRESSION IN PRIMARY IMMUNE CELLS IDENTIFIES CELL-SPECIFIC MASTER REGULATORS AND ROLES OF HLA ALLELES
Benjamin P Fairfax, Seiko Makino, Jayachandran Radhakrishnan, Katharine Plant, Stephen Leslie, Alexander Dilthey, Peter Ellis, Cordelia Langford, Fredrik O Vannberg, Julian C Knight
Nat Genet. Author manuscript; available in PMC 2012 Nov 1.
Published in final edited form as: Nat Genet. 2012 Mar 25; 44(5): 502–510. Published online 2012 Mar 25. doi: 10.1038/ng.2205
PMCID:
PMC3437404
ArticlePDF–2.5M
6.
p53-mediated apoptosis requires inositol hexakisphosphate kinase-2
Michael A. Koldobskiy, Anutosh Chakraborty, J. Kent Werner, Jr., Adele M. Snowman, Krishna R. Juluri, M. Scott Vandiver, Seyun Kim, Shira Heletz, Solomon H. Snyder
Proc Natl Acad Sci U S A. 2010 Dec 7; 107(49): 20947–20951. Published online 2010 Nov 15. doi: 10.1073/pnas.1015671107
PMCID:
PMC3000257
ArticlePDF–1.0M
7.
Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure/Activity Analysis.
Chunfang Gu, Michael A. Stashko, Ana C. Puhl-Rubio, Molee Chakraborty, Anutosh Chakraborty, Stephen V. Frye, Kenneth H. Pearce, Xiaodong Wang, Stephen B. Shears, Huanchen Wang
J Med Chem. Author manuscript; available in PMC 2019 Apr 17.
Published in final edited form as: J Med Chem. 2019 Feb 14; 62(3): 1443–1454. Published online 2019 Jan 25. doi: 10.1021/acs.jmedchem.8b01593
PMCID:
PMC6467728
ArticlePDF–1.0M
8.
Inositol Hexakisphosphate Kinase 2 Mediates Growth Suppressive and Apoptotic Effects of Interferon-β in Ovarian Carcinoma Cells
Bei H. Morrison, Joseph A. Bauer, Dhananjaya V. Kalvakolanu, Daniel J. Lindner
J Biol Chem. Author manuscript; available in PMC 2007 Oct 16.
Published in final edited form as: J Biol Chem. 2001 Jul 6; 276(27): 24965–24970. Published online 2001 May 3. doi: 10.1074/jbc.M101161200
PMCID:
PMC2025680
ArticlePDF–420K
9.
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2
Anutosh Chakraborty, Michael A. Koldobskiy, Katherine M. Sixt, Krishna R. Juluri, Asif K. Mustafa, Adele M. Snowman, Damian B. van Rossum, Randen L. Patterson, Solomon H. Snyder
Proc Natl Acad Sci U S A. 2008 Jan 29; 105(4): 1134–1139. Published online 2008 Jan 14. doi: 10.1073/pnas.0711168105
PMCID:
PMC2234104
ArticlePDF–907K
10.
Effect of Inositol Hexakisphosphate Kinase 2 on Transforming Growth Factor β-activated Kinase 1 and NF-κB Activation
Bei H. Morrison, Joseph A. Bauer, Joseph A. Lupica, Zhuo Tang, Heidi Szugye, Joseph A. DiDonato, Daniel J. Lindner
J Biol Chem. 2007 May 25; 282(21): 15349–15356. Published online 2020 Oct 2. doi: 10.1074/jbc.M700156200
PMCID:
PMC2048714
ArticlePDF–1.1M
11.
Tax1-binding protein 1 is expressed in the retina and interacts with the GABAC receptor ρ1 subunit
Melanie Ulrich, Silke Seeber, Cord-Michael Becker, Ralf Enz
Biochem J. 2007 Jan 15; 401(Pt 2): 429–436. Prepublished online 2006 Sep 25. Published online 2006 Dec 21. doi: 10.1042/BJ20061036
PMCID:
PMC1820818
ArticlePDF–1.2M
12.
The Regulation of Runx2 by FGF2 and Connexin43 Requires the Inositol Polyphosphate/Protein Kinase Cδ Cascade
Corinne Niger, Maria A. Luciotti, Atum M. Buo, Carla Hebert, Vy Ma, Joseph P. Stains
J Bone Miner Res. Author manuscript; available in PMC 2014 Jun 1.
Published in final edited form as: J Bone Miner Res. 2013 Jun; 28(6): 1468–1477. doi: 10.1002/jbmr.1867
PMCID:
PMC3657330
ArticlePDF–1.3M
13.
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4
PMCID:
PMC10869800
ArticlePDF–9.3M
14.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
ArticlePDF–706K
15.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
ArticlePDF–1.3M
16.
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt
Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi
Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115
PMCID:
PMC4358403
ArticlePDF–1.4M
17.
Large-Scale Concatenation cDNA Sequencing
Wei Yu, Björn Andersson, Kim C. Worley, Donna M. Muzny, Yan Ding, Wen Liu, Jennifer Y. Ricafrente, Meredith A. Wentland, Greg Lennon, Richard A. Gibbs
Genome Res. 1997 Apr; 7(4): 353–358. doi: 10.1101/gr.7.4.353
PMCID:
PMC139146
ArticlePDF–62K
18.
Leveraging the power of next-generation sequencing to generate interactome datasets
Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal
Nat Methods. Author manuscript; available in PMC 2011 Dec 1.
Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597
PMCID:
PMC3188388
ArticlePDF–932K
19.
Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions
Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano
Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604
PMCID:
PMC515316
ArticlePDF–181K
20.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
ArticlePDF–1.2M

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