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Metastatic Urethral Carcinoma

MedGen UID:
1654675
•Concept ID:
C4727596
•
Neoplastic Process
Synonyms: Metastatic Carcinoma of the Urethra; Metastatic Carcinoma of Urethra

Definition

A urethral carcinoma that has spread to another anatomical site. [from NCI]

Professional guidelines

PubMed

An assessment of urethral radiation exposure in the treatment of endometrial and rectal cancers.
Hines K, Nieto K, Dezarn W, Greven K, Krol B, Matthews C, Parker-Autry C
Int Urogynecol J 2023 Apr;34(4):929-935. Epub 2022 Oct 1 doi: 10.1007/s00192-022-05363-7. PMID: 36181547Free PMC Article
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Incontinence after radical prostatectomy: pathophysiology and management.
MacDiarmid SA
Curr Urol Rep 2001 Jun;2(3):209-13. doi: 10.1007/s11934-001-0080-2. PMID: 12084266

Recent clinical studies

Etiology

Radiotherapy in Metastatic Urothelial Carcinoma: Rationale and Clinical Applications.
Vassiliou V, Katsila T, Sodergren SC, Kardamakis D
Anticancer Res 2022 Aug;42(8):3767-3778. doi: 10.21873/anticanres.15867. PMID: 35896266
Ureteral involvement by metastatic malignant disease.
Hu J, Deng J, Guo J, Fu B
Clin Exp Metastasis 2019 Dec;36(6):499-509. Epub 2019 Aug 24 doi: 10.1007/s10585-019-09989-8. PMID: 31446521
Primary and secondary malignant involvement of gynaecological organs at radical cystectomy for bladder cancer: review of literature and retrospective analysis of 360 cases.
Salem H, El-Mazny A
J Obstet Gynaecol 2012 Aug;32(6):590-3. doi: 10.3109/01443615.2012.693980. PMID: 22779969
Optimizing radical prostatectomy for the early recovery of urinary continence.
Dev HS, Sooriakumaran P, Srivastava A, Tewari AK
Nat Rev Urol 2012 Jan 24;9(4):189-95. doi: 10.1038/nrurol.2012.2. PMID: 22270136
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Diagnosis

Follow-up Management of Cystectomy Patients.
Reddy M, Kader K
Urol Clin North Am 2018 May;45(2):241-247. doi: 10.1016/j.ucl.2018.01.001. PMID: 29650139
Diffuse large B-cell lymphoma of the prostate.
Warrick JI, Owens SR, Tomlins SA
Arch Pathol Lab Med 2014 Oct;138(10):1286-9. doi: 10.5858/arpa.2014-0276-CC. PMID: 25268190
Bladder cancer.
Soloway MS
Urology 1996 Oct;48(4):631. doi: 10.1016/S0090-4295(96)00328-7. PMID: 8886073
Prepubertal vulvovaginopathies.
Pokorny SF
Obstet Gynecol Clin North Am 1992 Mar;19(1):39-58. PMID: 1584544
Metastatic urethral obstruction.
Selikowitz SM, Olsson CA
Arch Surg 1973 Dec;107(6):906-8. doi: 10.1001/archsurg.1973.01350240070020. PMID: 4751838

Therapy

Granular cell tumors of the urethra.
Evmorfopoulos K, Tzortzis V, Vlachostergios PJ
Cancer Treat Res Commun 2023;35:100695. Epub 2023 Mar 17 doi: 10.1016/j.ctarc.2023.100695. PMID: 36940531
A Comprehensive Review of US FDA-Approved Immune Checkpoint Inhibitors in Urothelial Carcinoma.
Hsu FS, Su CH, Huang KH
J Immunol Res 2017;2017:6940546. Epub 2017 Dec 10 doi: 10.1155/2017/6940546. PMID: 29376081Free PMC Article
Optimizing radical prostatectomy for the early recovery of urinary continence.
Dev HS, Sooriakumaran P, Srivastava A, Tewari AK
Nat Rev Urol 2012 Jan 24;9(4):189-95. doi: 10.1038/nrurol.2012.2. PMID: 22270136
Bladder cancer: current management and opportunities for a personalized approach.
Galsky MD, Hall SJ
Mt Sinai J Med 2010 Nov-Dec;77(6):587-96. doi: 10.1002/msj.20224. PMID: 21105122
Incontinence after radical prostatectomy: pathophysiology and management.
MacDiarmid SA
Curr Urol Rep 2001 Jun;2(3):209-13. doi: 10.1007/s11934-001-0080-2. PMID: 12084266

