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    itgb4 integrin, beta 4 [ Poecilia mexicana ]

    Gene ID: 106905455, updated on 13-Mar-2024

    Summary

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    Gene symbol
    itgb4
    Gene description
    integrin, beta 4
    See related
    Ensembl:ENSPMEG00000023256
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Poecilia mexicana
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
    Orthologs
    human zebrafish all
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    Genomic context

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    See itgb4 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    46
    Annotation release Status Assembly Chr Location
    100 current P_mexicana-1.0 (GCF_001443325.1) Unplaced Scaffold NW_015096654.1 (36922..64482, complement)

    NW_015096654.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106905459 Neighboring gene H3 histone, family 3B Neighboring gene uncharacterized LOC106905457 Neighboring gene uncharacterized LOC106905464 Neighboring gene SAP30 binding protein Neighboring gene uncharacterized LOC106905466

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_015096654.1 Unplaced Scaffold Reference P_mexicana-1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell communication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin beta-4
    Names
    integrin subunit beta 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Poecilia mexicana Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference P_mexicana-1.0

    Genomic

    1. NW_015096654.1 Reference P_mexicana-1.0

      Range
      36922..64482 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014970304.1 → XP_014825790.1  integrin beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1248 → 1334
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1815 → 1900
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 458
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:629 → 714
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:469 → 491
      EGF_2; EGF-like domain
      cl02522
      Location:1000 → 1094
      Calx-beta; Calx-beta domain

    2. XM_014970305.1 → XP_014825791.1  integrin beta-4 isoform X2

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1247 → 1333
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1814 → 1899
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 457
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:628 → 713
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:468 → 490
      EGF_2; EGF-like domain
      cl02522
      Location:999 → 1093
      Calx-beta; Calx-beta domain

    3. XM_014970307.1 → XP_014825793.1  integrin beta-4 isoform X4

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1248 → 1334
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1767 → 1852
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 458
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:629 → 714
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:469 → 491
      EGF_2; EGF-like domain
      cl02522
      Location:1000 → 1094
      Calx-beta; Calx-beta domain

    4. XM_014970306.1 → XP_014825792.1  integrin beta-4 isoform X3

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1248 → 1334
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1812 → 1897
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 458
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:629 → 714
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:469 → 491
      EGF_2; EGF-like domain
      cl02522
      Location:1000 → 1094
      Calx-beta; Calx-beta domain

    5. XM_014970303.1 → XP_014825789.1  integrin beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1248 → 1334
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1815 → 1900
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 458
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:629 → 714
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:469 → 491
      EGF_2; EGF-like domain
      cl02522
      Location:1000 → 1094
      Calx-beta; Calx-beta domain

    6. XM_014970311.1 → XP_014825797.1  integrin beta-4 isoform X8

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Related
      ENSPMEP00000019781.1, ENSPMET00000029250.1
      Conserved Domains (6) summary
      cd00063
      Location:1247 → 1333
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1714 → 1799
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 457
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:628 → 713
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:468 → 490
      EGF_2; EGF-like domain
      cl02522
      Location:999 → 1093
      Calx-beta; Calx-beta domain

    7. XM_014970309.1 → XP_014825795.1  integrin beta-4 isoform X6

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1247 → 1333
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1762 → 1847
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 457
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:628 → 713
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:468 → 490
      EGF_2; EGF-like domain
      cl02522
      Location:999 → 1093
      Calx-beta; Calx-beta domain

    8. XM_014970310.1 → XP_014825796.1  integrin beta-4 isoform X7

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1248 → 1334
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1715 → 1800
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 458
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:629 → 714
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:469 → 491
      EGF_2; EGF-like domain
      cl02522
      Location:1000 → 1094
      Calx-beta; Calx-beta domain

    9. XM_014970308.1 → XP_014825794.1  integrin beta-4 isoform X5

      UniProtKB/TrEMBL
      A0A3B3XXK7
      Conserved Domains (6) summary
      cd00063
      Location:1248 → 1334
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:1763 → 1848
      fn3; Fibronectin type III domain
      pfam00362
      Location:36 → 458
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:629 → 714
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:469 → 491
      EGF_2; EGF-like domain
      cl02522
      Location:1000 → 1094
      Calx-beta; Calx-beta domain
    Nucleotide Protein
    Heading Accession and Version

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