show Abstracthide AbstractWe report here the draft genome sequence of Streptomyces sp. Strain AM-2504, a widely studied strain producing a large range of biotechnologically-relevant molecules. The comparative analysis of its 16S rRNA sequence allowed the assignment of this Streptomyces strain to the Kasugaensis species, thus fostering an improved biochemical and functional characterization of its antibiotic products, through evolutionary comparative analyses.