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Items: 1 to 20 of 78

1.
High EMSY expression defines a BRCA‐like subgroup of high‐grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum
Robert L. Hollis, Michael Churchman, Caroline O. Michie, Tzyvia Rye, Laura Knight, Andrena McCavigan, Timothy Perren, Alistair R. W. Williams, W. Glenn McCluggage, Richard S. Kaplan, Gordon C. Jayson, Amit Oza, D. Paul Harkin, C. Simon Herrington, Richard Kennedy, Charlie Gourley
Cancer. 2019 Aug 15; 125(16): 2772–2781. Published online 2019 Jun 2. doi: 10.1002/cncr.32079
PMCID:
PMC6771827
ArticlePDF–1.1M
2.
EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis
Martina S. Elias, Sheila C. Wright, Judit Remenyi, James C. Abbott, Susan E. Bray, Christian Cole, Sharon Edwards, Marek Gierlinski, Mateusz Glok, John A. McGrath, William V. Nicholson, Lavinia Paternoster, Alan R. Prescott, Sara Ten Have, Phillip D. Whitfield, Angus I. Lamond, Sara J. Brown
J Allergy Clin Immunol. 2019 Aug; 144(2): 470–481. doi: 10.1016/j.jaci.2019.05.024
Correction in:
J Allergy Clin Immunol. 2020 Feb; 145(2): 723.
PMCID:
PMC6683598
Article
3.
Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families
Kirsi M. Määttä, Riikka Nurminen, Minna Kankuri-Tammilehto, Anne Kallioniemi, Satu-Leena Laasanen, Johanna Schleutker
BMC Cancer. 2017; 17: 496. Published online 2017 Jul 24. doi: 10.1186/s12885-017-3488-x
PMCID:
PMC5525221
ArticlePDF–687K
4.
The EMSY threonine 207 phospho-site is required for EMSY-driven suppression of DNA damage repair
Petar Jelinic, Laura A. Eccles, Jill Tseng, Paulina Cybulska, Monicka Wielgos, Simon N. Powell, Douglas A. Levine
Oncotarget. 2017 Feb 21; 8(8): 13792–13804. Published online 2017 Jan 13. doi: 10.18632/oncotarget.14637
PMCID:
PMC5355139
ArticlePDF–9.9M
5.
Polymorphisms in the airway epithelium related genes CDHR3 and EMSY are associated with asthma susceptibility
Miaomiao Zhang, Guo Chen, Yu Wang, Shou-Quan Wu, Andrew J. Sandford, Jian-Qing He
BMC Pulm Med. 2020; 20: 305. Published online 2020 Nov 19. doi: 10.1186/s12890-020-01334-0
PMCID:
PMC7678090
ArticlePDF–640K
6.
The EMSY Gene Collaborates with CCND1 in Non-Small Cell Lung Carcinogenesis
Onur Baykara, Nejat Dalay, Burak Bakir, Pelin Bulut, Kamil Kaynak, Nur Buyru
Int J Med Sci. 2017; 14(7): 675–679. Published online 2017 Jun 23. doi: 10.7150/ijms.19355
PMCID:
PMC5562119
ArticlePDF–300K
7.
The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31
Emmanuelle Viré, Christina Curtis, Veronica Davalos, Anna Git, Samuel Robson, Alberto Villanueva, August Vidal, Isaia Barbieri, Samuel Aparicio, Manel Esteller, Carlos Caldas, Tony Kouzarides
Mol Cell. 2014 Mar 6; 53(5): 806–818. doi: 10.1016/j.molcel.2014.01.029
Correction in:
Mol Cell. 2014 Apr 10; 54(1): 203.
PMCID:
PMC3988886
Article
8.
C11orf30-LRRC32 region is associated with total serum IgE levels in asthma
Xingnan Li, Elizabeth J. Ampleford, Timothy D. Howard, Wendy C. Moore, Huashi Li, William W. Busse, Mario Castro, Serpil C. Erzurum, Anne M. Fitzpatrick, Benjamin Gaston, Elliot Israel, Nizar N. Jarjour, W. Gerald Teague, Sally E. Wenzel, Gregory A. Hawkins, Eugene R. Bleecker, Deborah A. Meyers
J Allergy Clin Immunol. Author manuscript; available in PMC 2013 Feb 1.
