Ventricular cardiomyocytes generated in vitro from embryonic stem cells
Summary:
Analysis of ventricular cardiomyocytes derived from HES2 embryonic stem cells (hESC-VCMs). The in vivo counterparts (undifferentiated HES2 cells, fetal VCMs, and adult VCMs) were also examined. Results provide insight into molecular mechanisms underlying the developmental status of hESC-VCMs.
Poon E, Yan B, Zhang S, Rushing S et al. Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes crucial for maturation. PLoS One 2013;8(10):e77784. PMID: 24204964
