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Select item 93033851.

Mitochondrial RNA processing defect caused by a SUPV3L1 mutation in two siblings with a novel neurodegenerative syndrome

Selma L. van Esveld, Richard J. Rodenburg, Fathiya Al‐Murshedi, Eiman Al‐Ajmi, Sana Al‐Zuhaibi, Martijn A. Huynen, Johannes N. Spelbrink

J Inherit Metab Dis. 2022 Mar; 45(2): 292–307. Published online 2022 Jan 21. doi: 10.1002/jimd.12476

PMCID:: PMC9303385

Article PDF–4.5M

Select item 90444072.

Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay

Monika Jain, Bagher Golzarroshan, Chia‐Liang Lin, Sashank Agrawal, Wei‐Hsuan Tang, Chiu‐Ju Wu, Hanna S. Yuan

Protein Sci. 2022 May; 31(5): e4312. Published online 2022 Apr 27. doi: 10.1002/pro.4312

PMCID:: PMC9044407

Article PDF–16M

Select item 55826163.

Regulation of the human Suv3 helicase on DNA by inorganic cofactors

Susanne T. Venø, Marie B. Witt, Tomasz Kulikowicz, Vilhelm A. Bohr, Tinna Stevnsner

Biochimie. Author manuscript; available in PMC 2017 Sep 4.

Published in final edited form as: Biochimie. 2015 Jan; 108: 160–168. Published online 2014 Nov 21. doi: 10.1016/j.biochi.2014.11.003

PMCID:: PMC5582616

Article PDF–623K

Select item 40591174.

Helicase SUV3, Polynucleotide Phosphorylase, and Mitochondrial Polyadenylation Polymerase Form a Transient Complex to Modulate Mitochondrial mRNA Polyadenylated Tail Lengths in Response to Energetic Changes

Dennis Ding-Hwa Wang, Xuning Emily Guo, Aram Sandaldjian Modrek, Chi-Fen Chen, Phang-Lang Chen, Wen-Hwa Lee

J Biol Chem. 2014 Jun 13; 289(24): 16727–16735. Published online 2014 Apr 25. doi: 10.1074/jbc.M113.536540

PMCID:: PMC4059117

Article PDF–956K

Select item 70689725.

Identification of immune cells and mRNA associated with prognosis of gastric cancer

Mingming Wang, Zedong Li, Yu Peng, Jianyu Fang, Tao Fang, Jiajia Wu, Jun Zhou

BMC Cancer. 2020; 20: 206. Published online 2020 Mar 12. doi: 10.1186/s12885-020-6702-1

PMCID:: PMC7068972

Article PDF–3.7M

Select item 35539516.

Human mitochondrial RNA decay mediated by PNPase–hSuv3 complex takes place in distinct foci

Lukasz S. Borowski, Andrzej Dziembowski, Monika S. Hejnowicz, Piotr P. Stepien, Roman J. Szczesny

Nucleic Acids Res. 2013 Jan; 41(2): 1223–1240. Published online 2012 Dec 5. doi: 10.1093/nar/gks1130

PMCID:: PMC3553951

Article PDF–13M

Select item 25560027.

Role of SUV3 Helicase in Maintaining Mitochondrial Homeostasis in Human Cells

Lily Khidr, Guikai Wu, Antonio Davila, Vincent Procaccio, Douglas Wallace, Wen-Hwa Lee

J Biol Chem. 2008 Oct 3; 283(40): 27064–27073. doi: 10.1074/jbc.M802991200

PMCID:: PMC2556002

Article PDF–607K

Select item 1379618.

Localisation of the human hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA

Michal Minczuk, Jan Piwowarski, Monika A. Papworth, Karen Awiszus, Sarah Schalinski, Andrzej Dziembowski, Aleksandra Dmochowska, Ewa Bartnik, Kostas Tokatlidis, Piotr P. Stepien, Peter Borowski

Nucleic Acids Res. 2002 Dec 1; 30(23): 5074–5086. doi: 10.1093/nar/gkf647

PMCID:: PMC137961

Article PDF–326K

Select item 28002379.

Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance

Roman J. Szczesny, Lukasz S. Borowski, Lien K. Brzezniak, Aleksandra Dmochowska, Kamil Gewartowski, Ewa Bartnik, Piotr P. Stepien

Nucleic Acids Res. 2010 Jan; 38(1): 279–298. Published online 2009 Oct 28. doi: 10.1093/nar/gkp903

PMCID:: PMC2800237

Article PDF–1.8M

Select item 274284610.

Human Mitochondrial SUV3 and Polynucleotide Phosphorylase Form a 330-kDa Heteropentamer to Cooperatively Degrade Double-stranded RNA with a 3′-to-5′ Directionality

Dennis Ding-Hwa Wang, Zhanyong Shu, Scot A. Lieser, Phang-Lang Chen, Wen-Hwa Lee

J Biol Chem. 2009 Jul 31; 284(31): 20812–20821. Published online 2009 Jun 9. doi: 10.1074/jbc.M109.009605

PMCID:: PMC2742846

Article PDF–1.9M

Select item 602838911.

Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria

Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny

Nat Commun. 2018; 9: 2558. Published online 2018 Jul 2. doi: 10.1038/s41467-018-05007-9

PMCID:: PMC6028389

Article PDF–3.3M

Select item 374932612.

Identification of HKDC1 and BACE2 as Genes Influencing Glycemic Traits During Pregnancy Through Genome-Wide Association Studies

M. Geoffrey Hayes, Margrit Urbanek, Marie-France Hivert, Loren L. Armstrong, Jean Morrison, Cong Guo, Lynn P. Lowe, Douglas A. Scheftner, Anna Pluzhnikov, David M. Levine, Caitlin P. McHugh, Christine M. Ackerman, Luigi Bouchard, Diane Brisson, Brian T. Layden, Daniel Mirel, Kimberly F. Doheny, Marysa V. Leya, Rachel N. Lown-Hecht, Alan R. Dyer, Boyd E. Metzger, Timothy E. Reddy, Nancy J. Cox, William L. Lowe, Jr., for the HAPO Study Cooperative Research Group

Diabetes. 2013 Sep; 62(9): 3282–3291. Published online 2013 Aug 15. doi: 10.2337/db12-1692

Correction in:: Diabetes. 2013 Oct; 62(10): 3641.

PMCID:: PMC3749326

Article PDF–1.0M

Select item 417058513.

Genome-Wide Analysis of Polymorphisms Associated with Cytokine Responses in Smallpox Vaccine Recipients

Richard B. Kennedy, Inna G. Ovsyannikova, V. Shane Pankratz, Iana H. Haralambieva, Robert A. Vierkant, Gregory A. Poland

Hum Genet. Author manuscript; available in PMC 2014 Sep 22.

Published in final edited form as: Hum Genet. 2012 Sep; 131(9): 1403–1421. Published online 2012 May 19. doi: 10.1007/s00439-012-1174-2

PMCID:: PMC4170585

Article PDF–594K

Select item 711512814.

Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan

Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam

Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525

PMCID:: PMC7115128

Article PDF–1.6M

Select item 662002815.

Mitochondrial ClpP-mediated proteolysis induces selective cancer cell lethality

Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis, Ondrej Halgas, Takenobu Nii, Yulia Jitkova, Ran Zhao, Jonathan St-Germain, Lauren E. Heese, Grace Egan, Vivian R. Ruvolo, Samir H. Barghout, Yuki Nishida, Rose Hurren, Wencai Ma, Marcela Gronda, Todd Link, Keith Wong, Mark Mabanglo, Kensuke Kojima, Gautam Borthakur, Neil MacLean, John Man Chun Ma, Andrew B. Leber, Mark D. Minden, Walid Houry, Hagop Kantarjian, Martin Stogniew, Brian Raught, Emil F. Pai, Aaron D. Schimmer, Michael Andreeff

Cancer Cell. Author manuscript; available in PMC 2020 May 13.

Published in final edited form as: Cancer Cell. 2019 May 13; 35(5): 721–737.e9. Published online 2019 May 2. doi: 10.1016/j.ccell.2019.03.014

PMCID:: PMC6620028

Article PDF–2.9M

Select item 284527116.

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

Ricarda Richter, Joanna Rorbach, Aleksandra Pajak, Paul M Smith, Hans J Wessels, Martijn A Huynen, Jan A Smeitink, Robert N Lightowlers, Zofia M Chrzanowska-Lightowlers

EMBO J. 2010 Mar 17; 29(6): 1116–1125. Published online 2010 Feb 25. doi: 10.1038/emboj.2010.14

PMCID:: PMC2845271

Article PDF–1.3M

Select item 138022517.

A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease

Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate

Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851

PMCID:: PMC1380225

Article PDF–329K

Select item 760600818.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Article PDF–2.5M

Select item 875541919.

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation

Yuzheng Zhou, Rong Zheng, Sixu Liu, Cyrollah Disoma, Ashuai Du, Shiqin Li, Zongpeng Chen, Zijun Dong, Yongxing Zhang, Sijia Li, Pinjia Liu, Aroona Razzaq, Xuan Chen, Yujie Liao, Siyi Tao, Yuxin Liu, Lunan Xu, Qianjun Zhang, Jian Peng, Xu Deng, Shanni Li, Taijiao Jiang, Zanxian Xia

J Biol Chem. 2022 Feb; 298(2): 101584. Published online 2022 Jan 13. doi: 10.1016/j.jbc.2022.101584

PMCID:: PMC8755419

Article PDF–3.5M

Select item 289232020.

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice

David Llères, Marco Denegri, Marco Biggiogera, Paul Ajuh, Angus I Lamond

EMBO Rep. 2010 Jun; 11(6): 445–451. Published online 2010 May 14. doi: 10.1038/embor.2010.64

PMCID:: PMC2892320

Article PDF–895K

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