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Select item 28178521.

High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand

Robert Cheng, Brunella Felicetti, Shilpa Palan, Ian Toogood-Johnson, Christoph Scheich, John Barker, Mark Whittaker, Thomas Hesterkamp

Protein Sci. 2010 Jan; 19(1): 168–173. Published online 2009 Nov 20. doi: 10.1002/pro.294

PMCID:: PMC2817852

Article PDF–234K

Select item 2316712.

3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways.

S Ludwig, K Engel, A Hoffmeyer, G Sithanandam, B Neufeld, D Palm, M Gaestel, U R Rapp

Mol Cell Biol. 1996 Dec; 16(12): 6687–6697. doi: 10.1128/mcb.16.12.6687

PMCID:: PMC231671

Summary PDF–841K

Select item 2310673.

3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region.

G Sithanandam, F Latif, F M Duh, R Bernal, U Smola, H Li, I Kuzmin, V Wixler, L Geil, S Shrestha

Mol Cell Biol. 1996 Mar; 16(3): 868–876. doi: 10.1128/mcb.16.3.868

PMCID:: PMC231067

Summary PDF–450K

Select item 43902454.

MK3 Modulation Affects BMI1-Dependent and Independent Cell Cycle Check-Points

Peggy Prickaerts, Hanneke E. C. Niessen, Vivian E. H. Dahlmans, Frank Spaapen, Juliette Salvaing, Jolien Vanhove, Claudia Geijselaers, Stefanie J. J. Bartels, Iris Partouns, Dietbert Neumann, Ernst-Jan Speel, Yoshihiro Takihara, Bradly G. Wouters, Jan Willem Voncken

PLoS One. 2015; 10(4): e0118840. Published online 2015 Apr 8. doi: 10.1371/journal.pone.0118840

PMCID:: PMC4390245

Article PDF–9.3M

Select item 36481695.

Modulation of Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 by Hepatitis C Virus Core Protein

Huong T. T. Ngo, Long V. Pham, Jong-Wook Kim, Yun-Sook Lim, Soon B. Hwang

J Virol. 2013 May; 87(10): 5718–5731. doi: 10.1128/JVI.03353-12

PMCID:: PMC3648169

Article PDF–2.3M

Select item 31177536.

Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38^MAPK-induced heat shock protein 27 phosphorylation

Alexey Shiryaev, Gianina Dumitriu, Ugo Moens

J Mol Signal. 2011; 6: 4. Published online 2011 May 16. doi: 10.1186/1750-2187-6-4

PMCID:: PMC3117753

Article PDF–770K

Select item 3947117.

Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2.

R Ben-Levy, I A Leighton, Y N Doza, P Attwood, N Morrice, C J Marshall, P Cohen

EMBO J. 1995 Dec 1; 14(23): 5920–5930. doi: 10.1002/j.1460-2075.1995.tb00280.x

PMCID:: PMC394711

Article PDF–2.1M

Select item 2320018.

Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27.

J N Lavoie, H Lambert, E Hickey, L A Weber, J Landry

Mol Cell Biol. 1995 Jan; 15(1): 505–516. doi: 10.1128/mcb.15.1.505

PMCID:: PMC232001

Summary PDF–1.7M

Select item 43377289.

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

Yongjie Wei, Zhenyi An, Zhongju Zou, Rhea Sumpter, Jr, Minfei Su, Xiao Zang, Sangita Sinha, Matthias Gaestel, Beth Levine

eLife. 2015; 4: e05289. Published online 2015 Feb 18. doi: 10.7554/eLife.05289

PMCID:: PMC4337728

Article PDF–5.7M

Select item 13346110.

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions

Takuji Tanoue, Ryota Maeda, Makoto Adachi, Eisuke Nishida

EMBO J. 2001 Feb 1; 20(3): 466–479. doi: 10.1093/emboj/20.3.466

PMCID:: PMC133461

Article PDF–529K

Select item 678721011.

Long noncoding RNA LINC02582 acts downstream of miR-200c to promote radioresistance through CHK1 in breast cancer cells

Baiyao Wang, Jieling Zheng, Rong Li, Yunhong Tian, Jie Lin, Yingying Liang, Quanquan Sun, Anan Xu, Ronghui Zheng, Mengzhong Liu, Aimin Ji, Junguo Bu, Yawei Yuan

Cell Death Dis. 2019 Oct; 10(10): 764. Published online 2019 Oct 10. doi: 10.1038/s41419-019-1996-0

PMCID:: PMC6787210

Article PDF–3.1M

Select item 122291012.

Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways.

Axel Knebel, Claire E Haydon, Nick Morrice, Philip Cohen

Biochem J. 2002 Oct 15; 367(Pt 2): 525–532. doi: 10.1042/BJ20020916

PMCID:: PMC1222910

Summary PDF–308K

Select item 118454513.

The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ

Claire E. Eyers, Helen McNeill, Axel Knebel, Nick Morrice, Simon J. C. Arthur, Ana Cuenda, Philip Cohen

Biochem J. 2005 Jul 1; 389(Pt 1): 127–135. Prepublished online 2005 Apr 26. Published online 2005 Jun 21. doi: 10.1042/BJ20050387

PMCID:: PMC1184545

Article PDF–489K

Select item 282448814.

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays

Avinash Persaud, Philipp Alberts, Eva M Amsen, Xuejian Xiong, James Wasmuth, Zachary Saadon, Chris Fladd, John Parkinson, Daniela Rotin

Mol Syst Biol. 2009; 5: 333. Published online 2009 Dec 1. doi: 10.1038/msb.2009.85

PMCID:: PMC2824488

Article PDF–3.1M

Select item 433215015.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Article PDF–2.8M

Select item 501331516.

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family

Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang

Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277

PMCID:: PMC5013315

Article PDF–3.2M

Select item 674264617.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Article PDF–1.2M

Select item 464794118.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Article

Select item 698120619.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Article PDF–3.7M

Select item 319082620.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Article PDF–5.7M

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