PMC Articles for PubChem Compound (Select 65411) - PMC

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Items: 10

Select item 112658361.

Triptonide protects retinal cells from oxidative damage via activation of Nrf2 signaling

Jinjing Li, Jiajun Li, Yuan Cao, Jin Yuan, Yaming Shen, Linyi Lei, Keran Li

Int J Mol Med. 2024 Sep; 54(3): 76. Published online 2024 Jul 8. doi: 10.3892/ijmm.2024.5400

PMCID:: PMC11265836

Article PDF–14M

Select item 98308342.

Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns

Meng Li, Qiong Luo, Xi Chen, Furong Qiu, Yanyan Tao, Xin Sun, Chenghai Liu

BMC Complement Med Ther. 2023; 23: 9. Published online 2023 Jan 10. doi: 10.1186/s12906-023-03836-w

PMCID:: PMC9830834

Article PDF–2.0M

Select item 94112043.

Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide

Nikolaj Lervad Hansen, Louise Kjaerulff, Quinn Kalby Heck, Victor Forman, Dan Staerk, Birger Lindberg Møller, Johan Andersen-Ranberg

Nat Commun. 2022; 13: 5011. Published online 2022 Aug 25. doi: 10.1038/s41467-022-32667-5

PMCID:: PMC9411204

Article PDF–1011K

Select item 86841434.

Triptonide effectively inhibits triple-negative breast cancer metastasis through concurrent degradation of Twist1 and Notch1 oncoproteins

Mengli Zhang, Mei Meng, Yuxi Liu, Jindan Qi, Zhe Zhao, Yingnan Qiao, Yanxing Hu, Wei Lu, Zhou Zhou, Peng Xu, Quansheng Zhou

Breast Cancer Res. 2021; 23: 116. Published online 2021 Dec 18. doi: 10.1186/s13058-021-01488-7

PMCID:: PMC8684143

Article PDF–2.4M

Select item 85997775.

A plant root extract, triptonide, is a reversible male contraceptive in mice and monkeys

Erv Goldberg

Biol Reprod. 2021 Jun; 104(6): 1187–1188. Published online 2021 Mar 23. doi: 10.1093/biolre/ioab057

PMCID:: PMC8599777

Article PDF–202K

Select item 79026136.

Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates

Zongliang Chang, Weibing Qin, Huili Zheng, Kathleen Schegg, Lu Han, Xiaohua Liu, Yue Wang, Zhuqing Wang, Hayden McSwiggin, Hongying Peng, Shuiqiao Yuan, Jiabao Wu, Yongxia Wang, Shenghui Zhu, Yanjia Jiang, Hua Nie, Yuan Tang, Yu Zhou, Michael J. M. Hitchcock, Yunge Tang, Wei Yan

Nat Commun. 2021; 12: 1253. Published online 2021 Feb 23. doi: 10.1038/s41467-021-21517-5

PMCID:: PMC7902613

Article PDF–2.5M

Select item 78435987.

Identification of triptonide as a therapeutic agent for triple negative breast cancer treatment

Bowen Gao, Jiongyu Chen, Bingchen Han, Xinfeng Zhang, Jijun Hao, Armando E. Giuliano, Yukun Cui, Xiaojiang Cui

Sci Rep. 2021; 11: 2408. Published online 2021 Jan 28. doi: 10.1038/s41598-021-82128-0

PMCID:: PMC7843598

Article PDF–1.8M

Select item 73702248.

The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy

Bo Yang, Bin Zhang, Zhifei Cao, Xingdong Xu, Zihe Huo, Pan Zhang, Shufen Xiang, Zhe Zhao, Chunping Lv, Mei Meng, Gaochuan Zhang, Liang Dong, Shucheng Shi, Lan Yang, Quansheng Zhou

Cell Death Differ. 2020 Aug; 27(8): 2433–2450. Published online 2020 Mar 6. doi: 10.1038/s41418-020-0514-3