Published in final edited form as: J Allergy Clin Immunol. 2012 Feb; 129(2): 575–578.e9. Published online 2011 Nov 8. doi: 10.1016/j.jaci.2011.09.040
PMCID:
PMC3268936
ArticlePDF–296K
9.
Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs
Patrick R Benusiglio, Fabienne Lesueur, Craig Luccarini, Joan McIntosh, Robert N Luben, Paula Smith, Alison Dunning, Douglas F Easton, Bruce AJ Ponder, Paul D Pharoah
BMC Cancer. 2005; 5: 81. Published online 2005 Jul 19. doi: 10.1186/1471-2407-5-81
PMCID:
PMC1185523
ArticlePDF–287K
10.
EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases
Isabelle Cousineau, Abdellah Belmaaza
Mol Genet Genomics. 2011; 285(4): 325–340. Published online 2011 Mar 16. doi: 10.1007/s00438-011-0612-5
PMCID:
PMC3064890
ArticlePDF–705K
11.
Allergy and glioma risk: test of association by genotype
Sara E Dobbins, Fay J Hosking, Sanjay Shete, Georgina Armstrong, Anthony Swerdlow, Yanhong Liu, Robert Yu, Ching Lau, Minouk Schoemaker, Sarah J Hepworth, Kenneth Muir, Melissa Bondy, Richard S Houlston
Int J Cancer. Author manuscript; available in PMC 2019 Mar 5.
Published in final edited form as: Int J Cancer. 2011 Apr 1; 128(7): 1736–1740. Published online 2010 May 25. doi: 10.1002/ijc.25483
PMCID:
PMC6400280
ArticlePDF–333K
12.
The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY
Scott A. Ezell, Christos Polytarchou, Maria Hatziapostolou, Ailan Guo, Ioannis Sanidas, Teeru Bihani, Michael J. Comb, George Sourvinos, Philip N. Tsichlis
Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10): E613–E621. Published online 2012 Feb 6. doi: 10.1073/pnas.1115029109
PMCID:
PMC3309773
ArticlePDF–1.2M
13.
EMSY inhibits homologous recombination repair and the interferon response promoting lung cancer immune evasion
Antonio Marzio, Emma Kurz, Jennifer M. Sahni, Giuseppe Di Feo, Joseph Puccini, Shaowen Jiang, Carolina Alcantara Hirsch, Arnaldo A. Arbini, Warren L. Wu, Harvey I. Pass, Dafna Bar-Sagi, Thales Papagiannakopoulos, Michele Pagano
Cell. Author manuscript; available in PMC 2023 Jan 6.
Published in final edited form as: Cell. 2022 Jan 6; 185(1): 169–183.e19. Published online 2021 Dec 27. doi: 10.1016/j.cell.2021.12.005
PMCID:
PMC8751279
ArticlePDF–2.6M
14.
Binding of EMSY to HP1β: implications for recruitment of HP1β and BS69
Caroline M S Ekblad, Gayatri B Chavali, Balaka P Basu, Stefan M V Freund, Dmitry Veprintsev, Luke Hughes-Davies, Tony Kouzarides, Aidan J Doherty, Laura S Itzhaki
EMBO Rep. 2005 Jul; 6(7): 675–680. Published online 2005 Jun 10. doi: 10.1038/sj.embor.7400415
PMCID:
PMC1369107
ArticlePDF–206K
15.
GWAS identifies four novel eosinophilic esophagitis loci
Patrick MA Sleiman, Mei-Lun Wang, Antonella Cianferoni, Seema Aceves, Nirmala Gonsalves, Kari Nadeau, Albert J. Bredenoord, Glenn T. Furuta, Jonathan M. Spergel, Hakon Hakonarson
Nat Commun. Author manuscript; available in PMC 2015 May 19.
Published in final edited form as: Nat Commun. 2014; 5: 5593. Published online 2014 Nov 19. doi: 10.1038/ncomms6593
PMCID:
PMC4238044
ArticlePDF–695K
16.
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis
Stephan Weidinger, Saffron A.G. Willis-Owen, Yoichiro Kamatani, Hansjörg Baurecht, Nilesh Morar, Liming Liang, Pauline Edser, Teresa Street, Elke Rodriguez, Grainne M. O'Regan, Paula Beattie, Regina Fölster-Holst, Andre Franke, Natalija Novak, Caoimhe M. Fahy, Mårten C.G. Winge, Michael Kabesch, Thomas Illig, Simon Heath, Cilla Söderhäll, Erik Melén, Göran Pershagen, Juha Kere, Maria Bradley, Agne Lieden, Magnus Nordenskjold, John I. Harper, W.H. Irwin Mclean, Sara J. Brown, William O.C. Cookson, G. Mark Lathrop, Alan D. Irvine, Miriam F. Moffatt
Hum Mol Genet. 2013 Dec 1; 22(23): 4841–4856. Published online 2013 Jul 25. doi: 10.1093/hmg/ddt317
PMCID:
PMC3820131
ArticlePDF–898K
17.
