|
| Status |
Public on Oct 12, 2012 |
| Title |
Suberoylanilide hydroxamic acid (SAHA) induces limited changes in the transcriptome of primary CD4+ T cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
This study evaluated primary CD4+ T cell gene expression treated with pharmacologically achievable concentration (340 nM) of SAHA for 24 hours in order to evaluate potential side effects of this compound in cells relevant to HIV infection.
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| |
|
| Overall design |
Analysis of human primary CD4+ T cells taken from 9 healthy donors treated with 340 nM of SAHA for 24 hours. Results identify genes modulated by SAHA treatment in human primary CD4+ T cells.
|
| |
|
| Contributor(s) |
Beliakova-Bethell N, Woelk C |
| Citation(s) |
23221426 |
| |
| Submission date |
Oct 11, 2012 |
| Last update date |
Aug 16, 2018 |
| Contact name |
Nadejda S. Beliakova-Bethell |
| E-mail(s) |
nbeliako@ucsd.edu
|
| Organization name |
University of California, San Diego
|
| Department |
Medicine
|
| Street address |
9500 Gilman Dr.
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92093 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
|
| Samples (18)
|
|
| Relations |
| BioProject |
PRJNA177331 |
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