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| Status |
Public on Mar 27, 2012 |
| Title |
Enhanced expression of Ficolin 1 is a specific gene marker of Takayasu's vasculitis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Takayasu's arteritis (TA) Vasculitis (angiitis) is a chronic inflammatory disease involving large blood vessels. We here identify the genes whose mRNA levels are commonly augmented in the peripheral blood mononuclear cells (PBMCs) from TA patients regardless of the patient's symptom, active or inactive phase, compared with those of normal volunteers. Among them, ficolin 1 (FCN1) was notable because its mRNA level was more than 4.0 fold in all 8 patients examined.
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| Overall design |
A total of 8 two color arrays were performed and each individual array included a target sample and a control sample.
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| Contributor(s) |
Okuzaki D, Kobayashi S, Nojima H |
| Citation |
Okuzaki D, Kobayashi S, Sakurai MA, Torigata K, Okamoto A, et al.(2012) Ficolin 1 Expression is Elevated in the Peripheral Blood Mononuclear Cells of Takayasu's Vasculitis Patients. J Mol Biomark Diagn 2:125. doi:10.4172/2155-9929.1000125
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| Submission date |
Nov 23, 2011 |
| Last update date |
Feb 22, 2018 |
| Contact name |
Daisuke Okuzaki |
| E-mail(s) |
dokuzaki@biken.osaka-u.ac.jp
|
| Phone |
+81-6-6879-4935
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| Organization name |
Osaka univ.
|
| Department |
Immunology Frontier Research Center
|
| Lab |
Human Immunology （Single Cell Genomics)
|
| Street address |
Yamadaoka 3-1
|
| City |
Suita |
| State/province |
Osaka |
| ZIP/Postal code |
565-0871 |
| Country |
Japan |
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| Platforms (1) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
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| Samples (8)
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| GSM838646 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 1 |
| GSM838647 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 2 |
| GSM838648 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 3 |
| GSM838649 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 4 |
| GSM838650 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 5 |
| GSM838651 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 6 |
| GSM838652 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 7 |
| GSM838653 |
Peripheral mononuclear blood cells in patients with Takayasu's arteritis 8 |
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| Relations |
| BioProject |
PRJNA148245 |
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