Identification and Characterization of a Novel Nuclear Protein Complex Involved in Nuclear Hormone Receptor-mediated Gene Regulation
Shivani Garapaty, Chong-Feng Xu, Patrick Trojer, Muktar A. Mahajan, Thomas A. Neubert, Herbert H. Samuels
J Biol Chem. 2009 Mar 20; 284(12): 7542–7552. doi: 10.1074/jbc.M805872200
PMCID:
PMC2658049
ArticlePDF–531K
18.
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease
Leah C. Kottyan, Benjamin P. Davis, Joseph D. Sherrill, Kan Liu, Mark Rochman, Kenneth Kaufman, Matthew T. Weirauch, Samuel Vaughn, Sara Lazaro, Andrew M. Rupert, Mojtaba Kohram, Emily M. Stucke, Katherine A. Kemme, Albert Magnusen, Hua He, Phillip Dexheimer, Mirna Chehade, Robert A. Wood, Robbie D. Pesek, Brian P. Vickery, David M. Fleischer, Robert Lindbad, Hugh A. Sampson, Vince Mukkada, Phil E. Putnam, J. Pablo Abonia, Lisa J. Martin, John B. Harley, Marc E. Rothenberg
Nat Genet. Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: Nat Genet. 2014 Aug; 46(8): 895–900. Published online 2014 Jul 13. doi: 10.1038/ng.3033
PMCID:
PMC4121957
ArticlePDF–832K
19.
Genome-wide association defines more than thirty distinct susceptibility loci for Crohn's disease
Jeffrey C. Barrett, Sarah Hansoul, Dan L. Nicolae, Judy H. Cho, Richard H. Duerr, John D. Rioux, Steven R. Brant, Mark S. Silverberg, Kent D. Taylor, M. Michael Barmada, Alain Bitton, Themistocles Dassopoulos, Lisa Wu Datta, Todd Green, Anne M. Griffiths, Emily O. Kistner, Michael T. Murtha, Miguel D. Regueiro, Jerome I. Rotter, L. Philip Schumm, A. Hillary Steinhart, Stephan R. Targan, Ramnik J. Xavier, the NIDDK IBD Genetics Consortium, Cécile Libioulle, Cynthia Sandor, Mark Lathrop, Jacques Belaiche, Olivier Dewit, Ivo Gut, Simon Heath, Debby Laukens, Myriam Mni, Paul Rutgeerts, André Van Gossum, Diana Zelenika, Denis Franchimont, JP Hugot, Martine de Vos, Severine Vermeire, Edouard Louis, the Belgian-French IBD consortium, the Wellcome Trust Case Control Consortium, Lon R. Cardon, Carl A. Anderson, Hazel Drummond, Elaine Nimmo, Tariq Ahmad, Natalie J Prescott, Clive M. Onnie, Sheila A. Fisher, Jonathan Marchini, Jilur Ghori, Suzannah Bumpstead, Rhian Gwillam, Mark Tremelling, Panos Deloukas, John Mansfield, Derek Jewell, Jack Satsangi, Christopher G. Mathew, Miles Parkes, Michel Georges, Mark J. Daly
Nat Genet. Author manuscript; available in PMC 2009 May 1.
Published in final edited form as: Nat Genet. 2008 Aug; 40(8): 955–962. Published online 2008 Jun 29. doi: 10.1038/NG.175
PMCID:
PMC2574810
ArticlePDF–575K
20.
Evidence for Significant Overlap between Common Risk Variants for Crohn's Disease and Ankylosing Spondylitis
Debby Laukens, Michel Georges, Cécile Libioulle, Cynthia Sandor, Myriam Mni, Bert Vander Cruyssen, Harald Peeters, Dirk Elewaut, Martine De Vos
PLoS One. 2010; 5(11): e13795. Published online 2010 Nov 2. doi: 10.1371/journal.pone.0013795
PMCID:
PMC2970560
ArticlePDF–178K

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