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Status |
Public on Aug 31, 2009 |
Title |
Molecular and functional characterization of FD-iPSC derived neural crest precursor cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Global gene expression analysis of FD-iPSC and deribved neural crest cells
Here we report the derivation of patient specific Familial Dysautonomia-iPSCs and their directed differentiation into multiple cell types capable of modeling the tissue specific splicing defect in vitro.
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Overall design |
Undifferentiated hESCs were exposed to control and drug treatments for 24 hours followed by mRNA expression analysis Global gene expression analysis of FD-iPSC and derived neural crest cells
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Contributor(s) |
Lee G, Studer L |
Citation(s) |
19693009 |
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Submission date |
Jul 10, 2009 |
Last update date |
Aug 16, 2018 |
Contact name |
Agnes Viale |
E-mail(s) |
vialea@mskcc.org
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Phone |
212 639 3031
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Fax |
212 717 3053
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Organization name |
Memorial Sloan Kettering Cancer Center
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Department |
Molecular Biology
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Lab |
Genomics Core Laboratory
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Street address |
1275 York Avenue
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City |
New York |
State/province |
NY |
ZIP/Postal code |
10021 |
Country |
USA |
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Platforms (2) |
GPL6102 |
Illumina human-6 v2.0 expression beadchip |
GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
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Samples (18)
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Relations |
BioProject |
PRJNA117847 |