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Select item 58509161.

Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1

Sheng Liu, Josephine Iaria, Richard J. Simpson, Hong-Jian Zhu

Cell Commun Signal. 2018; 16: 10. Published online 2018 Mar 13. doi: 10.1186/s12964-018-0223-4

PMCID:: PMC5850916

Article PDF–3.8M

Select item 53856212.

SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling

Feng Wang, Xing Fu, Peng Chen, Ping Wu, Xiaojuan Fan, Na Li, Hong Zhu, Ting-Ting Jia, Hongbin Ji, Zefeng Wang, Catherine C L Wong, Ronggui Hu, Jingyi Hui

Cell Res. 2017 Apr; 27(4): 540–558. Published online 2017 Jan 13. doi: 10.1038/cr.2017.7

PMCID:: PMC5385621

Article PDF–7.4M

Select item 79535923.

The E3 ligases Spsb1 and Spsb4 regulate RevErbα degradation and circadian period.

Tsedey Mekbib, Ting-Chung Suen, Aisha Rollins-Hairston, Jason P. DeBruyne

J Biol Rhythms. Author manuscript; available in PMC 2021 Mar 12.

Published in final edited form as: J Biol Rhythms. 2019 Dec; 34(6): 610–621. Published online 2019 Oct 14. doi: 10.1177/0748730419878036

PMCID:: PMC7953592

Article PDF–1.1M

Select item 69853654.

Cullin-5 Adaptor SPSB1 Controls NF-κB Activation Downstream of Multiple Signaling Pathways

Iliana Georgana, Carlos Maluquer de Motes

Front Immunol. 2019; 10: 3121. Published online 2020 Jan 21. doi: 10.3389/fimmu.2019.03121

PMCID:: PMC6985365

Article PDF–5.2M

Select item 41217385.

SPSB1 Promotes Breast Cancer Recurrence by Potentiating c-MET Signaling

Yi Feng, Tien-Chi Pan, Dhruv K. Pant, Kristi R. Chakrabarti, James V. Alvarez, Jason R. Ruth, Lewis A. Chodosh

Cancer Discov. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Cancer Discov. 2014 Jul; 4(7): 790–803. Published online 2014 Apr 30. doi: 10.1158/2159-8290.CD-13-0548

PMCID:: PMC4121738

Article PDF–1.5M

Select item 45050386.

SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor

Sheng Liu, Thao Nheu, Rodney Luwor, Sandra E. Nicholson, Hong-Jian Zhu

J Biol Chem. 2015 Jul 17; 290(29): 17894–17908. Published online 2015 Jun 1. doi: 10.1074/jbc.M114.607184

PMCID:: PMC4505038

Article PDF–2.4M

Select item 73114677.

SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites

Liwen Zhou, Lisi Zheng, Kaishun Hu, Xin Wang, Ruhua Zhang, Yezi Zou, Li Zhong, Shang Wang, Yuanzhong Wu, Tiebang Kang

Signal Transduct Target Ther. 2020; 5: 80. Published online 2020 Jun 24. doi: 10.1038/s41392-020-0172-4

PMCID:: PMC7311467

Article PDF–3.9M

Select item 44464298.

RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling

Ananya Kar, Manpreet Kaur, Tanushree Ghosh, Md. Muntaz Khan, Aparna Sharma, Ritu Shekhar, Akhil Varshney, Sandeep Saxena

Nucleic Acids Res. 2015 May 26; 43(10): 4962–4974. Published online 2015 Apr 27. doi: 10.1093/nar/gkv369

PMCID:: PMC4446429

Article PDF–9.4M

Select item 41596229.

PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis

Hanqiu Zheng, Minhong Shen, Yin-Lian Cha, Wenyang Li, Yong Wei, Mario Andres Blanco, Guangwen Ren, Tianhua Zhou, Peter Storz, Hui-Yun Wang, Yibin Kang

Cancer Cell. Author manuscript; available in PMC 2015 Sep 8.

Published in final edited form as: Cancer Cell. 2014 Sep 8; 26(3): 358–373. doi: 10.1016/j.ccr.2014.07.022

PMCID:: PMC4159622

Article PDF–3.2M

Select item 568376310.

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2

Fumihiko Okumura, Akiko Joo-Okumura, Keisuke Obara, Alexander Petersen, Akihiko Nishikimi, Yoshinori Fukui, Kunio Nakatsukasa, Takumi Kamura

Mol Biol Cell. 2017 Nov 15; 28(24): 3532–3541. doi: 10.1091/mbc.E17-07-0450

PMCID:: PMC5683763

Article PDF–2.5M

Select item 305898911.

Regulation of Inducible Nitric-oxide Synthase by the SPRY Domain- and SOCS Box-containing Proteins

Tadashi Nishiya, Kazuma Matsumoto, Satoshi Maekawa, Emi Kajita, Takahiro Horinouchi, Masahiro Fujimuro, Kouetsu Ogasawara, Takashi Uehara, Soichi Miwa

J Biol Chem. 2011 Mar 18; 286(11): 9009–9019. Published online 2011 Jan 3. doi: 10.1074/jbc.M110.190678

PMCID:: PMC3058989

Article PDF–3.1M

Select item 291166512.

The SPRY domain–containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

Zhihe Kuang, Rowena S. Lewis, Joan M. Curtis, Yifan Zhan, Bernadette M. Saunders, Jeffrey J. Babon, Tatiana B. Kolesnik, Andrew Low, Seth L. Masters, Tracy A. Willson, Lukasz Kedzierski, Shenggen Yao, Emanuela Handman, Raymond S. Norton, Sandra E. Nicholson

J Cell Biol. 2010 Jul 12; 190(1): 129–141. doi: 10.1083/jcb.200912087

PMCID:: PMC2911665

Article PDF–4.2M

Select item 292377813.

Structural Basis for Par-4 Recognition by the SPRY Domain- and SOCS Box-Containing Proteins SPSB1, SPSB2, and SPSB4

Panagis Filippakopoulos, Andrew Low, Timothy D. Sharpe, Jonas Uppenberg, Shenggen Yao, Zhihe Kuang, Pavel Savitsky, Rowena S. Lewis, Sandra E. Nicholson, Raymond S. Norton, Alex N. Bullock

J Mol Biol. 2010 Aug 20; 401(3-2): 389–402. doi: 10.1016/j.jmb.2010.06.017

PMCID:: PMC2923778

Article

Select item 338774814.

A Genome-wide Association Study of Host Genetic Determinants of the Antibody Response to Anthrax Vaccine Adsorbed

Nicholas M. Pajewski, Sadeep Shrestha, Conrad P. Quinn, Scott D. Parker, Howard Wiener, Brahim Aissani, Brett A. McKinney, Gregory A. Poland, Jeffrey C. Edberg, Robert P. Kimberly, Jianming Tang, Richard A. Kaslow

Vaccine. Author manuscript; available in PMC 2013 Jul 6.

Published in final edited form as: Vaccine. 2012 Jul 6; 30(32): 4778–4784. Published online 2012 May 31. doi: 10.1016/j.vaccine.2012.05.032