Prognosis

Radiotherapy in Metastatic Urothelial Carcinoma: Rationale and Clinical Applications.
Vassiliou V, Katsila T, Sodergren SC, Kardamakis D
Anticancer Res 2022 Aug;42(8):3767-3778. doi: 10.21873/anticanres.15867. PMID: 35896266
Ureteral involvement by metastatic malignant disease.
Hu J, Deng J, Guo J, Fu B
Clin Exp Metastasis 2019 Dec;36(6):499-509. Epub 2019 Aug 24 doi: 10.1007/s10585-019-09989-8. PMID: 31446521
Bladder cancer: current management and opportunities for a personalized approach.
Galsky MD, Hall SJ
Mt Sinai J Med 2010 Nov-Dec;77(6):587-96. doi: 10.1002/msj.20224. PMID: 21105122
Palliation of male genital cancers.
Shukla CJ, Shabbir M, Feneley MR, Withey S, Muneer A, Minhas S
Clin Oncol (R Coll Radiol) 2010 Nov;22(9):747-54. Epub 2010 Aug 25 doi: 10.1016/j.clon.2010.07.010. PMID: 20800458
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Clinical prediction guides

Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial.
De Laere B, Crippa A, Discacciati A, Larsson B, Persson M, Johansson S, D'hondt S, Bergström R, Chellappa V, Mayrhofer M, Banijamali M, Kotsalaynen A, Schelstraete C, Vanwelkenhuyzen JP, Hjälm-Eriksson M, Pettersson L, Ullén A, Lumen N, Enblad G, Thellenberg Karlsson C, Jänes E, Sandzén J, Schatteman P, Nyre Vigmostad M, Olsson M, Ghysel C, Sautois B, De Roock W, Van Bruwaene S, Anden M, Verbiene I, De Maeseneer D, Everaert E, Darras J, Aksnessether BY, Luyten D, Strijbos M, Mortezavi A, Oldenburg J, Ost P, Eklund M, Grönberg H, Lindberg J
Nat Med 2024 Nov;30(11):3291-3302. Epub 2024 Aug 20 doi: 10.1038/s41591-024-03204-2. PMID: 39164518Free PMC Article
A systematic review and meta-analysis on complications of transanal total mesorectal excision.
An Y, Roodbeen SX, Talboom K, Tanis PJ, Bemelman WA, Hompes R
Colorectal Dis 2021 Oct;23(10):2527-2538. Epub 2021 Jul 11 doi: 10.1111/codi.15792. PMID: 34174138
Postoperative patient comfort in suprapubic drainage versus transurethral catheterization following robot-assisted radical prostatectomy: a prospective randomized clinical trial.
Harke N, Godes M, Habibzada J, Urbanova K, Wagner C, Zecha H, Addali M, Witt JH
World J Urol 2017 Mar;35(3):389-394. Epub 2016 Jun 22 doi: 10.1007/s00345-016-1883-6. PMID: 27334135
Primary and secondary malignant involvement of gynaecological organs at radical cystectomy for bladder cancer: review of literature and retrospective analysis of 360 cases.
Salem H, El-Mazny A
J Obstet Gynaecol 2012 Aug;32(6):590-3. doi: 10.3109/01443615.2012.693980. PMID: 22779969
Bowen's disease involving the urethra.
Yasuda M, Tamura A, Shimizu A, Takahashi A, Ishikawa O
J Dermatol 2005 Mar;32(3):210-3. doi: 10.1111/j.1346-8138.2005.tb00747.x. PMID: 15863869

Recent systematic reviews

Functional outcomes and health-related quality of life following penile cancer surgery: a comprehensive review.
Croghan SM, Cullen IM, Raheem O
Sex Med Rev 2023 Sep 27;11(4):441-459. doi: 10.1093/sxmrev/qead021. PMID: 37204120
A systematic review and meta-analysis on complications of transanal total mesorectal excision.
An Y, Roodbeen SX, Talboom K, Tanis PJ, Bemelman WA, Hompes R
Colorectal Dis 2021 Oct;23(10):2527-2538. Epub 2021 Jul 11 doi: 10.1111/codi.15792. PMID: 34174138
Ureteral involvement by metastatic malignant disease.
Hu J, Deng J, Guo J, Fu B
Clin Exp Metastasis 2019 Dec;36(6):499-509. Epub 2019 Aug 24 doi: 10.1007/s10585-019-09989-8. PMID: 31446521
Pelvic Complications After Prostate Cancer Radiation Therapy and Their Management: An International Collaborative Narrative Review.
Matta R, Chapple CR, Fisch M, Heidenreich A, Herschorn S, Kodama RT, Koontz BF, Murphy DG, Nguyen PL, Nam RK
Eur Urol 2019 Mar;75(3):464-476. Epub 2018 Dec 17 doi: 10.1016/j.eururo.2018.12.003. PMID: 30573316
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article

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